ReferenceCitation: Norgren L, North R, Baumgartner I, Berger JS, Blomster JI, Hiatt WR, Jones WS, Katona BG, Mahaffey KW, Mulder H, Patel MR, Rockhold FW, Fowkes FGR. World regional differences in outcomes for patients with peripheral artery disease: Insights from the EUCLID trial. Vasc Med. 2021 Sep 13:1358863X211038620. doi: 10.1177/1358863X211038620. [Epub ahead of print]

name: Faculty of Medicine and Health, Örebro University, Örebro, Sweden

family: Norgren

full_name: Lars Norgren

given: Lars

name: Department of Statistics, North Carolina State University, Raleigh, NC, USA

family: North

full_name: Rebecca North

given: Rebecca

name: Division of Angiology, Swiss Cardiovascular Centre, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland

family: Baumgartner

full_name: Iris Baumgartner

given: Iris

name: Departments of Medicine and Department of Surgery, New York University School of Medicine, New York, NY, USA

family: Berger

full_name: Jeffrey S Berger

given: Jeffrey S

name: Turku University Hospital, University of Turku, Turku, Finland

family: Blomster

full_name: Juuso I Blomster

given: Juuso I

name: Division of Cardiology, Department of Medicine, University of Colorado School of Medicine, Aurora, CO, USA

family: Hiatt

full_name: William R Hiatt

given: William R

name: Duke Clinical Research Institute, Durham, NC, USA

name: Division of Cardiology, Department of Medicine, Duke University School of Medicine, Durham, NC, USA

family: Jones

full_name: W Schuyler Jones

given: W Schuyler

name: AstraZeneca Gaithersburg, Gaithersburg, MD, USA

family: Katona

full_name: Brian G Katona

given: Brian G

name: Stanford Center for Clinical Research, Stanford University School of Medicine, Stanford, CA, USA

family: Mahaffey

full_name: Kenneth W Mahaffey

given: Kenneth W

family: Mulder

full_name: Hillary Mulder

given: Hillary

family: Patel

full_name: Manesh R Patel

given: Manesh R

family: Rockhold

full_name: Frank W Rockhold

given: Frank W

name: Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK

family: Fowkes

full_name: F Gerry R Fowkes

given: F Gerry R

journal_name: Vascular Medicine

evidence: open (via page says license)

license: cc-by

license_normalized: cc-by

ReferenceCitation: Hiatt WR, Hess CN, Bonaca MP, Kavanagh S, Patel MR, Baumgartner I, Berger JS, Blomster JI, Jones WS, Katona BG, Mahaffey KW, Norgren L, Rockhold FW, Fowkes FGR. Ankle-Brachial Index for Risk Stratification in Patients With Symptomatic Peripheral Artery Disease With and Without Prior Lower Extremity Revascularization: Observations From the EUCLID Trial. Circ Cardiovasc Interv. 2021 Jul;14(7):e009871. doi: 10.1161/CIRCINTERVENTIONS.120.009871. Epub 2021 Jul 13.

name: Division of Cardiology, University of Colorado School of Medicine, Aurora (W.R.H., C.N.H., M.P.B.).

name: CPC Clinical Research, Aurora, CO (W.R.H., C.N.H., M.P.B., S.K.).

full_name: William R. Hiatt

given: William R.

family: Hess

full_name: Connie N. Hess

given: Connie N.

family: Bonaca

full_name: Marc P. Bonaca

given: Marc P.

family: Kavanagh

full_name: Sarah Kavanagh

given: Sarah

name: Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC (M.R.P., W.S.J., F.W.R.).

full_name: Manesh R. Patel

given: Manesh R.

name: Swiss Cardiovascular Center, University of Bern, Switzerland (I.B.).

name: Departments of Medicine and Surgery, New York University School of Medicine (J.S.B.).

full_name: Jeffrey S. Berger

given: Jeffrey S.

full_name: Juuso I. Blomster

given: Juuso I.

name: Stanford Center for Clinical Research, Stanford University School of Medicine, CA (K.W.M.).

name: Faculty of Medicine and Health, Örebro University, Sweden (L.N.).

name: Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, United Kingdom (F.G.R.F).

ReferenceCitation: Hsia J, Kavanagh ST, Hopley CW, Baumgartner I, Berger JS, Fowkes GR, Jones WS, Mahaffey KW, Norgren L, Patel MR, Rockhold F, Blomster J, Katona BG, Hiatt WR, Bonaca MP. Impact of chronic kidney disease on hemoglobin among patients with peripheral artery disease treated with P2Y(12) inhibitors: Insights from the EUCLID trial. Vasc Med. 2021 Jun 3:1358863X211017641. doi: 10.1177/1358863X211017641. [Epub ahead of print]

name: Department of Medicine, University of Colorado School of Medicine, Aurora, CO, USA

name: Department of Medicine, Geisel School of Medicine at Dartmouth, Dartmouth Hitchcock Medical Center, Hanover, NH, USA

name: Department of Angiology, Inselspital, Bern, Switzerland

name: Departments of Medicine and Surgery, New York University School of Medicine, New York, NY, USA

name: Centre for Population Health Sciences, University of Edinburgh, Edinburgh, Scotland

name: Duke Clinical Research Institute, Duke University, Durham, NC, USA

name: Stanford University School of Medicine, Palo Alto, CA, USA

name: Faculty of Medicine and Health, Örebro University Hospital, Örebro, Sweden

name: AstraZeneca LP, Gothenburg, Sweden; Gaithersburg, MD, USA

title: Impact of chronic kidney disease on hemoglobin among patients with peripheral artery disease treated with P2Y12 inhibitors: Insights from the EUCLID trial

ReferenceCitation: Galani J, Mulder H, Rockhold FW, Weissler EH, Baumgartner I, Berger JS, Blomster JI, Fowkes FGR, Hiatt WR, Katona BG, Norgren L, Mahaffey KW, Quint JK, Patel MR, Jones WS. Association of Chronic Obstructive Pulmonary Disease with Morbidity and Mortality in Patients with Peripheral Artery Disease: Insights from the EUCLID Trial. Int J Chron Obstruct Pulmon Dis. 2021 Mar 29;16:841-851. doi: 10.2147/COPD.S292978. eCollection 2021.

journal_name: International Journal of Chronic Obstructive Pulmonary Disease

repository_institution: University Library Bern - BORIS - Bern Open Repository and Information System

repositories_institution: University Library Bern - BORIS - Bern Open Repository and Information System

ReferenceCitation: Kochar A, Mulder H, Rockhold FW, Baumgartner I, Berger JS, Blomster JI, Fowkes FGR, Katona BG, Lopes RD, Al-Khalidi HR, Mahaffey KW, Norgren L, Hiatt WR, Patel MR, Jones WS. Cause of Death Among Patients With Peripheral Artery Disease: Insights From the EUCLID Trial. Circ Cardiovasc Qual Outcomes. 2020 Nov;13(11):e006550. doi: 10.1161/CIRCOUTCOMES.120.006550. Epub 2020 Nov 12.

name: Division of Cardiovascular Medicine, Brigham and Women’s Hospital, Boston, MA (A.K.).

name: Duke Clinical Research Institute (H.M., F.W.R., R.D.L., H.R.A.-K., M.R.P.), Duke University, Durham, NC.

name: Swiss Cardiovascular Centre, Inselspital, Bern University Hospital, University of Switzerland (I.B.).

name: Heart Centre, Turku University Hospital, Finland (J.I.B.).

name: Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, United Kingdom (F.G.R.F.).

name: Duke Heart Center, Division of Cardiology, School of Medicine (R.D.L., M.R.P., W.S.J.), Duke University, Durham, NC.

name: University of Colorado School of Medicine and CPC Clinical Research, Aurora (W.R.H.).

journal_name: Circulation: Cardiovascular Quality and Outcomes

title: Cause of Death Among Patients With Peripheral Artery Disease

ReferenceCitation: Gutierrez JA, Heizer GM, Jones WS, Rockhold FW, Mahaffey KW, Fowkes FGR, Berger JS, Baumgartner I, Held P, Katona BG, Norgren L, Blomster JI, Hiatt WR, Patel MR. CYP2C19 status and risk of major adverse cardiovascular events in peripheral artery disease: Insights from the EUCLID Trial. Am Heart J. 2020 Nov;229:118-120. doi: 10.1016/j.ahj.2020.07.017. Epub 2020 Aug 16.

