title: Combined Phase 2b/3, Double-Blind, Randomized, Placebo-Controlled Studies Evaluating the Efficacy and Safety of Filgotinib in the Induction and Maintenance of Remission in Subjects With Moderately to Severely Active Ulcerative Colitis

acronym: SELECTION

summary:
The primary objectives of this study are to evaluate the efficacy of filgotinib in the induction and maintenance treatment of moderately to severely active ulcerative colitis (UC) in participants who are biologic-naive and biologic-experienced.

Participants who complete the study, or met protocol specified efficacy discontinuation criteria will have the option to enter a separate, long-term extension (LTE) study (Gilead Study GS-US-418-3899: NCT02914535).

ReferenceCitation: Feagan BG, Danese S, Loftus EV Jr, Vermeire S, Schreiber S, Ritter T, Fogel R, Mehta R, Nijhawan S, Kempiński R, Filip R, Hospodarskyy I, Seidler U, Seibold F, Beales ILP, Kim HJ, McNally J, Yun C, Zhao S, Liu X, Hsueh CH, Tasset C, Besuyen R, Watanabe M, Sandborn WJ, Rogler G, Hibi T, Peyrin-Biroulet L. Filgotinib as induction and maintenance therapy for ulcerative colitis (SELECTION): a phase 2b/3 double-blind, randomised, placebo-controlled trial. Lancet. 2021 Jun 19;397(10292):2372-2384. doi: 10.1016/S0140-6736(21)00666-8. Epub 2021 Jun 3.

family: Feagan

full_name: Brian G Feagan

given: Brian G

family: Danese

full_name: Silvio Danese

given: Silvio

family: Loftus

full_name: Edward V Loftus

given: Edward V

suffix: Jr

family: Vermeire

full_name: Séverine Vermeire

given: Séverine

family: Schreiber

full_name: Stefan Schreiber

given: Stefan

family: Ritter

full_name: Timothy Ritter

given: Timothy

family: Fogel

full_name: Ronald Fogel

given: Ronald

family: Mehta

full_name: Rajiv Mehta

given: Rajiv

family: Nijhawan

full_name: Sandeep Nijhawan

given: Sandeep

family: Kempiński

full_name: Radosław Kempiński

given: Radosław

family: Filip

full_name: Rafał Filip

given: Rafał

family: Hospodarskyy

full_name: Ihor Hospodarskyy

given: Ihor

family: Seidler

full_name: Ursula Seidler

given: Ursula

family: Seibold

full_name: Frank Seibold

given: Frank

family: Beales

full_name: Ian L P Beales

given: Ian L P

family: Kim

full_name: Hyo Jong Kim

given: Hyo Jong

family: McNally

full_name: John McNally

given: John

family: Yun

full_name: Chohee Yun

given: Chohee

family: Zhao

full_name: Sally Zhao

given: Sally

family: Liu

full_name: Xiaopeng Liu

given: Xiaopeng

family: Hsueh

full_name: Chia-Hsiang Hsueh

given: Chia-Hsiang

family: Tasset

full_name: Chantal Tasset

given: Chantal

family: Besuyen

location_country:
Malaysia
Greece
Romania
Australia
Belgium
Russian Federation
Taiwan
Ukraine
India
Croatia
France
Japan
Poland
Slovakia
Norway
Argentina
Canada
Korea, Republic of
South Africa
Sweden
Hong Kong
Netherlands
Switzerland
Bulgaria
Singapore
Hungary
Ireland
Portugal
Germany
United States
United Kingdom
Italy
Austria
Serbia
Mexico
Czechia
Israel
Georgia
New Zealand
Spain

location_facility: Hyogo College of Medicine College Hospital

location_facility: Centralny Szpital Kliniczny Ministerstwa Spraw Wewnetrznych i Administacji w Warszawie

location_facility: Gastroenterologische Praxis Balsiger, Seibold und Partner

location_facility: Massachusetts General Hospital - Crohn's and Colitis Center

location_facility: Kitakyushu City Hospital Organization Kitakyushu Municipal Medical Center

location_facility: State Budgetary Healthcare Institution of the Novosibirsk Region "State Novosibirsk Regional Clinical Hospital"

location_facility: Centrum Opieki Zdrowotnej Orkan-Med Stec-Michalska Sp.J.

location_facility: H-T.Centrum Medyczne Spolka z Ograniczona Odpowiedzialnoscia Sp.K.

location_facility: Shiga University of Medical Science Hospital

location_facility: Gastroenterology Research of San Antonio

location_facility: Gastroenterology Associates Of Tidewater

location_facility: Fargo Gastroenterology and Hepatology Clinic

location_facility: Uniwersytecki Szpital Kliniczny w Bialymstoku, Klinika Gastroenterologii i Chorob Wewnetrznych

location_facility: Vanderbilt University Medical Center - IBD Clinic

location_facility: Oxford University Hospitals NHS Foundation Trust

location_facility: ISCARE a.s. (Klinicke centrum ISCARE), Klinicke a vyzkumne centrum pro strevni zanety

location_facility: Centre Hospitalier Regional Universitaire de Lille

location_facility: University of Wisconsin Hospital & Clinics

location_facility: Cambridge University Hospital NHS Foundation Trust

location_facility: Centre Hospitalier Universitaire de Rennes - Hopital Pontchaillou

location_facility: GASTROMED Kopon, Zmudzkinski i Wspolnicy Sp. j. Specjalistyczne Centrum Gastrologii i Endoskopii

location_facility: PCR-Phylasis Clinicas Research S. de R.L. de C.V.

location_facility: Gabinet Lekarski Dr. Hab. N. Med. Bartosz Korczowski

location_facility: Debreceni Egyetem Klinikai Kozpont, II. sz. Belgyogyaszati Klinika, Gasztroenterologia

location_facility: Odesa Clinical Railway Hospital Branch of "Healthcare Center" of Public joint stock company "Ukrainian Railway"

location_facility: Federal State Budgetary Institution of Science Federal Research Center of Nutrition, Biotechnology and Food Safety

location_facility: Institute of Gastroenterology & Liver Disease, Sunshine Hospitals

location_facility: Baylor College of Medicine- Baylor Medical Center

location_facility: State Budgetary Institution of Health Irkustsk Order "Badge of Honor" Regional Clinical Hospital

location_facility: Toronto Digestive Disease Associates Inc.

location_facility: National Hospital Organization Sendai Medical Center

location_facility: University of Iowa Hospitals and Clinics

location_facility: Universitatsklinikum Ulm, Zentrum Fur Innere Medizin

location_facility: University of Calgary, Heritage Medical Research Clinic

location_facility: Municipal Health Care Institution "Kharkiv City Clinical Hospital #2 named after prof. O. O. Shalimov", Proctology Department

location_facility: MGG Group Co., Inc., Chevy Chase Clinical Research

location_facility: Instituto de Investigaciones Clinicas Mar del Plata

location_facility: Oblastni nemocnice Mlada Boleslav, a.s., nemocnice Stredoceskeho kraje, Gastroenterologicke oddeleni

location_facility: State Budgetary Institution of Health of Novosibirsk Region "City Clinical Hospital #12"

location_facility: Regional Municipal Institution "Chernivtsi Regional Clinical Hospital", Surgical Department

location_facility: Division of Gastroenterology, Department of Medicine, Samsung Medical Center

location_facility: Centre Hospitalier Universitaire de Lyon Sud

location_facility: NYU Langone Long Island Clinical Research Associates

location_facility: Municipal Non-profit Enterprise "Consultative and Diagnostic Center" of Pechersk District of Kyiv, Therapy Department

location_facility: Ivanto-Frankivsk Central City Clinic Hospital, Therapy Department #1. State Higher Education Institution Ivano-Frankivsk National

location_facility: Treatment and Diagnostic Center of Private Enterprise of Private Production Company "Acinus"

location_facility: Niepubliczny Zaklad Opieki Zdrowotnej ALL-MEDICUS

location_facility: Washington University School of Medicine

location_facility: Centre Hospitalier Chretien (CHC) - Clinique Saint-Joseph

location_facility: Grant Medical Foundation Ruby Hall Clinic

location_facility: Klinikum der Universitat Munchen - Grosshadern

location_facility: Vestre Viken Hospital Trust, Baerum Hospital

location_facility: Vinnytsia Regional Clinical Hospital of War Veterans, Therapy Department #1

location_facility: M.I. Pyrogov Vinnytsia Regional Clinical Hospital, Gastroenterology Department

location_facility: Ospedale Clinicizzato SS. Annunziata - Dipartimento di Medicina

location_facility: Twoja Przychodnia-Szczecinskie Centrum Medyczne

location_facility: State Budgetary Healthcare Institution of Nizhny Novgorod Region "Nizhny Novgorod Regional Clinical Hospital n.a. N.A.

location_facility: M S Ramaiah Medical College and Hospital

location_facility: Kitasato University Hospital, THE KITASATO INSTITUTE

location_facility: Municipal Institution of Health Care "Regional Hospital of War Veterans", Therapeutic Department No1

location_facility: State Budgetary Healthcare Institution of Moscow "City Clinical Hospital # 24 of Healthcare Department of Moscow"

location_facility: DRK Kliniken Berlin - Westend - Klinik fuer Innere Medizin

location_facility: Cabinet Medical Individual Dr Tirnaveanue Amelita, Gastroenterologie

location_facility: The Catholic University of Korea, St. Vincent's Hospital

location_facility: "Scientific Research Centre ECO-safety" LLC

location_facility: Treatment and Prevention Interdistrict Institution "Smolenskie kliniki" LLC

location_facility: Municipal Institution "Zaporizhzhya Regional Clinical Hospital" of Zaporizhzhya Regional Council

location_facility: Clinical Associates in Research Therapeutics of America, LLC

location_facility: Great Lakes Gastroenterology Research, LLC

location_facility: CHU de Clermont-Ferrand - Hopital d'Estaing

location_facility: Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital

location_facility: Municipal Institution "Cherkasy Regional Hospital of Cherkasy Regional Council", Gastroenterology Department

location_facility: University Kebangsaan Malaysia Medical Centre

location_facility: UOC Gastroenterologia ed Endoscopia Digestiva

location_facility: St Helens and Knowsley Teaching Hospitals NHS Trust

location_facility: Ternopil University Hospital, Regional Center of Gastroenterology with Hepatology

location_facility: Azienda Ospedaliero-Universitaria Pisana - Presidio Ospedaliero Cisanello

location_facility: Yokohama Health Medicine Association Kannai Suzuki Clinic

location_facility: CHU de Dijon Bourgogne - Hopital Francois Mitterand

location_facility: Ltd. Unimed Kakheti - Telavi Referral Hospital

location_facility: Yonsei University Health System, Severance Hospital

location_facility: Medical Hospital, Tokyo Medical and Dental University

location_facility: Southampton National Institute for Health Research, Wellcome Trust Clinical Research Facility

location_facility: University of Miami Crohn's and Colitis Center

location_facility: State Budgetary Healthcare Institution "Chelyabinski Regional Clinical Hospital"

location_facility: Chang Gung Medical Foundation, Chang Gung Memorial Hospital, Linkou Branch

location_facility: Hospital da Senhora da Oliveira Guimaraes, E.P.E.