ReferenceCitation: Fudim M, Hopley CW, Huang Z, Kavanagh S, Rockhold FW, Baumgartner I, Berger JS, Blomster JI, Fowkes FGR, Katona BG, Mahaffey KW, Norgren L, Ostrom C, Patel MR, Jones WS, Hiatt WR. Association of Hypertension and Arterial Blood Pressure on Limb and Cardiovascular Outcomes in Symptomatic Peripheral Artery Disease: The EUCLID Trial. Circ Cardiovasc Qual Outcomes. 2020 Sep;13(9):e006512. doi: 10.1161/CIRCOUTCOMES.120.006512. Epub 2020 Aug 31.

name: Duke Clinical Research Institute, Department of Medicine, Duke University School of Medicine, Durham, NC (M.F., Z.H., F.W.R., M.R.P., W.S.J.).

name: Department of Medicine, Section of Nephrology and Hypertension, Geisel School of Medicine at Dartmouth College, Hanover, NH (C.W.H.).

name: CPC Clinical Research, Aurora, CO (S.K., C.O.).

name: University of Edinburgh, Usher Institute of Population Health Sciences and Informatics, United Kingdom (F.G.R.F.).

name: Orebro University, Faculty of Medicine and Health, Sweden (L.N.).

name: Department of Medicine University of Colorado School of Medicine, Division of Cardiology, and CPC Clinical Research, Aurora (W.R.H.).

ReferenceCitation: Long CA, Mulder H, Fowkes FGR, Baumgartner I, Berger JS, Katona BG, Mahaffey KW, Norgren L, Blomster JI, Rockhold FW, Hiatt WR, Patel MR, Jones WS, Nehler MR. Incidence and Factors Associated With Major Amputation in Patients With Peripheral Artery Disease: Insights From the EUCLID Trial. Circ Cardiovasc Qual Outcomes. 2020 Jul;13(7):e006399. doi: 10.1161/CIRCOUTCOMES.119.006399. Epub 2020 Jul 3.

name: Department of Surgery, Division of Vascular Surgery and Endovascular Surgery (C.A.L.), Duke University Health System, Durham, NC.

name: Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC (H.M., F.W.R., M.R.P., W.S.J.).

name: Division of Angiology, Swiss Cardiovascular Centre, Inselspital, Bern University Hospital, University of Bern, Switzerland (I.B.).

name: Departments of Medicine (J.S.B.), New York University School of Medicine.

name: Surgery (J.S.B.), New York University School of Medicine.

name: Heart Centre, Turku University Hospital, University of Turku, Finland (J.I.B.).

name: Department of Medicine, Division of Cardiology (W.R.H.), University of Colorado School of Medicine and CPC Clinical Research, Aurora.

name: Department of Medicine, Division of Cardiology (M.R.P., W.S.J.), Duke University Health System, Durham, NC.

name: Department of Surgery, Division of Vascular Surgery and Endovascular Surgery (M.R.N.), University of Colorado School of Medicine and CPC Clinical Research, Aurora.

title: Incidence and Factors Associated With Major Amputation in Patients With Peripheral Artery Disease

ReferenceCitation: Haine A, Kavanagh S, Berger JS, Hess CN, Norgren L, Fowkes FGR, Katona BG, Mahaffey KW, Blomster JI, Patel MR, Jones WS, Rockhold FW, Hiatt WR, Baumgartner I; International Steering Committee and Investigators of the EUCLID Trial. Sex-Specific Risks of Major Cardiovascular and Limb Events in Patients With Symptomatic Peripheral Artery Disease. J Am Coll Cardiol. 2020 Feb 18;75(6):608-617. doi: 10.1016/j.jacc.2019.11.057.

repository_institution: University of Edinburgh - Edinburgh Research Explorer

repositories_institution: University of Edinburgh - Edinburgh Research Explorer

ReferenceCitation: Ward R, Huang Z, Rockhold FW, Baumgartner I, Berger JS, Blomster JI, Fowkes FGR, Katona BG, Mahaffey KW, Norgren L, Vemulapalli S, Povsic TJ, Mehta R, Hiatt WR, Patel MR, Jones WS. Major bleeding in patients with peripheral artery disease: Insights from the EUCLID trial. Am Heart J. 2020 Feb;220:51-58. doi: 10.1016/j.ahj.2019.11.007. Epub 2019 Nov 18.

title: Major bleeding in patients with peripheral artery disease: Insights from the EUCLID trial

ReferenceCitation: Hopley CW, Kavanagh S, Patel MR, Ostrom C, Baumgartner I, Berger JS, Blomster JI, Fowkes FGR, Jones WS, Katona BG, Mahaffey KW, Norgren L, Rockhold FW, Hiatt WR. Chronic kidney disease and risk for cardiovascular and limb outcomes in patients with symptomatic peripheral artery disease: The EUCLID trial. Vasc Med. 2019 Oct;24(5):422-430. doi: 10.1177/1358863X19864172. Epub 2019 Jul 24.

name: Department of Medicine, Section of Nephrology and Hypertension, Geisel School of Medicine at Dartmouth, Dartmouth Hitchcock Medical Center, Hanover, NH, USA

name: Department of Medicine, Division of Cardiology, Duke University School of Medicine, Durham, NC, USA

name: Swiss Cardiovascular Centre, Inselspital, Division of Angiology, Bern University Hospital, University of Bern, Bern, Switzerland

name: Department of Medicine, Division of Cardiology, University of Colorado School of Medicine, Aurora, CO, USA

ReferenceCitation: Hess CN, Huang Z, Patel MR, Baumgartner I, Berger JS, Blomster JI, Fowkes FGR, Held P, Jones WS, Katona B, Mahaffey KW, Norgren L, Rockhold FW, Hiatt WR. Acute Limb Ischemia in Peripheral Artery Disease. Circulation. 2019 Aug 13;140(7):556-565. doi: 10.1161/CIRCULATIONAHA.119.039773. Epub 2019 Jun 26.

name: Division of Cardiology, Department of Medicine, University of Colorado School of Medicine and CPC Clinical Research, Aurora (C.N.H., W.R.H.).

name: Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC (Z.H., M.R.P., W.S.J., F.W.R.).

name: Swiss Cardiovascular Center, Inselspital–Bern University Hospital, University of Bern, Switzerland (I.B.).

name: Turku University Hospital, Finland (J.I.B.).

name: University of Gothenburg, Sweden (P.H.).

title: Acute Limb Ischemia in Peripheral Artery Disease

ReferenceCitation: Kolls BJ, Sapp S, Rockhold FW, Jordan JD, Dombrowski KE, Fowkes FGR, Mahaffey KW, Berger JS, Katona BG, Blomster JI, Norgren L, Abramson BL, Leiva-Pons JL, Prieto JC, Sokurenko G, Hiatt WR, Jones WS, Patel MR. Stroke in Patients With Peripheral Artery Disease. Stroke. 2019 Jun;50(6):1356-1363. doi: 10.1161/STROKEAHA.118.023534. Epub 2019 May 16.

name: From the Department of Neurology (B.J.K., K.E.D.), Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC

name: Department of Statistics (S.S., F.W.R.), Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC

name: Department of Neurology, University of North Carolina School of Medicine, Chapel Hill (J.D.J.)

name: Stanford Center for Clinical Research, Stanford University School of Medicine, CA (K.W.M.)

name: Department of Medicine and Surgery, New York University School of Medicine (J.S.B.)

name: Turku University Hospital, Department of Medicine, University of Turku, Finland (J.I.B.)

name: Faculty of Medicine and Health, Örebro University, Sweden (L.N.)

name: Division of Cardiology, St. Michael’s Hospital, Department of Medicine, University of Toronto, ON, Canada (B.L.A.)

name: Department of Cardiology, Hospital Central Dr. Ignacio Morones Prieto, San Luis Potosi, Mexico (J.L.L.-P.)

name: Cardiovascular Department, Clinical Hospital, and Pharmacology Program ICBM, Faculty of Medicine, University of Chile, Santiago (J.C.P.)

name: The Nikiforov Russian Center of Emergency and Radiation Medicine, Consulting Diagnostic Center No. 85, St. Petersburg, Russia (G.S.)