location_facility: General Hospital of Nikaias "Agios Pentelleimon", Gastroenterology Department

location_facility: National Hospital Organization Takasaki General Medical Center

location_facility: Glasgow Clinical Research Facility - Queen Elizabeth University Hospital

location_facility: Clinical Research Center Spolka z organiczna odpowiedzialnoscia Medic-R Sp. k.

location_facility: University of Louisville, Clinical Trials Unit

location_facility: Bekes Megyei Kosponti Korhaz, Dr. Rethy Pal Tagkorhaz, IV. Belgyogyaszat - 2. Gasztroenterologia

location_facility: Hamilton Health Sciences Corporation, McMaster University Medical Centre

location_facility: Colo-proctology Center Matsushima Clinic

location_facility: Saint Petersburg State Budgetary Healthcare Institution "City Polyclinic #38"

location_facility: Endocsopia Digestiva Centralizzata - ASST Fatebenefratelli Sacco, Ospedale Fatebenefratelli e Oftalmico

location_facility: Gastroenterology Associates of Central Georgia, LLC

location_facility: VGM Hospital Institute of Gastroenterology

location_facility: State Autonomous Health Institution of the Tyumen Region "Multidisciplinary Consultative and Diagnostic Center"

location_facility: General Hospital of Athens "Hippokratio", 2nd Internal Medicine Clinic of Athens University, Hepato-gastroenterology Unit

location_facility: Lokmanya Tilak Municipal General Hospital

location_facility: KM Management, s.r.o., Gastroenterologicke a hepatologicke centrum Nitra

location_facility: Digestive Health Specialists of the Southeast

location_facility: Niepubliczny Zaklad Opieki Zrodotnej VIVAMED Jadwige Miecz

location_facility: Hospital Universitario Central de Asturias

location_facility: L.T. Mala State Institution "National Institute of Therapy of National Academy of Medical Sciences of Ukraine"

location_facility: The University of Texas Health Science Center at Houston

location_facility: Gastroenterology Associates of Orangeburg

location_facility: Norfolk and Norwich University Hospital NHS Foundation Trust

location_facility: Del-pesti Centrumkorhaz - Orszagos Hematologiai es Infektologiai Intezet, Kozponti Felnott Szakrendelo

location_facility: Centrum Innowacyjnych Terapii Sp. z o.o.

location_facility: Spitalul Clinic Colentina - Sectia de Spitulal Clinic Colentina, Gastroenterologie

location_facility: Hokkaido P.W.F.A.C Sapporo-Kosei General Hospital

location_facility: Karolina Korhaz es Rendelointezet, Altalanos Belgyogyaszat-Gasztroenterologia

location_facility: University Hospital, Kyoto Prefectural University of Medicine

location_facility: State Budgetary Healthcare Institution of Moscow Region "Moscow Regional Clinical Research Institute n.a. M.F. Vladimirskiy"

location_facility: Bay of Plenty District Health Board - Tauranga Hospital


title: A Randomized, Double-blinded, Phase III Study of Atezolizumab Versus Placebo in Patients With Late Relapse of Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer Treated by Platinum-based Chemotherapy and Bevacizumab

acronym: ATALANTE

summary: This is a phase III, randomized, double-blinded, comparative, multi-centre study to assess the efficacy of atezolizumab in combination with platinum-based chemotherapy plus bevacizumab administered concurrent to chemotherapy and in maintenance, in patients presenting epithelial ovarian cancer (including patients with primary peritoneal and / or fallopian tube adenocarcinoma) who have platinum-sensitive relapse (platinum-free interval > 6 months).

study_start_date_type: Actual

status: Active, not recruiting

study_completion_date_type: Anticipated

study_type: Interventional

design_allocation: Randomized

primary_purpose: Treatment

enrollment_type: Actual

lead_sponsor: ARCAGY/ GINECO GROUP

location_country: Austria France Czechia Israel Belgium Spain Germany

location_facility: Groupe Hospitalier Mutualiste de Grenoble

location_facility: CHU Nîmes - Institut de Cancérologie du Gard

location_facility: Hospital Universitari de Girona ICO Girona (Dr. Josep Trueta)

location_facility: Hospital Central Universitario Virgen de la Arrixaca

location_facility: Klinikum der Universität München - LMU, Campus Großhadern

location_facility: Institut de Cancérologie Strasbourg Europe (ICANS)

location_facility: Centre Hospitalier Départemental Les Oudairies

location_facility: Groupe Hospitalier Diaconesses-Croix Saint Simon

location_facility: Kliniken Essen Mitte, Evang. Huyssens-Stiftung

location_facility: ICL Institut de Cancérologie de Lorraine

location_facility: Klinikum rechts der Isar, Technischen Universität München

location_facility: Hôpital de la Milétrie - Centre Hospitalier Universitaire de Poitiers - Pôle Régional de Cancérologie

location_facility: Krankenhaus der Barmherzigen Brüder Graz

location_facility: Charité, Campus Virchow-Klinikum, Universitätsmedizin Berlin

location_facility: Sainte-Catherine Institut du Cancer Avignon-Provence

location_facility: Hôpital Michallon - Centre Hospitalier Universitaire de Grenoble

location_facility: Hospital Universitario Clínico San Carlos

location_facility: Institut Curie - Hopital Claudius Régaud

intervention_type: Drug

lead_sponsor_type: industriel

status_simplified: Ongoing


title: An International Survey on Aminoglycoside Practices in Critically Ill Patients: AMINO III Survey

summary: This is an international observational cohort study on current aminoglycoside practices in intensive care units. Clinical and demographic data, dosing and therapeutic drug monitoring data will be collected during the first week of aminoglycoside (tobramycin, amikacin or gentamicin) administration in different countries over a year. A minimum of ten consecutive patients will be enrolled at each site.

status: Completed

study_completion_date_type: Actual

study_type: Observational

time_perspective: Prospective

ipd_sharing: No

lead_sponsor: Centre Hospitalier Universitaire de Nīmes

location_country:
Chile
France
Greece
Australia
United Kingdom

location_facility: Centre Hospitalier de Toulon, Hopital Sainte Musse

location_facility: Centre Hospitalier La Rochelle-Hopital Saint Louis

location_facility: University Critical Care Department Aghioi Anargyroi Hospital

intervention_type: Other

lead_sponsor_type: academique

status_simplified: Completed


title: SPECTA: Screening Cancer Patients for Efficient Clinical Trial Access

acronym: SPECTA

summary: SPECTA is a quality assured platform for collecting clinicopathologically annotated biological material, imaging data, operative images, environmental assessment, questionnaires as well as patient-reported outcomes from cancer patients to support biospecimen-based translational research and clinical cancer research, including biomarker discovery to improve the understanding of tumor biology and cancer patients care.

status: Recruiting

enrollment_type: Anticipated

lead_sponsor: European Organisation for Research and Treatment of Cancer - EORTC

location_country:
Italy
Austria
Switzerland
Netherlands
Spain
Cyprus
Croatia
Czechia
France
Greece
Lithuania
Poland
Belgium
Portugal
Estonia
Germany
United Kingdom

location_facility: Hopital Nord Franche-Comte - Site du Mittan

location_facility: CHU Lyon - Hopital neurologique Pierre Wertheimer

location_facility: Institut de Cancerologie de la Loire Lucien Neuwirth

location_facility: Clinique Mutualiste de l'Estuaire - Centre d'oncologie

location_facility: Assistance Publique - Hopitaux de Marseille - Hopital Nord

location_facility: Hospital Clinico Universitario De Valencia

location_facility: Assistance Publique - Hopitaux de Paris - Hopital Saint Antoine

location_facility: CHU de Grenoble - La Tronche - Hôpital A. Michallon

location_facility: Charite - Universitaetsmedizin Berlin - Campus Virchow-Klinikum

location_facility: Medical University Vienna - General Hospital AKH

location_facility: Velindre NHS Trust - Velindre Cancer Centre

location_facility: University Hospitals Coventry and Warwickshire NHS Trust - University Hospital

location_facility: Institut de Cancerologie de l'Ouest (ICO) - Centre Paul Papin

location_facility: Cambridge University Hospital NHS - Addenbrookes Hospital

location_facility: Assistance Publique - Hopitaux de Paris - La Pitie Salpetriere

location_facility: NHS Greater Glasgow and Clyde - Beatson West of Scotland Cancer Centre - Gartnavel General Hospital

location_facility: Hopitaux Universitaires - Institut Jules Bordet

location_facility: Assitance Publique - Hopitaux de Paris - Hopital Saint-Louis

location_facility: Centre Hospitalier Regional De La Citadelle

location_facility: Hospital Infantil Universitario Nino Jesus

location_facility: Leeds Teaching Hospitals NHS Trust - St. James's University Hospital

location_facility: Institut de Cancerologie Strasbourg Europe (formar Paul Strauss)

location_facility: Instituto Portugues de Oncologia do Porto

location_facility: Institut de Cancerologie de l'Ouest (ICO) - Centre Rene Gauducheau

location_facility: Hospital Clinic Universitari de Barcelona

location_facility: North Estonia Medical Centre - Mustamäe unit

location_facility: Radboud University Medical Center Nijmegen

location_facility: IRCCS Azienda Ospedaliera Universitaria San Martino "IST" Istituto Nazionale per la Ricerca sul Cancro

location_facility: Universita Di Torino - Ospedale S. Luigi Gonzaga

location_facility: Ospedale S. Luigi Gonzaga - Universita Di Torino

location_facility: Betsi Cadwaladr University Health Board - Glan Clwyd District General Hospital

location_facility: Azienda Unita Locale Socio-Sanitaria N. 9-Mater Salutis Hospital

location_facility: Azienda Ospedaliera Città della Salute e della Scienza di Torino - Ospedale Sant'Anna

location_facility: Maria Sklodowska-Curie Memorial Cancer Centre

location_facility: Lithuanian Oncology Center-Nat. Cancer Inst

location_facility: Maria S. Curie Memorial Institute-Gliwice Branche

location_facility: Azienda Ospedaliera Città della Salute e della Scienza di Torino - Ospedale Molinette

location_facility: University Hospitals Birmingham NHS Foundation Trust (UHB) - UHB-Queen Elisabeth Medical Centre

location_facility: UniversitaetsSpital Zurich - Neurology Clinic

intervention_type: Genetic


type: EudraCT Number

title: A Prospective Evaluation of Natriuretic Peptide Based Referral of CHF Patients in Primary Care

acronym: PREFER

summary: This low interventional study, whose unique intervention was to measure the blood level of a biomarker called NT-proBNP in chronic heart failure patients daily followed-up by Primary Care Physicians (PCPs) in Europe, assessed if the cardiologist referral guided by NT-proBNP measurement in patients who were currently judged by PCPs as being stable, would lead to optimization of HF treatment, defined in adherence to treatment recommendations of the current European Society of Cardiology guidelines for the treatment of heart failure.