name: University of Colorado School of Medicine, Division of Cardiology and CPC Clinical Research, Aurora (W.R.H.).

name: Division of Cardiology, Department of Medicine (W.S.J., M.R.P.), Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC

title: Stroke in Patients With Peripheral Artery Disease

ReferenceCitation: Low Wang CC, Blomster JI, Heizer G, Berger JS, Baumgartner I, Fowkes FGR, Held P, Katona BG, Norgren L, Jones WS, Lopes RD, Olin JW, Rockhold FW, Mahaffey KW, Patel MR, Hiatt WR; EUCLID Trial Executive Committee and Investigators. Cardiovascular and Limb Outcomes in Patients With Diabetes and Peripheral Artery Disease: The EUCLID Trial. J Am Coll Cardiol. 2018 Dec 25;72(25):3274-3284. doi: 10.1016/j.jacc.2018.09.078. Erratum in: J Am Coll Cardiol. 2019 Jul 16;74(2):264-269.

title: Cardiovascular and Limb Outcomes in Patients With Diabetes and Peripheral Artery Disease

ReferenceCitation: Olivier CB, Mulder H, Hiatt WR, Jones WS, Fowkes FGR, Rockhold FW, Berger JS, Baumgartner I, Held P, Katona BG, Norgren L, Blomster J, Patel MR, Mahaffey KW. Incidence, Characteristics, and Outcomes of Myocardial Infarction in Patients With Peripheral Artery Disease: Insights From the EUCLID Trial. JAMA Cardiol. 2019 Jan 1;4(1):7-15. doi: 10.1001/jamacardio.2018.4171.

name: Stanford Center for Clinical Research, Department of Medicine, Stanford University School of Medicine, Stanford, California

name: Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina

name: Division of Cardiology, University of Colorado School of Medicine, Aurora

name: CPC Clinical Research, University of Colorado School of Medicine, Aurora

name: Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, United Kingdom

name: Department of Medicine, New York University School of Medicine, New York

name: Department of Surgery, New York University School of Medicine, New York

name: Swiss Cardiovascular Center, Inselspital, University of Bern, Bern, Switzerland

name: AstraZeneca Gaithersburg, Gaithersburg, Maryland

name: Turku University Hospital, Turku, Finland

title: Incidence, Characteristics, and Outcomes of Myocardial Infarction in Patients With Peripheral Artery Disease

ReferenceCitation: Baumgartner I, Norgren L, Fowkes FGR, Mulder H, Patel MR, Berger JS, Jones WS, Rockhold FW, Katona BG, Mahaffey K, Hiatt WR; Executive Committee and Investigators of the EUCLID Trial. Cardiovascular Outcomes After Lower Extremity Endovascular or Surgical Revascularization: The EUCLID Trial. J Am Coll Cardiol. 2018 Oct 2;72(14):1563-1572. doi: 10.1016/j.jacc.2018.07.046.

title: Cardiovascular Outcomes After Lower Extremity Endovascular or Surgical Revascularization

ReferenceCitation: Berger JS, Abramson BL, Lopes RD, Heizer G, Rockhold FW, Baumgartner I, Fowkes FGR, Held P, Katona BG, Norgren L, Jones WS, Millegård M, Blomster J, Reist C, Hiatt WR, Patel MR, Mahaffey KW. Ticagrelor versus clopidogrel in patients with symptomatic peripheral artery disease and prior coronary artery disease: Insights from the EUCLID trial. Vasc Med. 2018 Dec;23(6):523-530. doi: 10.1177/1358863X18775594. Epub 2018 Jul 11.

name: University of Toronto, Toronto, ON, Canada

name: Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA

name: Swiss Cardiovascular Center, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland

name: University of Colorado School of Medicine and CPC Clinical Research, Aurora, CO, USA

ReferenceCitation: Norgren L, Patel MR, Hiatt WR, Wojdyla DM, Fowkes FGR, Baumgartner I, Mahaffey KW, Berger JS, Jones WS, Katona BG, Held P, Blomster JI, Rockhold FW, Björck M; EUCLID Steering Committee and Investigators. Outcomes of Patients with Critical Limb Ischaemia in the EUCLID Trial. Eur J Vasc Endovasc Surg. 2018 Jan;55(1):109-117. doi: 10.1016/j.ejvs.2017.11.006. Epub 2017 Dec 20.

journal_name: European Journal of Vascular and Endovascular Surgery

title: Outcomes of Patients with Critical Limb Ischaemia in the EUCLID Trial

ReferenceCitation: Hiatt WR, Fowkes FG, Heizer G, Berger JS, Baumgartner I, Held P, Katona BG, Mahaffey KW, Norgren L, Jones WS, Blomster J, Millegård M, Reist C, Patel MR; EUCLID Trial Steering Committee and Investigators. Ticagrelor versus Clopidogrel in Symptomatic Peripheral Artery Disease. N Engl J Med. 2017 Jan 5;376(1):32-40. doi: 10.1056/NEJMoa1611688. Epub 2016 Nov 13.

repository_institution: University of Dundee - Discovery Research Portal

repositories_institution: University of Dundee - Discovery Research Portal

title: Ticagrelor versus Clopidogrel in Symptomatic Peripheral Artery Disease

ReferenceCitation: Jones WS, Baumgartner I, Hiatt WR, Heizer G, Conte MS, White CJ, Berger JS, Held P, Katona BG, Mahaffey KW, Norgren L, Blomster J, Millegård M, Reist C, Patel MR, Fowkes FG; International Steering Committee and Investigators of the EUCLID Trial. Ticagrelor Compared With Clopidogrel in Patients With Prior Lower Extremity Revascularization for Peripheral Artery Disease. Circulation. 2017 Jan 17;135(3):241-250. doi: 10.1161/CIRCULATIONAHA.116.025880. Epub 2016 Nov 13.

name: From Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC (W.S.J., G.H., C.R., M.P.P.); Swiss Cardiovascular Centre, Inselspital, Bern University Hospital, University of Bern, Switzerland (I.B.); University of Colorado School of Medicine and CPC Clinical Research, Aurora (W.R.H.); Department of Surgery, University of California San Francisco (M.S.C.); Department of Cardiology, Ochsner Clinical School, University of Queensland, Australia (C.J.W.); Ochsner Medical Center,...

ReferenceCitation: Held P, Himmelmann A, Ditmarsch M. Ticagrelor for the treatment of atherosclerotic disease: insights from the PARTHENON clinical development program. Future Cardiol. 2016 Jul;12(4):405-18. doi: 10.2217/fca-2016-0028. Epub 2016 May 10. Review.

name: Global Medicines Development, AstraZeneca Gothenburg, Pepparedsleden 1, SE-431 83 Mölndal, Sweden

location_country:
Romania
Russian Federation
Ukraine
France
Japan
Poland
Slovakia
Thailand
Argentina
Canada
Korea, Republic of
Chile
Sweden
Netherlands
Philippines
Vietnam
Bulgaria
Hungary
China
United States
Germany
United Kingdom
Italy
Brazil
Mexico
Czechia
Spain
Turkey

title: A Randomized, Double-blind, Parallel Group, Multicentre Phase IIIb Study to Compare Ticagrelor With Clopidogrel Treatment on the Risk of Cardiovascular Death, Myocardial Infarction and Ischemic Stroke in Patients With Established Peripheral Artery Disease (EUCLID Examining Use of tiCagreLor In paD)

summary: The purpose of this study is to compare the effects of ticagrelor and clopidogrel in patients with Peripheral Artery Disease.


title: A Randomized, Multicenter, Multicountry Study to Evaluate the Effectiveness of Florbetapir (18F) PET Imaging in Changing Patient Management and to Evaluate the Relationship Between Florbetapir (18F) PET Scan Status and Cognitive Decline

summary: This study is designed to determine the effectiveness of florbetapir (18F) in changing patient management and to evaluate the association between scan status and cognitive decline.