primary_purpose: Other

ipd_sharing: Yes

ipd_sharing_description: Novartis is committed to sharing with qualified external researchers, access to patient-level data and supporting clinical documents from eligible studies. These requests are reviewed and approved by an independent review panel on the basis of scientific merit. All data provided is anonymized to respect the privacy of patients who have participated in the trial in line with applicable laws and regulations. This trial data availability is according to the criteria and process described on www.clinicalstudydatarequest.com

lead_sponsor: Novartis Pharmaceuticals

location_country:
Italy
Spain
Cyprus
Croatia
France
Lithuania
Israel
Poland
Malta
Hungary
Belgium
Norway
Russian Federation
Portugal
Estonia
Denmark
Slovenia
Latvia

intervention_type: Procedure


title: A NOVEL Observational longiTudinal studY on Patients With Asthma and/or COPD to Describe Patient Characteristics, Treatment Patterns and the Burden of Illness Over Time and to Identify Phenotypes and Endotypes.

acronym: NOVELTY

summary: The NOVEL Observational longiTudinal studY (NOVELTY) is an observational study of obstructive lung disease and is a multi-country, multi-centre, prospective, longitudinal cohort study which will recruit patients with a diagnosis, or suspected diagnosis, of asthma and/or Chronic Obstructive Pulmonary Disease (COPD). Patients will undergo clinical assessments and receive standard medical care as determined by their treating physician. Patients enrolled in NOVELTY will be followed up yearly by their treating physician for a total duration of three years. In addition, patients will be followed up remotely every 3 months. The NOVELTY study will collect data currently lacking to allow for multinational data collection to fill regional/local gaps and improve comparability across regions.

ReferenceType: derived

ReferenceCitation: Reddel HK, Vestbo J, Agustí A, Anderson GP, Bansal AT, Beasley R, Bel EH, Janson C, Make B, Pavord ID, Price D, Rapsomaniki E, Karlsson N, Finch DK, Nuevo J, de Giorgio-Miller A, Alacqua M, Hughes R, Müllerová H, Gerhardsson de Verdier M; NOVELTY study investigators. Heterogeneity within and between physician-diagnosed asthma and/or COPD: NOVELTY cohort. Eur Respir J. 2021 Sep 23;58(3). pii: 2003927. doi: 10.1183/13993003.03927-2020. Print 2021 Sep.

family: Reddel

full_name: Helen K Reddel

given: Helen K

sequence: first

family: Vestbo

full_name: Jørgen Vestbo

given: Jørgen

sequence: additional

family: Agustí

full_name: Alvar Agustí

given: Alvar

family: Anderson

full_name: Gary P Anderson

given: Gary P

family: Bansal

full_name: Aruna T Bansal

given: Aruna T

family: Beasley

full_name: Richard Beasley

given: Richard

family: Bel

full_name: Elisabeth H Bel

given: Elisabeth H

family: Janson

full_name: Christer Janson

given: Christer

family: Make

full_name: Barry Make

given: Barry

family: Pavord

full_name: Ian D Pavord

given: Ian D

family: Price

full_name: David Price

given: David

family: Rapsomaniki

full_name: Eleni Rapsomaniki

given: Eleni

family: Karlsson

full_name: Niklas Karlsson

given: Niklas

family: Finch

full_name: Donna K Finch

given: Donna K

family: Nuevo

full_name: Javier Nuevo

given: Javier

family: de Giorgio-Miller

full_name: Alex de Giorgio-Miller

given: Alex

family: Alacqua

full_name: Marianna Alacqua

given: Marianna

family: Hughes

full_name: Rod Hughes

given: Rod

family: Müllerová

full_name: Hana Müllerová

given: Hana

family: Gerhardsson de Verdier

full_name: Maria Gerhardsson de Verdier

given: Maria

bso_classification: Medical research

datasource: user

genre: journal-article

genre_raw: journal-article

journal_name: European Respiratory Journal

oa_colors: green hybrid

oa_host_type: publisher;repository

evidence: open (via free pdf)

host_type: publisher

license_normalized: no license

version: publishedVersion

evidence: oa repository (via OAI-PMH doi match)

repository_institution: The University of Manchester - Research Explorer

repository_institution: Aberdeen University - Aberdeen University Research Archive

repositories:
PubMed Central
Pure (Denmark)
aura.abdn.ac.uk

ReferenceCitation: Karlsson N, Atkinson MJ, Müllerová H, Alacqua M, Keen C, Hughes R, Janson C, Make B, Price D, Reddel HK. Validation of a diagnosis-agnostic symptom questionnaire for asthma and/or COPD. ERJ Open Res. 2021 Feb 1;7(1). pii: 00828-2020. doi: 10.1183/23120541.00828-2020. eCollection 2021 Jan.

ReferenceCitation: Reddel HK, Gerhardsson de Verdier M, Agustí A, Anderson G, Beasley R, Bel EH, Janson C, Make B, Martin RJ, Pavord I, Price D, Keen C, Gardev A, Rennard S, Sveréus A, Bansal AT, Brannman L, Karlsson N, Nuevo J, Nyberg F, Young SS, Vestbo J. Prospective observational study in patients with obstructive lung disease: NOVELTY design. ERJ Open Res. 2019 Feb 1;5(1). pii: 00036-2018. doi: 10.1183/23120541.00036-2018. eCollection 2019 Feb.

repository_institution: University of Melbourne - Minerva Access

repository_institution: Uppsala University - Uppsala University Publications

evidence: oa repository (via OAI-PMH title and first author match)

repository_institution: University of Oxford - Oxford University Research Archive (ORA)

location_country:
Italy
Brazil
United States
Sweden
Mexico
Netherlands
Germany
Spain
France
Japan
Norway
Argentina
Australia
China
Denmark
Canada
United Kingdom
Korea, Republic of
Colombia


title: An Open-label, Prospective, Non-randomized, Multicenter Study to Evaluate Clear Skin Effect on Health Related Quality of Life Outcomes at 16 and 52 Weeks in Patients With Moderate to Severe Plaque Psoriasis Treated With Secukinumab 300 mg s.c. With or Without Previous Exposure to Systemic Therapy.

acronym: PROSE

summary: Study of effects of secukinumab 300 mg s.c. on quality of life (QoL) in psoriasis in patients with or without prior exposure to systemic therapy.

ReferenceCitation: da Silva N, Sommer R, Ortmann CE, Jagiello P, Bachhuber T, Augustin M. Secukinumab effects on disease burden, patient needs and benefits, and treatment satisfaction in patients with plaque psoriasis across European regions: patient perspective data from the PROSE study. J Eur Acad Dermatol Venereol. 2021 Nov;35(11):2241-2249. doi: 10.1111/jdv.17525. Epub 2021 Jul 31.

name: Institute for Health Services Research in Dermatology and Nursing (IVDP) University Medical Center Hamburg‐Eppendorf Hamburg Germany

family: Silva

full_name: N. Silva

given: N.

family: Sommer

full_name: R. Sommer

given: R.

family: Ortmann

full_name: C.‐E. Ortmann

family: Jagiello

full_name: P. Jagiello

given: P.

family: Bachhuber

full_name: T. Bachhuber

given: T.

family: Augustin

full_name: M. Augustin

given: M.

journal_name: Journal of the European Academy of Dermatology and Venereology

oa_host_type: publisher

evidence: open (via crossref license)

license: cc-by-nc-nd

license_normalized: cc-by-nc-nd

publisher: Wiley

publisher_dissemination: Wiley

publisher_group: Wiley

publisher_normalized: Wiley

ipd_sharing_description:
Novartis is committed to sharing with qualified external researchers, access to patient-level data and supporting clinical documents from eligible studies. These requests are reviewed and approved by an independent review panel on the basis of scientific merit. All data provided is anonymized to respect the privacy of patients who have participated in the trial in line with applicable laws and regulations.

This trial data availability is according to the criteria and process described on www.clinicalstudydatarequest.com

location_country:
Italy
United Kingdom
Spain
France
Czechia
Bulgaria
Greece
Israel
Lithuania
Poland
Belgium
Romania
Slovakia
Portugal
Estonia
Germany
Latvia


title: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase III Study to Evaluate the Efficacy and Safety of Elafibranor in Patients With Nonalcoholic Steatohepatitis (NASH) and Fibrosis

acronym: RESOLVE-IT

summary: The primary objectives of this study are to evaluate the effect of Elafibranor treatment compared to placebo on 1) histological improvement and 2) all-cause mortality and liver-related outcomes in patients with nonalcoholic steatohepatitis (NASH) and fibrosis.

status: Terminated

lead_sponsor: Genfit

location_country:
Finland
Romania
Belgium
Australia
Russian Federation
Denmark
France
Argentina
Canada
Colombia
South Africa
Chile
Sweden
Switzerland
Netherlands
Puerto Rico
Portugal
United States
Germany
United Kingdom
Italy
Mexico
Czechia
Spain
Turkey

location_facility: Rutgers, Robert Wood Johnson Medical School

location_facility: Centro De Hepatologia Ciudad de La Plata

location_facility: University Hospitals Birmingham NHS foundation Trust

location_facility: Baylor All Saints Medical Center - Baylor Research Institute

location_facility: The University of Chicago Medical Center

location_facility: Sutter West Bay Hospitals dba California Pacific Medical Center

location_facility: University of Mississippi Medical Center

location_facility: Vancouver General Hospital (VGH) - Gordon and Leslie Diamond Health Care Centre

location_facility: University of Miami - Schiff Center for Liver Diseases

location_facility: Institutul National de Boli Infectioase "Prof. Dr. Matei Bals"

location_facility: University of California, San Francisco, Fresno Community Regional Medical Center

location_facility: I. M. Sechenov - First Moscow State Medical University

location_facility: Yale University School of Medicine, Section of Digestive Diseases

location_facility: Portsmouth Hospitals NHS Trust - Queen Alexandra Hospital

location_facility: Bon Secours Liver Institute of Virginia - Newport News

location_facility: The Ohio State University Wexner Medical Center

location_facility: Istanbul Universitesi Istanbul Tip Fakultesi

location_facility: New York University Langone Medical Center

location_facility: Azienda Ospedaliera Universitaria Citta della Salute e della Scienza di Torino - Ospedale Molinette

location_facility: Florida Digestive Health Specialists, LLP

location_facility: University of Calgary, Cumming School of Medicine

location_facility: Walter Reed National Military Medical Center

location_facility: Gastrointestinal Associates & Endoscopy Center

location_facility: University of Massachusetts Memorial Medical Center

location_facility: Loma Linda University Medical Center - Transplantation Insitute

location_facility: Gastroenterology Consultants of San Antonio

location_facility: Frimley Park Hospital NHS Foundation Trust

location_facility: Nottingham University Hospitals NHS FoundationTrust - Queen's Medical Centre

location_facility: South Florida Center of Gastroenterology, PA

location_facility: M. F. Vladimirsky - Clinical Research Institution of Moscow Region

location_facility: Centro Hospitalar Lisboa Central, EPE - Hospital Santo António dos Capuchos

location_facility: University of California, San Francisco, Medical Center at Parnassus

location_facility: Hospital Universitario San Vicente de Paul Fundación

location_facility: Carolinas Center for Liver Disease, Carolinas HealthCare System/Atrium Health

location_facility: Centro Hospitalar de São João, EPE - Hospital de São João

location_facility: Saint Louis University School of Medicine

location_facility: Centro de Investigación Clínica del Pacífico, S.A de C.V.