status: Completed

study_completion_date_type: Actual

study_type: Interventional

design_allocation: Randomized

primary_purpose: Diagnostic

enrollment_type: Actual

lead_sponsor: Avid Radiopharmaceuticals

location_country:
Italy
United States
France

intervention_type: Drug

lead_sponsor_type: industriel

status_simplified: Completed


type: EudraCT Number

title: A Two-Cohort, Open-Label, Multicenter Study of Trastuzumab Emtansine (T-DM1) in HER2-Positive Locally Advanced or Metastatic Breast Cancer Patients Who Have Received Prior Anti-HER2 and Chemotherapy-Based Treatment

summary: This two-cohort, open-label, multicenter study will assess the safety, efficacy and tolerability of trastuzumab emtansine in participants with HER2-positive locally advanced breast cancer (LABC) or metastatic breast cancer (mBC) who have received prior anti-HER2 and chemotherapy-based treatment. Participants in Cohort 1 will be drawn from the general participant population; Cohort 2 will include only Asian participants.

study_start_date_type: Actual

design_allocation: Non-Randomized

primary_purpose: Treatment

ReferenceType: derived

ReferenceCitation: Engebraaten O, Yau C, Berg K, Borgen E, Garred Ø, Berstad MEB, Fremstedal ASV, DeMichele A, Veer LV', Esserman L, Weyergang A. RAB5A expression is a predictive biomarker for trastuzumab emtansine in breast cancer. Nat Commun. 2021 Nov 5;12(1):6427. doi: 10.1038/s41467-021-26018-z.

family: Engebraaten

full_name: Olav Engebraaten

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sequence: first

family: Yau

full_name: Christina Yau

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sequence: additional

family: Berg

full_name: Kristian Berg

given: Kristian

family: Borgen

full_name: Elin Borgen

given: Elin

family: Garred

full_name: Øystein Garred

given: Øystein

family: Berstad

full_name: Maria E. B. Berstad

given: Maria E. B.

family: Fremstedal

full_name: Ane S. V. Fremstedal

given: Ane S. V.

family: DeMichele

full_name: Angela DeMichele

given: Angela

family: Veer

full_name: Laura van ’t Veer

given: Laura van ’t

family: Esserman

full_name: Laura Esserman

given: Laura

family: Weyergang

full_name: Anette Weyergang

given: Anette

bso_classification: Medical research

currency_apc_doaj: GBP

datasource: user

genre: journal-article

genre_raw: journal-article

journal_name: Nature Communications

oa_colors: green gold

oa_host_type: publisher;repository

evidence: oa journal (via doaj)

host_type: publisher

version: publishedVersion

evidence: oa repository (via OAI-PMH title and last author match)

host_type: repository

license_normalized: no license

repository_institution: Cold Spring Harbor Laboratory - medRxiv

repository_normalized: medRxiv

version: submittedVersion

publisher: Springer Science and Business Media LLC

publisher_dissemination: Springer-Nature

publisher_group: Springer-Nature

publisher_normalized: Springer

ReferenceCitation: Montemurro F, Delaloge S, Barrios CH, Wuerstlein R, Anton A, Brain E, Hatschek T, Kelly CM, Peña-Murillo C, Yilmaz M, Donica M, Ellis P. Trastuzumab emtansine (T-DM1) in patients with HER2-positive metastatic breast cancer and brain metastases: exploratory final analysis of cohort 1 from KAMILLA, a single-arm phase IIIb clinical trial(☆). Ann Oncol. 2020 Oct;31(10):1350-1358. doi: 10.1016/j.annonc.2020.06.020. Epub 2020 Jul 5.

family: Montemurro

full_name: F. Montemurro

given: F.

family: Delaloge

full_name: S. Delaloge

given: S.

family: Barrios

full_name: C.H. Barrios

family: Wuerstlein

full_name: R. Wuerstlein

given: R.

family: Anton

full_name: A. Anton

given: A.

family: Brain

full_name: E. Brain

given: E.

family: Hatschek

evidence: oa repository (via OAI-PMH title and first author match)

title: Trastuzumab emtansine (T-DM1) in patients with HER2-positive metastatic breast cancer and brain metastases: exploratory final analysis of cohort 1 from KAMILLA, a single-arm phase IIIb clinical trial☆

location_country:
Luxembourg
Peru
Guatemala
Finland
Greece
Australia
Belgium
Denmark
Taiwan
Iceland
Ecuador
Croatia
France
Panama
Poland
Slovakia
Norway
Thailand
Argentina
Indonesia
Canada
Slovenia
Korea, Republic of
Turkey
Sweden
United Arab Emirates
Hong Kong
Netherlands
Bulgaria
Hungary
Ireland
China
Portugal
Germany
United Kingdom
Italy
Austria
Brazil
Mexico
Dominican Republic
Venezuela
Spain
Estonia

location_facility: Polyclinique Bordeaux Nord Aquitaine; Chimiotherapie Radiotherapie

location_facility: A.O.U.I. VERONA-OSPEDALE BORGO TRENTO; ONCOLODIA MEDICA-d.O.

location_facility: Polyclinique De Courlancy; Centre Radiotherapie Oncologie

location_facility: Department of Surgery, King Chulalongkorn Memorial Hospital

location_facility: Odense Universitetshospital, Onkologisk Afdeling R

location_facility: Lkh Salzburg - Univ. Klinikum Salzburg; Iii. Medizinische Abt.

location_facility: Aalborg Universitetshospital, Klinik Kirurgi-Kræft, Onkologisk afd.

location_facility: Institut für Versorgungsforschung in der Onkologie GbR Koblenz

location_facility: A.O. Città della Salute e della Scienza - Presidio Molinette; divisione oncologia medica

location_facility: Hospital Universitario Materno Infantil de Gran Canaria; Servicio de Oncologia

location_facility: Hopital Morvan; Oncologie - Radiotherapie

location_facility: Centro Oncológico Sixtino / Centro Oncológico SA

location_facility: Hospital de Donostia; Servicio de Oncologia Medica

location_facility: University Hospital Birmingham Queen Elizabeth Hospital

location_facility: Narodny Onkologicky Ustav; Oddelenie klinickej onkologie A

location_facility: Corporacio Sanitaria Parc Tauli; Servicio de Oncologia

location_facility: Hämatologisch-onkologische Praxis Dr. med. - Heinrich, - Bangerter

location_facility: Ospedale S.S. Trinità Nuovo; Divisione Oncologia

location_facility: Chu Grenoble - Hopital Albert Michallon; Departement de Cancero-Hematologie

location_facility: Turku Uni Central Hospital; Oncology Clinics

location_facility: Az. Osp. Ospedale Civile; U.O. Di Oncologia Medica Ed Ematologia

location_facility: Yonsei University Severance Hospital; Medical Oncology

location_facility: Hospital Quiron de Madrid; Servicio de Oncologia

location_facility: Hospital Quiron Barcelona; Servicio de Oncologia

location_facility: Orszagos Onkologiai Intezet; B Belgyogyaszati Osztaly

location_facility: Royal Devon & Exeter Hospital; Oncology Centre

location_facility: Hospital Universitari Germans Trias i Pujol; Servicio de Oncologia

location_facility: University Hospital of Patras Medical Oncology

location_facility: Korea University Anam Hospital; Oncology Haemotology

location_facility: Hospital Severo Ochoa; Servicio de Oncologia

location_facility: Centro Oncologico Riojano Integral (CORI)

location_facility: Hospital General de Elda; Servicio de Oncologia

location_facility: Centre Alexis Vautrin; Oncologie Medicale

location_facility: Inst. Nacional de Cancerologia; Investigacion Clinica

location_facility: Cli De La Porte De Saint Cloud; Hop De Jour De Chimiotherapie

location_facility: Hospital San Pedro De Alcantara; Servicio de Oncologia

location_facility: Complejo Hospitalario de Pontevedra; Servicio de Oncologia

location_facility: Medizinische Hochschule Zentrum Frauenheilkunde Abt.Gynäkologische Onkologie

location_facility: Hospital de Gran Canaria Dr. Negrin; Servicio de Oncologia

location_facility: Kartal Dr Lutfi Kirdar Sehir Hastanesi; Medical Oncology Department

location_facility: RCCS - Centro di Riferimento; Oncologia Medica B

location_facility: Clinique Tivoli; Chimiotherapie Radiotherapie

location_facility: Instituto Valenciano Oncologia; Oncologia Medica

location_facility: Gaziantep University Medical Faculty, Medical Oncology Department

location_facility: Castle Hill Hospital; The Queen's Centre for Oncology & Haematology

location_facility: Plymouth Oncology Centre; Clinical Trials Unit

location_facility: Cipto Mangunkusumo General Hospital; Hematology & Oncology

location_facility: Szpital Uniwersytecki w Krakowie, Oddział Kliniczny Kliniki Onkologii

location_facility: Southlake Regional Health Center; Community Care Clinic / Oncology

location_facility: Peter MacCallum Cancer Centre; Medical Oncology

location_facility: Calvary Mater Newcastle; Medical Oncology

location_facility: Kaposi Mor County Hospital; Dept. of Oncology

location_facility: Fakultna nemocnica Trencín; Onkologicke odd.

location_facility: Oslo Universitetssykehus HF; Ullevål sykehus

location_facility: St Vincent'S Uni Hospital; Medical Oncology

location_facility: Hospital Universitari Sant Joan de Reus; Servicio de Oncologia

location_facility: Hospital Universitari Arnau de Vilanova de Lleida; Servicio de Oncologia

location_facility: Chi-Mei Medical Centre; Hematology & Oncology

location_facility: VETERANS GENERAL HOSPITAL; Department of General Surgery

location_facility: Hospital Clinico Universitario de Valencia; Servicio de Onco-hematologia

location_facility: Centre Rene Huguenin; CONSULT SPECIALISEES

location_facility: Az Ospedaliera Nuovo Garibaldi Quartiere Nesima; Oncologia Medica

location_facility: Hämatologisch-Onkologische Schwerpunktpraxis; Dres. Schlag & Schöttker

location_facility: Institut Paoli Calmettes; Oncologie Medicale

location_facility: Prince of Wales Hosp; Dept. Of Clinical Onc

location_facility: Universitaetsfrauenklinik; Und Poliklinik Am Klinikum

location_facility: MHAT Serdika; Department of medical oncology

location_facility: Clinique Armoricaine Radiologie; Hopital de Jour

location_facility: Yeovil District Hospital; Macmillan Cancer Unit

location_facility: Irccs Istituto Nazionale Dei Tumori (Int);S.C. Medicina Oncologica 1

location_facility: Institut Claudius Regaud; Departement Oncologie Medicale

location_facility: National Cheng Kung Uni Hospital; Surgery

location_facility: Hospital de Jerez de la Frontera; Servicio de Oncologia

location_facility: Centre Georges Francois Leclerc; Oncologie 3

location_facility: Klinikum Leverkusen; Med. Klinik III / Onkologie

location_facility: Europejskie Centrum Zdrowia Otwock Szpital im. Fryderyka Chopina, Klinika Onkologii

location_facility: Hospital Xeral Cíes; Servicio de Oncologia

location_facility: Haematology & Oncology Clinics of Australia Research Centre

location_facility: Christie Hospital; Breast Cancer Research Office

location_facility: IPO de Lisboa; Servico de Oncologia Medica

location_facility: Kyungpook National University Medical Center

location_facility: Unidad de Mastologia y Atencion a la Mujer

location_facility: IRCCS Istituto Nazionale Per La Ricerca Sul Cancro (IST); Oncologia Medica A

location_facility: Ospedale Misericordia E Dolce; Oncologia Medica

location_facility: Royal Victoria Regional Health Centre; c/o Oncology Clinical Trials

location_facility: Nordsjællands Hospital, Hillerød, Onkologisk Afdeling

location_facility: British Columbia Cancer Agency (Bcca) - Vancouver Cancer Centre

location_facility: Fondazione Del Piemonte Per L'oncologia Ircc Di Candiolo; Dipartimento Oncologico

location_facility: Azienda usl 5 Di Pisa-Ospedale Di Pontedera;U.O. Oncologia

location_facility: Herlev Hospital; Afdeling for Kræftbehandling

location_facility: Guys & St Thomas Hospital; Department of Oncology

location_facility: North Estonia Medical Centre Foundation; Oncology Center

location_facility: Hospital General Universitario de Elche; Servicio de Oncologia

location_facility: Hospital General Universitario de Valencia; Servicio de oncologia

location_facility: HELIOS Dr. Horst Schmidt Kliniken Wiesbaden; Klinik für Gynäkologie und gynäkologische Onkologie

location_facility: Mcgill University - Royal Victoria Hospital; Oncology

location_facility: Gazi Uni Medical Faculty Hospital; Oncology Dept

location_facility: Ch Bretagne Sud Site Scorff; Oncologie Medicale

location_facility: Azienda Ospedaliera San Giuseppe Moscati

location_facility: Azienda Ospedaliera Di Perugia Ospedale s. Maria Della Misericordia; Oncologia Medica

location_facility: Ege Uni Medical Faculty Hospital; Oncology Dept

location_facility: Hospital de Cruces; Servicio de Oncologia

location_facility: Western General Hospital; Clinical Oncology

location_facility: Deventer Ziekenhuis; Interne Geneeskunde

location_facility: Sana Klinikum Offenbach GmbH; Klinik für Gynäkologie & Geburtshilfe

location_facility: IPO do Porto; Servico de Oncologia Medica

location_facility: Hospital Univ. Central de Asturias; Servicio de Oncologia

location_facility: Orbis Medisch Centrum; Inwendige Geneeskunde

location_facility: HOSPITAL DE MADRID NORTE SANCHINARRO- CENTRO INTEGRAL ONCOLOGICO CLARA CAMPAL; Servicio de Oncologia

location_facility: Dr. H. Bliss Murphy Cancer Centre; Oncology

location_facility: Westmead Hospital; Medical Oncology and Pallative Care

location_facility: Hospital Ramon y Cajal; Servicio de Oncologia

location_facility: Cancer Hospital Chinese Academy of Medical Sciences.

location_facility: Hospital Privado De Comunidad; General Practice

location_facility: Tampere University Hospital; Dept of Oncology

location_facility: Bialostockie Centrum Onkologii; Oddzial Onkologii Klinicznej

location_facility: District Oncology Dispensary Wit Stationary

location_facility: Hospital da Luz; Departamento de Oncologia Medica

location_facility: Karolinska Hospital; Oncology - Radiumhemmet

location_facility: Hospital Universitario Reina Sofia; Servicio de Oncologia

location_facility: Świętokrzyskie Centrum Onkologii; Dział Chemioterapii

location_facility: Mater Misericordiae Uni Hospital; Oncology

location_facility: Hospital Universitari de Girona Dr. Josep Trueta; Servicio de Oncologia

location_facility: Institut Gustave Roussy; Pathologie Mammaire

location_facility: Medizinische Universität Wien; Univ.Klinik für Innere Medizin I - Abt. für Onkologie

location_facility: Dres. Joerg Weniger, Annette Bittrich und Berit Schuetze

location_facility: Klinikum der Universität München; Campus Großhadern; Klinik und Poliklinik für Frauenheilkunde

location_facility: Polyclinique Francheville; Med Chimiotherapie Radiotherapie

location_facility: St George'S Hospital; Oncology Research Office /Oncology Opd

location_facility: Maidstone & Tonbridge Wells Hospital; Kent Oncology Center

location_facility: Gachon Medical School Gil Medical Center; Medical Oncology

location_facility: Maharaj Nakorn Chiang Mai Hospital; Department of Surgery/Head Neck and Breast Unit; Clinical Trial

location_facility: Schwerpunktpraxis Onkologie/Hämatologie Dr. Dirk Pott, Dr. Christian Tirier und Carla Verena u.w.

location_facility: Uni Hospital of Ioannina; Oncology Dept.