location_facility: Centre Hospitalier de Wallonie Picardie (CHWAPI)

location_facility: Azienda Ospedaliero-Universitaria di Bologna Policlinico S. Orsola-Malpighi

location_facility: University of California, San Diego Airway Research and Clinical Trials Center

location_facility: Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico

location_facility: St George's University Hospitals NHS Foundation Trust - St George's Hospital

location_facility: Centro de Estudios Clinicos Barros Luco SPA (Patients seen, Fibroscan stored and Drug Shipment)

location_facility: Fondazione Policlinico Universitario Agostino Gemelli

location_facility: St. Luke's Liver Transplant & Specialist

location_facility: Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone

location_facility: Hospital Universitario Marqués de Valdecilla

location_facility: Digestive Health Specialists of the Southeast

location_facility: Kaiser Permanente Springfield Medical Center

location_facility: Instituto de Investigaciones Clinicas San Nicolas SRL

location_facility: Queen Elizabeth II Health Sciences Centre, Nova Scotia Health Authority

location_facility: Spitalul Clinic Judetean de Urgenta "Pius Brinzeu" Timisoara

location_facility: Centro Hospita de Tras-os-Montes e Alto Douro, EPE

location_facility: Fundacion Hospitalaria San Vicente de Paul

location_facility: Universitätsmedizin der Johannes Gutenberg-Universität Mainz

location_facility: Fundación Cardio Infantil - Instituto de Cardiología

location_facility: University at Buffalo, Clinical and Translational Research Center

location_facility: Hull and East Yorkshire Hospitals NHS Trust - Hull Royal Infirmary

location_facility: University of Louisville Medical / Dental Complex

location_facility: Bon Secours Liver Institute of Virginia - Richmond

location_facility: Campus Hospital Universitario Virgen del Rocío - Instituto de Biomedicina de Sevilla (IBIS)

location_facility: Centro Hospitalar e Universitário de Coimbra, EPE - Hospitais da Universidade de Coimbra

location_facility: Gastrointestinal Biosciences Clinical Trials LLC

location_facility: Centre Hospitalier Universitaire Vaudois (CHUV)

location_facility: Gastrointestinal Specialists of Georgia, PC

location_facility: Atlantic Gastroenterology Associates, LLC

location_facility: Sağlık Bilimleri Üniversitesi Ümraniye Eğitim ve Araştırma Hastanesi

location_facility: Centro Hospitalar de Lisboa Norte, EPE - Hospital Santa Maria

location_facility: Ospedale Casa Sollievo della Sofferenza I.R.C.C.S.

location_facility: Solano&Terront Servicios Médicos LTDA - Unidad Integral de Endocrinologia UNIENDO

location_facility: Gastroenterologie am Bayerischen Platz/ Gastro-Studien

location_facility: St Petersburg State Budgetary Healthcare Institution City Clinical Hospital N°31

location_facility: Kaiser Permanente Shady Grove Medical Center

location_facility: Medical University of South Carolina (MUSC)

location_facility: Bart Health NHS Trust- Royal London Hospital

location_facility: The Royal Free London NHS Foundation Trust - The Royal Free Hospital

location_facility: Hospital Universitario Virgen de la Victoria

location_facility: University of California, Davis Medical Center

location_facility: New York-Presbyterian Hospital - Columbia University Medical Center

location_facility: Weill Medical College of Cornell University

location_facility: Henry Ford Health System, Division of Gastroenterology & Hepatology

location_facility: Banner University Medical Center Phoenix

location_facility: Veterans Affaires Greater Los Angeles Healthcare System, West LA VA Medical Center

location_facility: SC Cabinet Particular Policlinic Algomed SRL

location_facility: Centro de Investigación y Prevención Cardiovascular SA (CIPREC)

location_facility: Veterans Affairs Greater Los Angeles Healthcare System

location_facility: University of Kentucky Chandler Medical Center

location_facility: Beth Israel Deaconess Medical Center (BIDMC)

location_facility: Universitätsklinikum Frankfurt - Goethe Universität

location_facility: University of Cincinnati Physicians Company , LLC

location_facility: Complexo Hospitalario Universitario de Pontevedra

location_facility: Inova Fairfax Medical Campus - Center for Liver Disease

location_facility: The University of Arizona College of Medicine Liver Research Institute

location_facility: Northwestern Memorial Hospital - Arkes Family Pavilion

location_facility: Marmara Üniversitesi Eğitim ve Araştırma Hastanesi

location_facility: University Hospitals Cleveland Medical Center

location_facility: The Newcastle upon Tyne Hospitals NHS Foundation Trust - Freeman Hospital

location_facility: University of Miami - Miller School of Medicine

location_facility: Plymouth Hospitals NHS Trust - Derriford Hospital

location_facility: Azienda Ospedaliera di Rilievo Nazionale "A. Cardarelli"

location_facility: Caparra Internal Medicine Research Center

location_facility: Guy's and St Thomas' NHS Foundation Trust - St Thomas' Hospital

location_facility: Swedish Organ Transplant and Liver Center

location_facility: Military medical academy n. a. S.M. Kirov

location_facility: FSBRI "Federal Research Center of nutrition and biotechnology

status_simplified: Unknown


type: Other Identifier

title: Post-Authorisation Safety Study of Esbriet® (Pirfenidone): A Prospective Observational Registry to Evaluate Long-Term Safety in a Real-World Setting

summary: This single arm, post-authorisation study is designed to evaluate the long-term safety of pirfenidone in participants with IPF. The enrolment of participants will be completed within approximately 24 months. Participants will receive pirfenidone according to the physician discretion and will be followed for 2 years. Treating physicians will collect pre-specified data at the baseline and every 3 months thereafter, for the duration of the participants' participation in study.

lead_sponsor: Hoffmann-La Roche

location_country:
Italy
Austria
Sweden
Finland
France
Norway
Ireland
Denmark
Germany
United Kingdom

location_facility: Evang. Lungenklinik Berlin Klinik für Pneumologie

location_facility: Universitätsklinikum Magdeburg Klinik für Kardiologie Angiologie u.Pneumologie

location_facility: Ospedale Morgagni-Pierantoni; U.O. Pneumologia

location_facility: Ruhrlandklinik Lungenzentrum der UNI Essen Abt.Pneumologie-Allergologie

location_facility: Johanniter-Krankenhaus im Fläming Treuenbrietzen GmbH; Fachklinik Pneumologie/ Thoraxchirurgie

location_facility: Hopital de Pontchaillou; Service de Pneumologie

location_facility: Gemeinschaftskrankenhaus Havelhöhe Klinik f.Innere Medizin Kardiologie Pneumologie

location_facility: Medical University Graz; Department for Respiratory Diseases

location_facility: RoMed Klinikum Rosenheim, Medizinische Klinik III

location_facility: Universitätsklinikum Freiburg, Abteilung Pneumologie

location_facility: Gentofte Hospital, Lungemedicinsk Afdeling

location_facility: A.O. Universitaria San Luigi Gonzaga di Orbassano; Ambulatorio per le Malattie Rare del Polmone

location_facility: Carl-Thiem-Klinik Cottbus; Medizinische Klinik

location_facility: Berufsgenossenschaftliches Uni-Klinikum Bergmannsheil GmbH

location_facility: St. Johanns-Spital; Abt. Für Lungenkrankungen

location_facility: LungenClinic Grosshansdorf GmbH; Zentrum fur Pneumologie und Thoraxchirurgie

location_facility: Haukeland Hospital - University Of Bergen: Department of Resp Med

location_facility: Universitaetsklinikum des Saarlandes; Innere Medizin V

location_facility: Southmead Hospital; Respiratory Department

location_facility: Universitätsklinikum Jena; Medizinische Klinik I

location_facility: Medizinische Universitat Innsbruck; Department of Internal Medicine, Pneumology Centre

location_facility: Hopital De La Maison Blanche;Maladies Respiratoires

location_facility: University College London Hospital; Respiratory Medicine

location_facility: Universitaetsklinikum Schleswig-Holstein, Campus Kiel

location_facility: Odense Universitetshospital, Lungemedicinsk Afdeling J

location_facility: Azienda Ospedaliero Universitaria Di Sassari; Clinica Pneumologica

location_facility: Akademiska Sjukhuset; Lungmedicinska Kliniken

location_facility: Azienda Ospedaliera Universitaria Careggi

location_facility: Helsinki University Central Hospital; Dep. of Pulmonary Medicine

location_facility: IFS - Interdisziplinäres Facharztzentrum; Institut für klinische Forschung Pneumologie

location_facility: Karolinska Universitetssjukhuset Solna; Lung Allergikliniken

location_facility: Hopital Bichat Claude Bernard ; Service de Pneumologie

location_facility: Klinikum Klagenfurt; Abteilung für Pulmologie

location_facility: Queen Alexandra Hospital; Respiratory Centre

location_facility: Universität Leipzig; Medizinische Klinik und Poliklinik I, Abteilung Pneumologie

location_facility: Royal Devon and Exeter Hospital (Wonford)

location_facility: Klinik Schillerhöhe Zentrum f.Pneumologie u.Thoraxchirurgie

location_facility: KRH Klinikum Oststadt-Heidehaus; Pneumologie, Intensiv- und Schlafmedizin

location_facility: Studienzentrum/Praxis Dr. Keller Frankfurt

location_facility: Royal Brompton Hospital; Respiratory Department

location_facility: Krankenhaus vom Roten Kreutz; Klinik fuer Pneumologie

location_facility: Klinikum Nuernberg Nord; Medizinische Klinik 3, Schwerpunkt Pneumologie, Allergologie, Schlafmedizin