location_facility: Casa di Cura Multimedica S.p.A.; Dipartimento Oncologico

location_facility: Centre Henri Becquerel; Oncologie Medicale

location_facility: Institut Jean Godinot; Oncologie Medicale

location_facility: Università degli Studi Federico II; Clinica di Oncologia Medica

location_facility: Ospedale Vito Fazzi; Div. Oncoematologia

location_facility: Antoni Van Leeuwenhoek Ziekenhuis; Inwendige Geneeskunde

location_facility: Harbin Medical University Cancer Hospital

location_facility: Marmara Uni Faculty of Medicine; Medical Oncology

location_facility: Bezmialem Vakif Univ Medical; Bezmialem Vakif Univ T

location_facility: Centre Antoine Lacassagne; Hopital De Jour A2

location_facility: Royal Lancaster Infirmary, Morecambe Bay Hospitals Nhs Trust

location_facility: Clinique De L Europe; Radiotherapie Chimiotherapie

location_facility: Twee Steden Ziekenhuis - Locatie Tilburg; Interne Geneesekunde

location_facility: Hospital Sirio Libanes; Centro de Oncologia

location_facility: KYS Sadesairaala; Syopatautien poliklinikka

location_facility: Ospedale Maggiore Della Carita; Oncologia Medica

location_facility: Mater Hospital; Patricia Ritchie Centre for Cancer Care and Research

location_facility: Magyar Honvedseg Egeszsegugyi Kozpont; Fázis I-es Klinikai Farmakológiai Vizsgálóhely

location_facility: Hospital General Univ. de Alicante; Servicio de Oncologia

location_facility: Istanbul Uni Cerrahpasa Medical Faculty Hospital; Medical Oncology

location_facility: CENTRO MÉDICO NACIONAL SIGLO XXI; Hospital de Especialidades Oncología

location_facility: Instituto de Oncologia y Hematologia UCV

location_facility: Sygehus Syd Roskilde; Onkologisk/haematologisk ambulatorium

location_facility: Ospedale Bellaria; U.O. Oncologia Medica

location_facility: Fondazione Salvatore Maugeri; Divisione Di Oncologia Medica

location_facility: Seoul National Uni Hospital; Dept. of Internal Medicine/Hematology/Oncology

location_facility: Kocaeli University Faculty of Medicine; Medical oncology

location_facility: Policlinico Umberto i di Roma; dip. Scienze Radiologiche, Oncologiche, Anatomopatologiche

location_facility: Papageorgiou General Hospital; Medical Oncology

location_facility: Szpital Specjalistyczny POO im. ks. B.Markiewicza; Dzienny Oddz Chemioter i Hematologii Onkol

location_facility: Hospital Universitario Miguel Servet; Servicio Oncologia

location_facility: Complejo Hospitalario Universitario A Coruña (CHUAC, Materno Infantil), Oncología

location_facility: University Hospital coventry; Oncology Department

location_facility: Spaarne Ziekenhuis; Inwendige Geneeskunde

location_facility: Landspitali University Hospital, Department of Medical Oncology

location_facility: Complejo Hospitalario de Jaen-Hospital Universitario Medico Quirurgico; Servicio de Oncologia

location_facility: Hospital Clinico Universitario Virgen de la Victoria; Servicio de Oncologia

location_facility: Istanbul Uni of Medicine Faculty; Oncology Dept

location_facility: University General Hospital of Heraklion

location_facility: Medizinische Universität Wien; Univ.Klinik für Frauenheilkunde - Klinik für Gynäkologie

location_facility: Ospedale Antonio Perrino; Oncologia Medica

location_facility: Instituto Nacional de Ciencias Médicas Y de La Nutricion Zubirán

location_facility: Istituto Nazionale Tumori Fondazione G. Pascale

location_facility: ASST DI CREMONA; Unità di Patologia Mammaria Senologia e Breast Unit

location_facility: Hospital Universitario San Cecilio; Servicio de Oncologia

location_facility: Pramongkutklao Hospital; Medicine - Medical Oncology Unit

location_facility: Universitätsklinikum Münster; Klinik für Frauenheilkunde und Geburtshilfe

location_facility: Centre Henry S Kaplan - CHU Bretonneau ; service oncologie

location_facility: Weston Park Hospital; Cancer Clinical Trials Centre

location_facility: Centre Val Aurelle Paul Lamarque; Recherche Clinique


title: European Survey of Sedation and Analgesia Practices for Newborns Admitted to Intensive Care Units

acronym: EUROPAINsurvey

summary:
EUROPAIN Survey is an epidemiological study aimed at assessing current clinical practices regarding the use of sedative and analgesic drugs in newborns admitted to NICUs or PICUs in different countries in Europe. This study is conducted as part of the NeoOpiod study.

The main objective of this study is to determine the current clinical practices regarding the use of sedative and analgesic drugs in newborns in intensive units in different countries in Europe. The principal criteria are: the frequency of ventilated neonates receiving sedation and analgesia, the medications used for sedation and analgesia in ventilated neonates, the length of use of medications administered for sedation and analgesia in ventilated neonates and similarities and differences in sedation and analgesia practices among European countries.

The secondary objectives are: a) to determine the proportion of neonatal units that have developed and implemented local written guidelines to provide continuous sedation and analgesia in ventilated newborn infants as well as to prevent and treat procedural pain, b) to document the published guidelines for neonatal analgesia and sedation in different European countries and develop consensus for common European standards that can be applied in all medical settings, c) to determine the frequency of use of pain assessment tools in ventilated newborn infants and evaluate their impact on pain management practices and d) to determine practices to assess and prevent withdrawal syndromes.

The EUROPAIN STUDY is observational and therefore it will not interfere with routine practices of participating units. No changes in diagnostic, therapeutic or any managing strategy of patients are imposed by the participation in this study. This epidemiological study will only collect data on clinical practices in each unit. It will include all neonates up to a corrected age of 44 weeks post conception.

The maximum duration of data collection for every included infant is 28 days. Data collection will stop before 28 days if the infant leaves the unit (discharge, death, transfer to another hospital). Data will be entered on a secure web-based questionnaire.

study_type: Observational

time_perspective: Prospective

ReferenceCitation: Lago P, Frigo AC, Baraldi E, Pozzato R, Courtois E, Rambaud J, Anand KJ, Carbajal R. Sedation and analgesia practices at Italian neonatal intensive care units: results from the EUROPAIN study. Ital J Pediatr. 2017 Mar 7;43(1):26. doi: 10.1186/s13052-017-0343-2.

family: Lago

full_name: Paola Lago

given: Paola

family: Frigo

full_name: Anna Chiara Frigo

given: Anna Chiara

family: Baraldi

full_name: Eugenio Baraldi

given: Eugenio

family: Pozzato

full_name: Roberta Pozzato

given: Roberta

family: Courtois

full_name: Emilie Courtois

given: Emilie

family: Rambaud

full_name: Jérôme Rambaud

given: Jérôme

family: Anand

full_name: Kanwaljeet J. S. Anand

given: Kanwaljeet J. S.

family: Carbajal

full_name: Ricardo Carbajal

given: Ricardo

journal_name: Italian Journal of Pediatrics

evidence: oa repository (via OAI-PMH doi match)

repository_institution: PubMed Central - Europe PMC

repository_normalized: PubMed Central

evidence: oa repository (via pmcid lookup)

ReferenceCitation: Carbajal R, Eriksson M, Courtois E, Boyle E, Avila-Alvarez A, Andersen RD, Sarafidis K, Polkki T, Matos C, Lago P, Papadouri T, Montalto SA, Ilmoja ML, Simons S, Tameliene R, van Overmeire B, Berger A, Dobrzanska A, Schroth M, Bergqvist L, Lagercrantz H, Anand KJ; EUROPAIN Survey Working Group. Sedation and analgesia practices in neonatal intensive care units (EUROPAIN): results from a prospective cohort study. Lancet Respir Med. 2015 Oct;3(10):796-812. doi: 10.1016/S2213-2600(15)00331-8. Epub 2015 Sep 24. Erratum in: Lancet Respir Med. 2015 Dec;3(12):e44.