location_facility: Galway University Hospital; Department of Respiratory Medicine

location_facility: Papworth Hospital NHS Foundation Trust; Respiratory Department

location_facility: A.O. Universitaria Policlinico Di Modena; DIP. Malattie Dell'apparato Respiratorio

location_facility: Southampton General Hospital; Respiratory Department

location_facility: Universitätsmedizin Greifswald Klinik für Innere Medizin B und Poliklinik

location_facility: A.O. Univ. Senese Policlinico S. Maria alle Scotte; UOC Malattie Resepiratorie e Trapianto Polmonare

location_facility: Klinikum Esslingen; Klinik für Kardiologie, Angiologie und Pneumologie

location_facility: Hopital de La Cavale Blanche; Service de Medecine Interne & de Pneumologie

location_facility: Klinikum der Universität München; Campus Großhadern; Med. Klinik und Poliklinik V

location_facility: HELIOS Klinikum Emil von Behring Klinik f.Pneumologie Onkologie u.Infektiologie

location_facility: Klinik Donaustauf Zentrum für Pneumologie

location_facility: Lungenklinik Ballenstedt/Harz gGmbH Lungenklinik Ballenstedt/Harz gGmbH

location_facility: Castle Hill Hospital; Respiratory Medicine

location_facility: Tampere University Hospital; Lung Clinic

location_facility: Universitätsklinikum Standort Gießen Medizinische Klinik II u. Poliklinik Innere Med./Pneumologie

location_facility: University Hospital of North Staffordshire; ILD Clinic

location_facility: Aarhus University Hospital; Lungemed afd. B

location_facility: Hôpital Haut-Lévêque - CHU de Bordeaux - Groupe Hospitalier Sud

location_facility: University Hospital Aintree; Pulmonary Vascular Diseases Unit

location_facility: Klinik Löwenstein gGmbH Medizinische Klinik II

location_facility: Turku University Hospital; Dept of Pulmonology

location_facility: Universitätsklinikum Würzburg, Kinderklinik u. Poliklinik

location_facility: Nottingham University Hospitals City Campus

location_facility: Lungenklinik Lostau gGmbH; Klinik für Pneumologie II

location_facility: Oslo University Hospital Rikshospitalet; Lungeavdelingen

location_facility: Universita' Degli Studi Di Milano Bicocca, Ospedale Vecchio; facolta di medicina e chirurgia, dipart

location_facility: Zentralklinik Bad Berka GmbH; Pneumologie

location_facility: Fachkrankenhaus Coswig GmbH Zentrum f.Pneumologie Beatmungsmedizin Thorax-u.Gefäßchirurgie

location_facility: Charite - Universitätsmedizin Berlin; Campus Virchow-Klinikum, Med. Klinik m. S. Infekt und Pneumo


title: Entyvio (Vedolizumab) Long-term Safety Study: An International Observational Prospective Cohort Study Comparing Vedolizumab to Other Biologic Agents in Patients With Ulcerative Colitis or Crohn's Disease

acronym: Entyvio PASS

summary: The purpose of this study is to assess the long-term safety of vedolizumab versus other biologic agents in participants with Ulcerative Colitis (UC) or Crohn's Disease (CD).

ipd_sharing_description: Takeda provides access to the de-identified individual participant data (IPD) for eligible studies to aid qualified researchers in addressing legitimate scientific objectives (Takeda's data sharing commitment is available on https://clinicaltrials.takeda.com/takedas-commitment?commitment=5). These IPDs will be provided in a secure research environment following approval of a data sharing request, and under the terms of a data sharing agreement.

lead_sponsor: Takeda

location_country:
Greece
Belgium
Denmark
Croatia
France
Norway
Canada
Slovenia
Sweden
Switzerland
Netherlands
Ireland
Portugal
United States
Germany
United Kingdom
Italy
Austria
Israel
Spain
Estonia

location_facility: Universitatsklinikum Erlangen Medizinische Klinik I - Studien Ambulanz Ced

location_facility: Nevill Hall Hospital - Aneurin Bevan Health Board

location_facility: The Royal Wolverhampton Hospitals Nhs Trust - New Cross Hospital

location_facility: St. Marien Krankenhauses - Medizinischen Klinik I

location_facility: Gastroenterologische Gemeinschaftspraxis - Stade

location_facility: Blackpool Victoria Hospital (Bvh) - Gastroenterology Department

location_facility: Hopital Rangueil - Service de Gastroenterologie

location_facility: Gastroenterologische Fachpraxis Am Germania Campus

location_facility: Technische Universitaet Dresden - Universitaetklinikum Carl Gustav Carus - Medizinische Klinik Und Poliklinik I

location_facility: St. Josef Krankenhaus Essen-Werden / Abteilung Fur Gastroenterologie

location_facility: Gastroenterology Center of Connecticut P.C.

location_facility: Boston University Moakley Building Center For Digestive Disorders

location_facility: Centre Hospitalier de Wallonie Picardie, Site Notre Dame

location_facility: General and University Hospital of Western Athens 'Attiko'

location_facility: The University of Nottingham - Nottingham Digestive Diseases Centre (Nddc) (Wolfson Digestive Diseases Centre)

location_facility: University of Iowa Hospitals and Clinics

location_facility: Medizinischen Universitat Wien - Allgemeines Krankenhaus (Akh) - Universitaetsklinik Fuer Innere Medizin Iii

location_facility: Consultants in Gastroenterology - Columbia

location_facility: University Hospital Southampton Nhs Foundation Trust

location_facility: Fondazione Irccs Ca' Granda Osp Magg Policlinico

location_facility: Universitatsklinik Und Poliklinik Fur Innere Medizin I

location_facility: Azienda Ospedaliero-Universitaria Careggi (Aouc)

location_facility: Hospices Civils de Lyon (Hcl) - Hopital Edouard Herriot

location_facility: Instituto Portugues de Oncologia de Lisboa Francisco Gentil, Epe

location_facility: Derby Hospitals Nhs Foundation Trust - Royal Derby Hospital (Derby City General Hospital)

location_facility: Nhs Foundation Trust - Homerton University Hospital (Huh)

location_facility: Universitaetsspital Bern - Inselspital - Universitaetsklinik Fuer Viszerale Chirurgie Und Medizin (Uvcm) - Klinik Und Poliklinik Fuer Gastroenterologie

location_facility: South Bay Gastroenterology Medical Group

location_facility: Hopital Du Haut Leveque - Service D'Hepato-Gastro-Enterologie Et Nutritution, Unite de Soin Normalise

location_facility: University of Sheffield - Sheffield Teaching Hospitals Nhs Foundation Trust - Royal Hallamshire Hospital (Rhh)

location_facility: Ch Valenciennes - Hopital Jean Bernard - Service Maladies de L'Appareil Digestif Et de La Nutrition

location_facility: Gemeinschaftspraxis - Endoskopiezentrum M. Hasenstein

location_facility: Fondazione Policlinico Universitario A. Gemelli

location_facility: King'S College Hospital (Kch) Nhs Foundation Trust

location_facility: Universitat Leipzig, Medizinische Fakultat

location_facility: Praxis Fur Gastroenterologie Am Bayerischen Platz

location_facility: Nyu Langone Long Island Clinical Research Associates

location_facility: Charite - Universitaetsmedizin Berlin - Campus Benjamin Franklin (Cbf) - Medizinische Klinik I

location_facility: Ordination Dr. Thomas Haas Darmpraxis Salzburg

location_facility: University Hospital of Ioannina - Division of Gastroenterology

location_facility: Universitaire Ziekenhuizen (Uz) Leuven - Gasthuisberg

location_facility: Centre Hospitalier Universitaire (Chu) de Rouen

location_facility: Assaf Harofeh Medical Center (Ahmc) - Institute of Gastroenterology

location_facility: Western Sussex Hospitals Nhs Trust - Worthing Hospital

location_facility: Centre Hospitalo Universitaire (Chu) - Hopital Saint-Antoine

location_facility: Nhs Trust - Weston Area Health - Weston General Hospital

location_facility: Hospices Civils de Lyon (Hcl) - Centre Hospitalier Lyon-Sud - Hepatogastroenterologie

location_facility: Centre Hospitalier Universitaire (Chu) de Caen - Service D'Hepatogastroenterologie

location_facility: Centre Hospitalier Regional Universitaire (Chru) de Lille - Hopital Claude Huriez

location_facility: Az Maria Middelares - Gastro-Enterologie

location_facility: Gastroenterologische Gemeinschaftspraxis Dr. Felten

location_facility: Universitaetsmedizin Mainz, I.Med.Klinik, Geb.605, Eg, Zi.0240

location_facility: Service Gastro-Enterologie Hopital Nord - Chu de Saint Etienne

location_facility: Chu Hopital Nord, Marseille - Service D'Hepato-Gastro-Enterologie

location_facility: General Hospital of Athens 'Evangelismos'

location_facility: Universitatsklinikum Magdeburg A. O. R. - Klinik Fur Gastroenterologie

location_facility: Illinois Gastroenterology Groupllc Northwest Gastroenterologists

location_facility: The Shrewsbury and Telford Hospital Nhs Trust - Royal Shrewsbury Hospital

location_facility: Az Groeninge - Campus Kennedylaan - Gastro-Enterologie

location_facility: Complexo H. Pontevedra-Hospital de Montecelo

location_facility: Chu de Clermont Ferrand - Hopital Estaing

location_facility: Middlesex Gastroenterology Associates, Llc

location_facility: Oslo Univeristy Hospital Ulleval Hospital

location_facility: Ziekenhuis Oost Limburg - Gastro-Enterologie

location_facility: University Hospitals Coventry and Warwickshire Nhs Trust - University Hospital (Walsgrave Hospital)

location_facility: Medizinisches Versorgungszentrum (Mvz) Dachau

location_facility: Krankenhaus Martha-Maria Halle Dolau Ggmbii, Klinik Fur Innere Medizin I

location_facility: Wake Forest University School of Medicine

location_facility: Ospedale Morgagni Pierantoni Forli U.O. Gastroenterologia Ed Endoscopia

location_facility: Universita Di Salerno Aou San Giovanni Di Dio E Ruggi D'Aragona

location_facility: Emory University Hospital, the Emory Clinic

location_facility: Kantonsspital St. Gallen - Gastroenterologie

location_facility: Spedali Civili Gastroenterology Unit University of Brescia

location_facility: Centre Hospitalier Universitaire (Chu) de Nice - Hopital L'Archet 2 - Pole Digestif

location_facility: St. Panteleimon General Hospital of Nikaia

location_facility: University of Toronto - St. Michaels Hospital

location_facility: Chu Saint Pierre - Service de Gastroenterologie

location_facility: University and General Hospital of Alexandroupoli

location_facility: A.O. Guido Salvini Di Garbagnate Milanese

location_facility: University and General Hospital of Heraklion

location_facility: Charite Campus Virchow Klinikum - Medizinische Klinik Mit Schwerpunkt Hepatologie Und Gastroenterologie

location_facility: Universitaetsklinikum Mannheim (Umm) - Ii Medizinische Klinik

location_facility: The North West London Hospitals Nhs Trust (Nwlh) - St Mark'S Hospital

location_facility: Azienda Ospedaliera Per Lemergenza Cannizzaro

location_facility: Pinderfields Hospital - Mid Yorkshire Hospital Trust

location_facility: Rambam Health Care Campus (Rhcc) - Institute of Gastroenterology

location_facility: Chu Amiens Picardie - Service Hepato-Gastro-Enterologie

location_facility: Agaplesion Markus Krankenhaus, Medizinische Klinik 1

location_facility: Medizinische Versorgungszentrum Portal 10

location_facility: Centre Hospitalier Chretien (Chc) - Clinique Saint-Joseph (Hopital St-Joseph) - Gastro-Enterologie

location_facility: Gastroenterologische Praxis Balsiger, Seibold & Partner Crohn-Colitis-Zentrum Hochhaus Lindenhofspital

location_facility: Tel Aviv University - Rabin Medical Center - Beilinson Hospital


title: On Demand vs Continuous Treatment of Endoscopy Negative Subjects With Gastroesophageal Reflux Disease (GERD) With Esomeprazole 20-mg Once Daily Over a 6 Months Long Term Treatment Phase. An Open, Randomised, Multicenter Study. NEED.

acronym: NEED

summary: The purpose of this study is to compare on demand with continuous treatment of endoscopy negative subjects with gastroesophageal reflux disease (GERD), with esomeprazole 20-mg once daily, with regards to willingness to continue in the study as a result of satisfactory treatment over a six-month long term management period, after initial symptom relief.

ReferenceCitation: Bayerdörffer E, Bigard MA, Weiss W, Mearin F, Rodrigo L, Dominguez Muñoz JE, Grundling H, Persson T, Svedberg LE, Keeling N, Eklund S. Randomized, multicenter study: on-demand versus continuous maintenance treatment with esomeprazole in patients with non-erosive gastroesophageal reflux disease. BMC Gastroenterol. 2016 Apr 14;16:48. doi: 10.1186/s12876-016-0448-x.

family: Bayerdörffer

full_name: Ekkehard Bayerdörffer

given: Ekkehard

family: Bigard

full_name: Marc-Andre Bigard

given: Marc-Andre

family: Weiss

full_name: Werner Weiss

given: Werner

family: Mearin

full_name: Fermín Mearin

given: Fermín

family: Rodrigo

full_name: Luis Rodrigo

given: Luis

family: Dominguez Muñoz

full_name: Juan Enrique Dominguez Muñoz

given: Juan Enrique

family: Grundling

full_name: Hennie Grundling

given: Hennie

family: Persson

full_name: Tore Persson

given: Tore

family: Svedberg

full_name: Lars-Erik Svedberg

given: Lars-Erik

family: Keeling

full_name: Nanna Keeling

given: Nanna

family: Eklund

full_name: Stefan Eklund

given: Stefan

currency_apc_doaj: GBP

journal_name: BMC Gastroenterology

oa_colors: green gold

evidence: oa journal (via doaj)

license: cc-by

license_normalized: cc-by

host_type: repository

repository_institution: PubMed Central - Europe PMC

repository_normalized: PubMed Central

evidence: oa repository (via pmcid lookup)

publisher: Springer Science and Business Media LLC

publisher_dissemination: Springer-Nature

publisher_group: Springer-Nature

publisher_normalized: Springer

lead_sponsor: AstraZeneca

location_country:
Austria
South Africa
France
Spain
Germany

location_facility: Gastroenterology Clinic, Parorama Medi-Clinic

location_facility: Gastroenterology Unit, Room C78, Tygerberg Hospital

location_facility: Gastroenterology Clinic, Milpark Hospital

location_facility: Gastroenterology Clinic, G73, Department of Internal Medicine, Universitas Hospital

location_facility: Gastroenterology Clinic, Parklands Medical Centre

location_facility: Gastroenterology Unit, Chris Hani Baragwanath Hospital

location_facility: Carl Gustav Carus der Tecnischen Universität

location_facility: Gastroenterology Clinic, E23, Groote Schuur Hospital Observatory


title: Factor XA - Inhibition in RENal Patients With Non-valvular Atrial Fibrillation - Observational Registry

acronym: XARENO

summary:
The multicenter registry will collect clinical data from 1600 patients with non valvular atrial fibrillation (NVAF) and chronic kidney disease (eGFR 15-49 mL/min per 1.73 m2).

The overall objective of this registry is to assess chronic kidney disease (CKD) progression and clinical outcomes with regard to anticoagulation strategies in NVAF patients with eGFR 15-49 mL/min per 1.73 m2 in routine clinical practice.

lead_sponsor: GWT-TUD GmbH

location_country: Austria Switzerland France Belgium Germany

location_facility: Studienzentrum Dr. med. Karl-Friedrich Appel

location_facility: Praxis Dr. med. Christoph Axthelm & Kollegen

location_facility: Zentrum für Nieren-, Hochdruck und Stoffwechselerkrankungen

location_facility: Centre Hospitalier de Wallonie Picarde (Chwapi)

location_facility: CH Argenteuil Centre Hospitalier Victor Dupouy

location_facility: Centre Hospitalier Universiatire du SART-TILMAN

location_facility: St. Joseph Krankenhaus Berlin-Tempelhof GmbH

location_facility: Centre Hospitalier Régional de la Citadelle

location_facility: Universitätsmedizin der Johannes Gutenberg-Universität Mainz

location_facility: Gemeinschaftspraxis Scheuermann & Persicke

location_facility: Zentrum für Prävention und Rehabilitation

location_facility: Marienkrankenhaus Klinikum St. Elisabeth

location_facility: Schilddrüsenzentrum Bergstrasse/Praxis Innere Medizin

location_facility: CHI Toulon La Seyne sur mer - Hopital Sainte Musse

location_facility: CHG de Chartres-Hôpital Général Louis Pasteur

location_facility: Centre Hospitalier Chrétien (CHC) St Joseph

location_facility: Krankenhaus Hietzing mit Neurologischem Zentrum Rosenhügel

location_facility: Gemeinschaftspraxis Kellner und Ehrhardt

location_facility: Gemeinschaftspraxis Wittwer, Bargemann, Baar

location_facility: Kardiologische Praxis Dr. med. Ayham Al Zoebi

location_facility: Universitätsklinikum Carl Gustav Carus Dresden

location_facility: Gemeinschaftspraxis im Altstadtcarree, Kardiologie

location_facility: Gemeinschaftspraxis Dr. med. Sybille Jänsch


title: A Randomized Parallel Group Phase III Trial of OSE2101 as 2nd or 3rd Line Compared With Standard Treatment (Docetaxel or Pemetrexed) in HLA-A2 Positive Patients With Advanced Non-Small-Cell Lung Cancer With Progressive Disease After Last Treatment With Immune Checkpoint Inhibitors (ICI). (OSE2101C301)

acronym: ATALANTE 1

summary: The aim of this study is to determine if the Investigational Medicinal Product Tedopi (OSE2101) is more effective than standard treatment in treating patients with stage IIIB NSCLC unsuitable for radiotherapy or metastatic NSCLC in second- or third-line treatment after failure of immune checkpoint-inhibitor regimens.

ReferenceType: background

ReferenceCitation: Barve M, Bender J, Senzer N, Cunningham C, Greco FA, McCune D, Steis R, Khong H, Richards D, Stephenson J, Ganesa P, Nemunaitis J, Ishioka G, Pappen B, Nemunaitis M, Morse M, Mills B, Maples PB, Sherman J, Nemunaitis JJ. Induction of immune responses and clinical efficacy in a phase II trial of IDM-2101, a 10-epitope cytotoxic T-lymphocyte vaccine, in metastatic non-small-cell lung cancer. J Clin Oncol. 2008 Sep 20;26(27):4418-25. doi: 10.1200/JCO.2008.16.6462.

ReferenceCitation: Beebe M, Qin M, Moi M, Wu S, Heiati H, Walker L, Newman M, Fikes J, Ishioka GY. Formulation and characterization of a ten-peptide single-vial vaccine, EP-2101, designed to induce cytotoxic T-lymphocyte responses for cancer immunotherapy. Hum Vaccin. 2008 May-Jun;4(3):210-8. Epub 2010 May 11.

ReferenceCitation: Nemunaitis J, Cunningham, C ,Bender, J, Ishioka, G, Maples, P, Pappen, B, Stephenson, J, Morse, M, Mills, B, Greco, A, McCune, D, Steis, R, Nugent, F, Khong, HT, Richards, D. Phase II trial of a 10-epitope CTL vaccine, IDM-2101, in metastatic NSCLC patients: Induction of immune responses and clinical efficacy. International Society for Biological Therapy of Cancer 2007, p 891-2.

lead_sponsor: OSE Immunotherapeutics

location_country:
Italy
United States
France
Czechia
Poland
Israel
Hungary
Spain
Germany
United Kingdom

location_facility: UOC di Oncologia Medica Policlinico Universitario Campus Biomedico

location_facility: Hospital Universitario La Paz Servicio de Oncología Médica

location_facility: Azienda USL 2 Lucca - Dipartimento Oncologico

location_facility: Hospital Universitario Germans Trias i Pujol

location_facility: Centre Hospitalier Régional Universitaire de Tours

location_facility: Országos Korányi TBC és Pulmonológiai Intézet XIV Tüdőbelosztály

location_facility: Krankenhaus Mehrheit - Kliniken der Stadt Köln - Lungenklinik

location_facility: Unità Operativa di Oncologia dell'Ospedale Vito Fazzi di Lecce, Piazza Muratore

location_facility: Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (I.R.S.T)

location_facility: Csongrad Megyei Mellkasi Betegsegek Szakkorháza I Tüdőosztály

location_facility: Wojewódzki Szpital Zespolony , Oddział Chemioterapii Nowotworów

location_facility: Universitätsklinikum Tübingen Medizinische Klinik II

location_facility: "Complejo Hospitalario Universitario A Coruna (CHUAC)"

location_facility: Országos Korányi TBC és Pulmonológiai Intézet XI Tüdőbelosztály

location_facility: Klinik für Innere Medizin II Hospital Martha-Maria Halle-Dölau gGmbH

location_facility: East Valley Hematology and Oncology medical Group

location_facility: Magyar Honvedseg Egeszsegugyi Kozpont II szamu telephely

location_facility: UOC di Oncologia Medica, Policlinico Universitario Campus Biomedico

location_facility: U.O.C. Pneumologia a indirizzo oncologico, Presidio Ospedaliero Monaldi - Azienda Ospedaliera dei Colli - Via Leonardo Bianchi

location_facility: U.O Oncologia ed Ematologia, Ospedale Santa Maria delle Croci

location_facility: Klinik für Innere Medizin II Universitätsklinikum Ulm

location_facility: Mazowieckie Centrum Leczenia chorób Płuc i Gruźlicy

location_facility: Klinika Onkologii i Radioterapii , Uniwersyteckie Centrum Kliniczne

location_facility: Semmelweis Egyetem Altalanos Orvostudományi Kar Pulmonologiai Klinika

location_facility: Hospital Universitario Puerta de Hierro Majadahonda Servicio de Oncología Médica Consultas externas, 2ª planta


publications_result: Jacobson IM, Asselah T, Nahass R, Bhandari BR, Tran A, Hyland RH, et al. A Randomized Phase 3 Trial of Sofosbuvir/Velpatasvir/Voxilaprevir for 8 Weeks Compared to Sofosbuvir/Velpatasvir for 12 Weeks in DAA-Naïve Genotype 1-6 HCV-Infected Patients: The POLARIS-2 Study [Abstract LB-12]. Hepatology AASLD Abstracts 2016;64 (6 (suppl)):1126A.