family: Eriksson

full_name: Mats Eriksson

given: Mats

family: Boyle

full_name: Elaine Boyle

given: Elaine

family: Avila-Alvarez

full_name: Alejandro Avila-Alvarez

given: Alejandro

family: Andersen

full_name: Randi Dovland Andersen

given: Randi Dovland

family: Sarafidis

full_name: Kosmas Sarafidis

given: Kosmas

family: Polkki

full_name: Tarja Polkki

given: Tarja

repository_institution: RCAAP Project by FCT - Portuguese National Funding Agency for Science, Research and Technology - RCAAP Search Portal

location_country:
Italy
Austria
Sweden
Netherlands
Spain
Cyprus
Finland
France
Poland
Greece
Lithuania
Malta
Norway
Belgium
Portugal
Estonia
Germany
United Kingdom

location_facility: "Mitera" General Maternity and Pediatric Clinic

location_facility: Complexo Hospitalario Universitario de Vigo

location_facility: 2nd Dept of Neonatalogy, Aristole University of Thessaloniki

location_facility: James Cook University Hospital, Middlesborough

location_facility: Universitäts klinik für Kinder-und Jugenheilkunde Wien

location_facility: Departement of Neonato- logy Medical University in Wrocław

location_facility: Academic medical Center Amsterdam - Emma Children's Hospital

location_facility: Complexo Hospitalario Universitario de Santiago

location_facility: Evelina Children's Hospital, Guy's and St Thomas' NHS Foundation Trust PICU

location_facility: Northampton General Hospital Neonatal Unit

location_facility: Hospital General Universitario Gregorio Marañón

location_facility: UO Neonatologia e TIN Ospedale Santa Chiara

location_facility: IN Ospedale Macedonio Melloni Milano-AO Fatebenefratellied Oftalmico

location_facility: 1st Dept of Neonatalogy, Aristole University of Thessaloniki

location_facility: U.O.Patologia e Terapia Intensiva Neonatale AOUI Borgo Roma

location_facility: UO TIN Neonatologia AOU Sant'Orsola Malpighi

location_facility: Department of Paediatric and Adolescent Medicine University Hospital Erlangen

location_facility: Children's Memorial Health Institute Warsaw

location_facility: Complexo Hospitalario Universitario de A Coruña

location_facility: Karolinska University Hospital (Stockholm)

location_facility: Great Ormond Street Hospital for Sick Children PICU

location_facility: Great Western Hospitals NHS Foundation Trust

location_facility: U.O. di Neonatologia e PatNeo con T.I. - Istituti Ospitalieri

location_facility: Hospital Universitario Marqués de Valdecilla

location_facility: Hospital Universitario Central de Asturias

location_facility: Patologia Neonatale Ospedale S.M.Misericordia

location_facility: University Hospital Utrecht - Wilhelmina Children's Hospital

location_facility: Centre Hospitalier Régional de la Citadelle

location_facility: Jessop Wing, Sheffield Teaching Hospitals NHS Trust

location_facility: Universitäts-klinik für Kinder- und Jugendheilkunde Innsbruck

location_facility: Azienda Ospedaliera Universitaria di Sassari

location_facility: Blackpool Teaching Hospital Foundation Trust

location_facility: TIN Centro IRCSS Ca Granda-Policlinico Osp.Maggiore Mangiagalli LI

location_facility: Hospital Universitario Principe de Asturias

location_facility: Hospital Universitari i Politecnic La Fe

location_facility: Department of obstetric and gynecology, medical University of Warsaw

location_facility: Royal Devon and Exeter NHS Foundation Trust

location_facility: University Hospital Of North Staffordshire NHS Trust

location_facility: Department of Anesthesiology and Intensive Care, Tallinn Children's Hospital

location_facility: Paediatric Intensive Care Unit, Clinic of Anaesthesiology and Intensive Care, Tartu University Clinics

location_facility: Department of Neonatology Lithuanian University of Health Sciences,

location_facility: University Hospital of South Manchester, Wythenshawe

location_facility: Neonatal Intensiv Care Unit, Arch. Makarios Hospital

location_facility: Klinik fUr Kinder und Jugendliche Sozialstiftung Bamberg

location_facility: Southport & Ormskirk & District General Hospital Neonatal Unit

location_facility: York Teaching Hospital NHS Foundation Trust

location_facility: Terapia Intensiva Neonatale e Pediatrica

location_facility: Isala Clinics Zwolle - Amalia Children's Hospital

location_facility: Universitäts-klinik für Kinder und Jugendheilkunde Salzburg

location_facility: TIN/Neonatologia- fondazione MBBM- H San Gerardo

location_facility: TIN E Patologia Neonatale Dip. di Salute della donna e del bambino- Università di Padova

location_facility: Oslo University Hospital - Rikshospitalet


title: GLORIA - AF: Global Registry on Long-Term Oral Anti-thrombotic TReatment In PAtients With Atrial Fibrillation (Phase II/III - EU/EEA Member States)

summary: In this part of the Registry Program patients with non-valvular atrial fibrillation (AF) at risk for stroke are enrolled to characterize the target population and to collect real world data on important outcome events. For administrative purposes the study is divided into two protocol numbers: 1160.129 for non-EU (European Union) and non-EEA (European Economic Area) countries, and 1160.136 for EU and EEA countries. The total number of patients enrolled in both protocols is estimated to be 48,000 patients, and all these patients will be included in the data analysis for study 1160.129.

ReferenceCitation: Ntaios G, Huisman MV, Diener HC, Halperin JL, Teutsch C, Marler S, Gurusamy VK, Thompson M, Lip GYH, Olshansky B; GLORIA-AF Investigators. Anticoagulant selection in relation to the SAMe-TT(2)R(2) score in patients with atrial fibrillation: The GLORIA-AF registry. Hellenic J Cardiol. 2021 Mar-Apr;62(2):152-157. doi: 10.1016/j.hjc.2020.11.009. Epub 2020 Dec 15.

apc_source: doaj

family: Ntaios

full_name: George Ntaios

given: George

family: Huisman

full_name: Menno V. Huisman

given: Menno V.

family: Diener

full_name: Hans-Christoph Diener

given: Hans-Christoph

family: Halperin

full_name: Jonathan L. Halperin

given: Jonathan L.

family: Teutsch

full_name: Christine Teutsch

given: Christine

family: Marler

full_name: Sabrina Marler

given: Sabrina

family: Gurusamy

full_name: Venkatesh K. Gurusamy

given: Venkatesh K.

family: Thompson

full_name: Milla Thompson

given: Milla

family: Lip

full_name: Gregory Y.H. Lip

given: Gregory Y.H.

family: Olshansky

full_name: Brian Olshansky

given: Brian

family: Abban

full_name: Dzifa Wosornu Abban

given: Dzifa Wosornu

family: Abdul

full_name: Nasser Abdul

given: Nasser

family: Abud

full_name: Atilio Marcelo Abud

given: Atilio Marcelo

family: Adams

full_name: Fran Adams

given: Fran

family: Addala

full_name: Srinivas Addala

given: Srinivas

family: Adragão

full_name: Pedro Adragão

given: Pedro

family: Ageno

full_name: Walter Ageno

given: Walter

family: Aggarwal

full_name: Rajesh Aggarwal

given: Rajesh

family: Agosti

full_name: Sergio Agosti

given: Sergio

family: Agostoni

full_name: Piergiuseppe Agostoni

given: Piergiuseppe

family: Aguilar

full_name: Francisco Aguilar

given: Francisco

family: Linares

full_name: Julio Aguilar Linares

given: Julio Aguilar

family: Aguinaga

full_name: Luis Aguinaga

given: Luis

full_name: Eduardo Julián José Roberto Chuquiure Valenzuela

repository_institution: University of Modena and Reggio Emilia - IRIS UNIMORE

repository_institution: University of Turin - Institutional Research Information System University of Turin

repository_institution: University of Zurich - Zurich Open Repository and Archive

title: Anticoagulant selection in relation to the SAMe-TT2R2 score in patients with atrial fibrillation: The GLORIA-AF registry

ReferenceCitation: Huisman MV, Rothman KJ, Paquette M, Teutsch C, Diener HC, Dubner SJ, Halperin JL, Ma CS, Zint K, Elsaesser A, Lu S, Bartels DB, Lip GYH; GLORIA-AF Investigators. Two-year follow-up of patients treated with dabigatran for stroke prevention in atrial fibrillation: Global Registry on Long-Term Antithrombotic Treatment in Patients with Atrial Fibrillation (GLORIA-AF) registry. Am Heart J. 2018 Apr;198:55-63. doi: 10.1016/j.ahj.2017.08.018. Epub 2017 Aug 31.

repository_institution: University of Birmingham - University of Birmingham Research Portal

repository_institution: Aalborg Universitet - VBN Forskningsportal

repositories_institution: Aalborg Universitet - VBN Forskningsportal

ReferenceCitation: Huisman MV, Lip GY, Diener HC, Dubner SJ, Halperin JL, Ma CS, Rothman KJ, Teutsch C, Zint K, Ackermann D, Clemens A, Bartels DB. Design and rationale of Global Registry on Long-Term Oral Antithrombotic Treatment in Patients with Atrial Fibrillation: a global registry program on long-term oral antithrombotic treatment in patients with atrial fibrillation. Am Heart J. 2014 Mar;167(3):329-34. doi: 10.1016/j.ahj.2013.12.006. Epub 2013 Dec 19.