ReferenceType: result

ReferenceCitation: Jacobson IM, Lawitz E, Gane EJ, Willems BE, Ruane PJ, Nahass RG, Borgia SM, Shafran SD, Workowski KA, Pearlman B, Hyland RH, Stamm LM, Svarovskaia E, Dvory-Sobol H, Zhu Y, Subramanian GM, Brainard DM, McHutchison JG, Bräu N, Berg T, Agarwal K, Bhandari BR, Davis M, Feld JJ, Dore GJ, Stedman CAM, Thompson AJ, Asselah T, Roberts SK, Foster GR. Efficacy of 8 Weeks of Sofosbuvir, Velpatasvir, and Voxilaprevir in Patients With Chronic HCV Infection: 2 Phase 3 Randomized Trials. Gastroenterology. 2017 Jul;153(1):113-122. doi: 10.1053/j.gastro.2017.03.047. Epub 2017 Apr 5.

family: Jacobson

full_name: Ira M. Jacobson

given: Ira M.

family: Lawitz

full_name: Eric Lawitz

given: Eric

family: Gane

full_name: Edward J. Gane

given: Edward J.

family: Willems

full_name: Bernard E. Willems

given: Bernard E.

family: Ruane

full_name: Peter J. Ruane

given: Peter J.

family: Nahass

full_name: Ronald G. Nahass

given: Ronald G.

family: Borgia

full_name: Sergio M. Borgia

given: Sergio M.

family: Shafran

full_name: Stephen D. Shafran

given: Stephen D.

family: Workowski

full_name: Kimberly A. Workowski

given: Kimberly A.

family: Pearlman

full_name: Brian Pearlman

given: Brian

family: Hyland

full_name: Robert H. Hyland

given: Robert H.

family: Stamm

full_name: Luisa M. Stamm

given: Luisa M.

family: Svarovskaia

full_name: Evguenia Svarovskaia

given: Evguenia

family: Dvory-Sobol

full_name: Hadas Dvory-Sobol

given: Hadas

family: Zhu

full_name: Yanni Zhu

given: Yanni

family: Subramanian

full_name: G. Mani Subramanian

given: G. Mani

family: Brainard

full_name: Diana M. Brainard

given: Diana M.

family: McHutchison

full_name: John G. McHutchison

given: John G.

family: Bräu

full_name: Norbert Bräu

given: Norbert

family: Berg

full_name: Thomas Berg

given: Thomas

family: Agarwal

full_name: Kosh Agarwal

given: Kosh

family: Bhandari

full_name: Bal Raj Bhandari

given: Bal Raj

family: Davis

full_name: Mitchell Davis

given: Mitchell

family: Feld

full_name: Jordan J. Feld

given: Jordan J.

family: Dore

full_name: Gregory J. Dore

repository_institution: Queen Mary University of London - Queen Mary Research Online

ipd_sharing_description: Qualified external researchers may request IPD for this study after study completion. For more information, please visit our website at https://www.gilead.com/about/ethics-and-code-of-conduct/policies.

location_country:
United States
Germany
France
Australia
Puerto Rico
New Zealand
Canada
United Kingdom

title: A Phase 3, Global, Multicenter, Randomized, Open-Label Study to Investigate the Safety and Efficacy of Sofosbuvir/Velpatasvir/GS-9857 Fixed-Dose Combination for 8 Weeks Compared to Sofosbuvir/Velpatasvir for 12 Weeks in Direct-Acting Antiviral-Naïve Subjects With Chronic HCV Infection

summary: The primary objectives of this study are to compare the efficacy, safety, and tolerability of treatment with sofosbuvir/velpatasvir/voxilaprevir (SOF/VEL/VOX) fixed dose combination (FDC) for 8 weeks with that of SOF/VEL FDC for 12 weeks in direct-acting antiviral-naive participants with chronic hepatitis C virus (HCV) infection.


ReferenceCitation: Bourlière M, Gordon SC, Ramji A, Ravendhran N, Tran TT, Hyland RH, et al. Sofosbuvir/Velpatasvir/Voxilaprevir for 12 Weeks as a Salvage Regimen in NS5A Inhibitor-Experienced Patients with Genotype 1-6 Infection: The Phase 3 POLARIS-1 Study [Abstract 194]. J Hepatology 2016;63 (1S):102A.

ReferenceCitation: Younossi ZM, Stepanova M, Gordon S, Zeuzem S, Mann MP, Jacobson I, Bourliere M, Cooper C, Flamm S, Reddy KR, Kowdley K, Younossi I, Hunt S. Patient-Reported Outcomes Following Treatment of Chronic Hepatitis C Virus Infection With Sofosbuvir and Velpatasvir, With or Without Voxilaprevir. Clin Gastroenterol Hepatol. 2018 Apr;16(4):567-574.e6. doi: 10.1016/j.cgh.2017.11.023. Epub 2017 Nov 16.

ReferenceCitation: Bourlière M, Gordon SC, Schiff ER, Tran TT, Ravendhran N, Landis CS, Hyland RH, Stamm LM, Zhang J, Dvory-Sobol H, Subramanian GM, Brainard DM, McHutchison JG, Serfaty L, Thompson AJ, Sepe TE, Curry MP, Reddy KR, Manns MP. Deferred treatment with sofosbuvir-velpatasvir-voxilaprevir for patients with chronic hepatitis C virus who were previously treated with an NS5A inhibitor: an open-label substudy of POLARIS-1. Lancet Gastroenterol Hepatol. 2018 Aug;3(8):559-565. doi: 10.1016/S2468-1253(18)30118-3. Epub 2018 May 31.

ReferenceCitation: Bourlière M, Gordon SC, Flamm SL, Cooper CL, Ramji A, Tong M, Ravendhran N, Vierling JM, Tran TT, Pianko S, Bansal MB, de Lédinghen V, Hyland RH, Stamm LM, Dvory-Sobol H, Svarovskaia E, Zhang J, Huang KC, Subramanian GM, Brainard DM, McHutchison JG, Verna EC, Buggisch P, Landis CS, Younes ZH, Curry MP, Strasser SI, Schiff ER, Reddy KR, Manns MP, Kowdley KV, Zeuzem S; POLARIS-1 and POLARIS-4 Investigators. Sofosbuvir, Velpatasvir, and Voxilaprevir for Previously Treated HCV Infection. N Engl J Med. 2017 Jun 1;376(22):2134-2146. doi: 10.1056/NEJMoa1613512.

family: Bourlière

full_name: Marc Bourlière

given: Marc

family: Gordon

full_name: Stuart C. Gordon

given: Stuart C.

family: Flamm

full_name: Steven L. Flamm

given: Steven L.

family: Cooper

full_name: Curtis L. Cooper

given: Curtis L.

family: Ramji

full_name: Alnoor Ramji

given: Alnoor

family: Tong

full_name: Myron Tong

given: Myron

family: Ravendhran

full_name: Natarajan Ravendhran

given: Natarajan

family: Vierling

full_name: John M. Vierling

given: John M.

family: Tran

full_name: Tram T. Tran

given: Tram T.

family: Pianko

full_name: Stephen Pianko

given: Stephen

family: Bansal

full_name: Meena B. Bansal

given: Meena B.

family: de Lédinghen

full_name: Victor de Lédinghen

given: Victor

family: Zhang

full_name: Jie Zhang

given: Jie

family: Huang

full_name: K.C. Huang

family: Verna

full_name: Elizabeth C. Verna

given: Elizabeth C.

family: Buggisch

full_name: Peter Buggisch

given: Peter

family: Landis

full_name: Charles S. Landis

given: Charles S.

family: Younes

title: A Phase 3, Global, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Safety and Efficacy of Sofosbuvir/Velpatasvir/GS-9857 Fixed-Dose Combination for 12 Weeks in Direct-Acting Antiviral-Experienced Subjects With Chronic HCV Infection

summary:
The primary objectives of this study are to evaluate the safety and efficacy of treatment with sofosbuvir/velpatasvir/voxilaprevir (SOF/VEL/VOX) in adults with chronic hepatitis C virus (HCV) infection who have previously received treatment with direct-acting antiviral therapy.

Participants randomized to placebo may be eligible for deferred treatment with active SOF/VEL/VOX.