title: Design and rationale of Global Registry on Long-Term Oral Antithrombotic Treatment in Patients with Atrial Fibrillation: A global registry program on long-term oral antithrombotic treatment in patients with atrial fibrillation

location_country:
Greece
Romania
Belgium
Denmark
Croatia
France
Poland
Norway
Slovenia
Sweden
Netherlands
Bulgaria
Ireland
Portugal
Germany
United Kingdom
Italy
Austria
Czechia
Spain
Estonia
Latvia

location_facility: Hospital Universitario Virgen de la Arrixaca

location_facility: A.O.U. Senese Policlinico Santa Maria alle Scotte

location_facility: Azienda Sanitaria Ospedale S. Luigi Gonzaga

location_facility: UMHAT, Clinic of Cardiology, Stara Zagora

location_facility: Azienda Unità Sanitaria Locale di Reggio Emilia

location_facility: CHLO, EPE - Hospital S. Francisco Xavier

location_facility: Centro Hospitalar Universitário São João,EPE

location_facility: CAB Dascotte O, Cardio, St André lez Lille

location_facility: Multiprofile Hospital for Active Treatment, Sliven

location_facility: Med.Centre Diagnosis,Treatm&Prev Med.Cardiol.Dept, Bucharest

location_facility: Gesundheit Nord gGmbH | Klinikverbund Bremen

location_facility: Royal Bournemouth and Christchurch Hospital

location_facility: St. Antonius ziekenhuis, locatie Nieuwegein

location_facility: General Panarkadiko Hospital of Tripolis, Cardiology Clinic

location_facility: Univ. Hosp. Sisters of Mercy, Cardiology Dept., Zagreb

location_facility: University Multiprofile Hospital 'Alexandrovska', Sofia

location_facility: Policlinico Universitario Mater Domini, Universita di Catanzaro

location_facility: Cardiology Out-patient Clinic "Cardio-Plus", Radlin

location_facility: Clinical Hosp.Merkur,Clin.Internal Med,Cardiology Dep,Zagreb

location_facility: Umberto I Pol. di Roma-Università di Roma La Sapienza

location_facility: Universitätsklinikum Carl Gustav Carus Dresden

location_facility: KH d. Barmherzigen Brüder Wien, Neurologie

location_facility: Univ. Medical Centre Ljubljana, Dept. of Vascular Diseases

location_facility: HOP Sud Francilien, Cardio, Corbeil-Essonnes

location_facility: "Korgialeneio-Benakeio" Hellenic Red Cross Hospital

location_facility: Sydvestjysk Sygehus Esbjerg, Hjertemedicinsk afd.

location_facility: Azienda Ospedaliera Universitaria di Padova

location_facility: Evangelisches Elisabeth-Krankenhaus, Berlin Mitte

location_facility: Slaskie Center Heart Disease SUM,Cardiol.&Electr.Clin.Zabrze

location_facility: Centro Hospitalar da Cova da Beira Hospital Pêro da Covilhã

location_facility: General Hosp. Zadar, Clinic of Internal Med, Cardiology Dept

location_facility: Research Unit, Liverpool Heart and Chest Hospital

location_facility: A.O. Univ. Vittorio Ferrarotto S. Bambino

location_facility: Gemeinschaftspraxis Dr. med. J. Sek, Chemnitz

location_facility: General Hospital of Edessa, Cardiology Clinic

location_facility: Sykehuset Innlandet HF, Avd. Lillehammer

location_facility: Gen. Hosp. of Thessaloniki "Hippokation", Cardiology Clinic

location_facility: Polyclinic St. Luke, Cardiology Dept., Zagreb

location_facility: CAB Brunehaut M, Cardio, Clermont Ferrand

location_facility: Hospital General Universitario de Valencia

location_facility: Reg.Hosp, Intern.Med.Ward w/ Intensive Cardiol.Care, Opoczno

location_facility: MHAT "Tsaritsa Yoanna-ISUL" Clinic of Cardiology, Sofia

location_facility: HOP de la région d'Annecy, Cardio, Metz-Tessy

location_facility: Ordination Dr. Martin Koschutnik, Oberwart

location_facility: Asclepion Voulas Hospital, Cardiological Clinic

location_facility: Hospital Regional Universitario de Málaga

location_facility: Specialized Hosp.f.Active Treatment, Cardiology Dept, Yambol

location_facility: Nuovo Ospedale Civile S. Agostino-Estense

location_facility: Klinikum rechts der Isar der Technischen Universität München

location_facility: Azienda Complessa Ospedaliera Ospedale San Fiippo Neri

location_facility: Liepaja Regional Hospital, Therapy Department

location_facility: North Estonia Med.Centre,Internal Med.Clin/Cardiology,Tallin

location_facility: HOP Louis Pasteur, Cardio, Bagnols sur Ceze

location_facility: Ziekenhuis Oost-Limburg - Campus Sint-Jan

location_facility: Sotiria Hosp.,Hypertension Unit,3rd Clinic of Internal Med.

location_facility: Specialistic Cardiology&Hypertension Out-patient Clin,Kielce

location_facility: Individual Specialistic Private Practice,Dr.A.Tomasik,Zabrze

location_facility: MHAT "National Cardiology Hosp." Cardiology Dept., Sofia

location_facility: Hospital Universitario Marqués de Valdecilla

location_facility: CAB Houppe Nousse MP, Cardio, Thionville

location_facility: Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil gGmbH

location_facility: Diagnostic & Consultancy Center "Ascendent", Sofia

location_facility: Azienda Ospedaliera Universitaria Arcispedale Sant'Anna

location_facility: HOP de Courbevoie, Spécialités Med, Neuilly sur Seine

location_facility: Ospedale S.Maria della Misericordia, AO di Perugia

location_facility: HOP Privé de la Loire, Cardio, Saint Etienne

location_facility: MHAT "Deva Maria", Dept. of Cardiology, Burgas

location_facility: Individual Specialist.Private Practice Dr.W.Krysiak,Szczecin

location_facility: "Papageorgiou" General Hospital of Thessaloniki, B' Cardiolo

location_facility: HOP d'Aix en Provence, cardio, Aix-en-Provence

location_facility: Specialist Out-patient Clinics 'Na Gornej',Cieszyn

location_facility: CAB Phan Cao Phai, Cardio, Levallois Perret

location_facility: MHAT "Dr.Stambolski", Cardiology&Intensiv Care Dept,Kazanlak

location_facility: Az.Osp. Universitaria "Ospedali Riuniti"

location_facility: University General Hospital of Heraklion

location_facility: Osp. Guglielmo da Saliceto AUSL di Piacenza

location_facility: Klinikum der Stadt Ludwigshafen am Rhein gGmbH

location_facility: Praxis Dr.med. Jens Taggeselle, Markkleeberg

location_facility: Emergency University Hospital, Bucharest

location_facility: Thalassoterapia,Rehab.of heart&lung,Cardiology Clin, Opatija

location_facility: Cardiology Private Practice, Roznov pod Radhostem

location_facility: HOP Raincy Montfermeil, Cardio, Montfermeil

location_facility: Ruhrlandklinik, Westdeutsches Lungenzentrum am Universitätsklinikum Essen gGmbH

location_facility: Ospedale S. Maria di Ca' Foncello Azienda ULSS9 TREVISO

location_facility: Univ. Hosp. Sisters of Mercy, Neurology Clinic, Zagreb

location_facility: Klinik Pirawarth, Therapie und Rehabilitation, Bad Pirawarth

location_facility: MHAT, Fourth Dept. of Internal Medicine, Rousse

location_facility: Hospital General Universitario de Alicante

location_facility: HOP William Morey, Cardio, Chalon-Sur-Saône

location_facility: CLI les Cedres, Cardio, Brive La Gaillarde

location_facility: Private Practice of Heart Diseases Malgorzata Lelonek,Lodz

location_facility: Ospedale Santa Corona Azienda Sanitaria Locale n.2 Savonese

location_facility: Praxis für Herz-Kreislauf-Erkrankungen Zeulenroda-Greiz

location_facility: METC Academisch Ziekenhuis Maastricht/Universiteit van Maastricht