ReferenceCitation: Powles T, Park SH, Voog E, Caserta C, Valderrama BP, Gurney H, Kalofonos H, Radulović S, Demey W, Ullén A, Loriot Y, Sridhar SS, Tsuchiya N, Kopyltsov E, Sternberg CN, Bellmunt J, Aragon-Ching JB, Petrylak DP, Laliberte R, Wang J, Huang B, Davis C, Fowst C, Costa N, Blake-Haskins JA, di Pietro A, Grivas P. Avelumab Maintenance Therapy for Advanced or Metastatic Urothelial Carcinoma. N Engl J Med. 2020 Sep 24;383(13):1218-1230. doi: 10.1056/NEJMoa2002788. Epub 2020 Sep 18.

name: From Barts Cancer Institute, Experimental Cancer Medicine Centre, Queen Mary University of London, St. Bartholomew’s Hospital, London (T.P.); Sungkyunkwan University Samsung Medical Center, Seoul, South Korea (S.H.P.); Centre Jean Bernard Clinique Victor Hugo, Le Mans (E.V.), and Gustave Roussy, INSERM Unité 981, Université Paris-Saclay, Villejuif (Y.L.) — both in France; the Medical Oncology Unit, Azienda Ospedaliera S. Maria, Terni (C.C.), and Pfizer, Milan (C.F., A.P.) — both in Italy; the Department...

family: Powles

full_name: Thomas Powles

given: Thomas

family: Park

full_name: Se Hoon Park

given: Se Hoon

family: Voog

full_name: Eric Voog

given: Eric

family: Caserta

full_name: Claudia Caserta

given: Claudia

family: Valderrama

full_name: Begoña P. Valderrama

given: Begoña P.

family: Gurney

full_name: Howard Gurney

given: Howard

family: Kalofonos

full_name: Haralabos Kalofonos

given: Haralabos

family: Radulović

full_name: Siniša Radulović

given: Siniša

family: Demey

full_name: Wim Demey

given: Wim

family: Ullén

full_name: Anders Ullén

given: Anders

family: Loriot

full_name: Yohann Loriot

given: Yohann

family: Sridhar

full_name: Srikala S. Sridhar

given: Srikala S.

family: Tsuchiya

full_name: Norihiko Tsuchiya

given: Norihiko

family: Kopyltsov

full_name: Evgeny Kopyltsov

given: Evgeny

family: Sternberg

full_name: Cora N. Sternberg

given: Cora N.

family: Bellmunt

full_name: Joaquim Bellmunt

given: Joaquim

family: Aragon-Ching

full_name: Jeanny B. Aragon-Ching

given: Jeanny B.

family: Petrylak

full_name: Daniel P. Petrylak

given: Daniel P.

family: Laliberte

full_name: Robert Laliberte

given: Robert

family: Wang

full_name: Jing Wang

given: Jing

full_name: Bo Huang

given: Bo

family: Davis

full_name: Craig Davis

given: Craig

family: Fowst

full_name: Camilla Fowst

given: Camilla

family: Costa

full_name: Nuno Costa

given: Nuno

family: Blake-Haskins

full_name: John A. Blake-Haskins

given: John A.

ipd_sharing_description: Pfizer will provide access to individual de-identified participant data and related study documents (e.g. protocol, Statistical Analysis Plan (SAP), Clinical Study Report (CSR)) upon request from qualified researchers, and subject to certain criteria, conditions, and exceptions. Further details on Pfizer's data sharing criteria and process for requesting access can be found at: https://www.pfizer.com/science/clinical_trials/trial_data_and_results/data_requests.

location_country:
Greece
Belgium
Australia
Russian Federation
Denmark
Taiwan
India
France
Japan
Poland
Norway
Argentina
Canada
Korea, Republic of
Sweden
Hong Kong
Netherlands
Hungary
Portugal
United States
United Kingdom
Italy
Brazil
Serbia
Mexico
Czechia
Israel
New Zealand
Spain

location_facility: Anschutz Cancer Center Pavilion Pharmacy

location_facility: Uniao Brasileira de Educacao e Assistencia / Hospital Sao Lucas da PUCRS

location_facility: University of Colorado Hospital - Anschutz Inpatient Pavilion (AIP)

location_facility: Severance Hospital Yonsei University Health System

location_facility: Churchill Hospital, Oxford University Hospitals NHS Trust

location_facility: CENOB Centro de Oncologia da Bahia S/S Ltda. / Oncovida

location_facility: Hospital Clinico Universitario de Valencia

location_facility: Centro de Investigación Clínica de Leon S.C.

location_facility: Smilow Cancer Hospital at Yale New Haven

location_facility: CHUM - Centre Hospitalier de l'Universite de Montreal

location_facility: Hospital Regional Dr. Enrique Vera Barros

location_facility: Centro Integrado de Pesquisa Clinica - CIP

location_facility: National Cancer Center - Clinical Trial Pharmacy

location_facility: Centro Oncologico Riojano Integral (Cori)

location_facility: Department of Pharmacy, National Cheng Kung University Hospital

location_facility: Klinik for Klinisk Fysiologi,Nuklearmedicin og PET

location_facility: Non-State Healthcare Institution "Railway Clinical Hospital JSC RZhD"

location_facility: Centre de Radiothérapie - Clinique Sainte Anne

location_facility: Institut de cancérologie de l'Ouest - Site Paul Papin

location_facility: Hamamatsu University School of Medicine, University Hospital

location_facility: Dr Ram Manohar Lohia (RML) Hospital & PGI MER

location_facility: Samsung Medical Center Clinical Trial Pharmacy

location_facility: Fundación CENIT para la Investigación en Neurociencias

location_facility: National Hospital Organization hokkaido Cancer Center

location_facility: Associação Educadora São Carlos - AESC / Hospital Mãe de Deus - Farmácia Oncológica

location_facility: Rigshospitalet, Onkologisk Klinik, afsnit 5073

location_facility: Kobe City Medical Center General Hospital

location_facility: Royal United Hospitals Bath NHS Foundation Trust

location_facility: Rajiv Gandhi Cancer Institute and Research Centre

location_facility: Associação Educadora São Carlos - AESC / Hospital Mãe de Deus - Centro de Abastecimento Farmaceu

location_facility: Azienda Ospedaliera di Rilievo Nazionale "A. Cardarelli"

location_facility: University General Hospital of Patras, Division of Oncology

location_facility: Chemotherapy pharmacy, Chang Gung Memorial Hospital, Linkou

location_facility: Hospital Universitario Germans Trias i Pujol

location_facility: Icon Cancer Care SA trading as Icon Pharmacy Adelaide

location_facility: Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori

location_facility: Fundacao Faculdade Regional de Medicina de Sao Jose do Rio Preto

location_facility: Institute for Oncology and Radiology of Serbia

location_facility: Private Medical Institution "Evromedservice"

location_facility: FSBEI HE "First St. Petersburg State Medical University n.a. academician I.P Pavlov" MoH RF

location_facility: CIMS Cancer, Care Institute of Medical Sciences, CIMS Hospital

location_facility: Institut de Cancérologie de l'Ouest - Centre René Gauducheau

location_facility: Hospital Comarcal General de Elda de Virgen de la Salud

location_facility: SHI YR "Regional Clinical Oncology Hospital"

location_facility: Hospital de La Santa Creu i Sant pau_Oncology department

location_facility: C. H. Universitario de Vigo- Hospital Álvaro Cunqueiro

location_facility: Associação Educadora São Carlos - AESC / Hospital Mãe de Deus - Ambulatório Quimioterapia

location_facility: Chungnam National University Hospital, Clinical Pharmacy

location_facility: Smilow Cancer Hospital at Yale-New Haven

location_facility: Wojewodzki Szpital Zespolony im. L. Rydygiera w Toruniu Szpital Obserwacyjno-Zakazny

location_facility: Istituto Nazionale per lo Studio e la Cura dei Tumori, IRCCS Fondazione Giovanni Pascale

location_facility: National Hospital Organization Shikoku Cancer Center

location_facility: Phylasis Clinicas Research S. de R.L. de C.V.

location_facility: Moscow Research Oncology Institute named after P. A. Gertsen

location_facility: State Budgetary Healthcare Insti. Republican Clinical Oncology Dispensary of the MoH of Bashk. Rep.

location_facility: Hospital Universitario HM Sanchinarro - CIOCC

location_facility: Hospital Médica Campestre (Administradora Hospitalaria S.A de C.V.)

location_facility: Institut Catalá d'Oncología - Hospital Duran i Reynals

location_facility: Centre d'Oncologie et de Radiothérapie du Pays-Basque

location_facility: Principal Military Clinical Hospital n.a. N.N. Burdenko

location_facility: University of Colorado Denver, CTO (CTRC)

location_facility: Azienda Ospedaliero-Universitaria Policlinico S.Orsola Malpighi

location_facility: AUSL della Romagna - RAVENNA, Presidio Ospedaliero di Faenza

location_facility: FSBEI HE "First St. Petersburg State Medical University n. a. academician l.P Pavlov" MoH RF

location_facility: Clinical Trial Pharmacy, China Medical University Hospital

location_facility: Alexandra General Hospital, Oncology Department

location_facility: Federal State Budgetary Institution "National medical research radiology center" MoH RF

location_facility: Koo Foundation Sun Yat-Sen Cancer Center

location_facility: Hospital Clínico Universitario de Valencia

location_facility: National Hospital Organization Kyushu Cancer Center

location_facility: National Hospital Organization Sagamihara National Hospital

location_facility: FGBIH "Clinical Hospital #122 n.a. L.G. Sokolov of Federal Medico-biological agency"

location_facility: EUROMEDICA General Clinic of Thessaloniki

location_facility: FSBI "Russian Scientific Center For Radiology and Surgical Technologies n.a. Academician A.M. Granov

location_facility: Hospital das Clinicas da Faculdade de Medicina da USP - HCFMUSP

location_facility: C.H. Universitario de Vigo- Hospital Meixoeiro

location_facility: Hospital General Universitario Gregorio Marañon

location_facility: Instituto Português de Oncologia do Porto Francisco Gentil, EPE

location_facility: Servizio Farmacia Ospedaliera - Farmacia Oncologica

location_facility: Inova Schar Cancer Institute Infusion Pharmacy

location_facility: Fondazione IRCCS Istituto Nazionale Dei Tumori

location_facility: Saitama Medical University International Medical Center

location_facility: Instituto Português de Oncologia de Coimbra Francisco Gentil, EPE

location_facility: Centro Hospitalar de Trás-os-Montes e Alto Douro, EPE

location_facility: Centrum Onkologii Ziemi Lubelskiej im. Sw. Jana z Dukli

location_facility: Seoul National University Bundang Hospital

location_facility: Hiroshima City Hiroshima Citizens Hospital

location_facility: Ballarat Oncology & Haematology Services

location_facility: National Cancer Center Urology center for Prostate Cancer

location_facility: Sociedade Beneficente de Senhoras Hospital Sírio Libanês/ Instituo Sirio Libanes de Ensino e Pesqu

location_facility: Centro Hospitalar de Lisboa Central, E.P.E. - Hospital de Santo António dos Capuchos

location_facility: Hirosaki University School of Medicine & Hospital

location_facility: Hôpital Privé Toulon-Hyères - Clinique Sainte Marguerite

location_facility: Seoul National University Bundang Hospital, Clinical Pharmacy

location_facility: Dokkyo Medical University Saitama Medical Center

location_facility: Associação Hospital de Caridade Ijuí / Hospital de Caridade de Ijuí

location_facility: Guy's and St Thomas' NHS Foundation Trust, Guy's Hospital

location_facility: Fundacao Faculdade de Medicina / Instituto do Cancer do Estado de Sao Paulo - ICESP

location_facility: Asan Medical Center - Clinical Trial Pharmacy

location_facility: CHU Nimes - Institut de Cancerologie du Gard

location_facility: St Bartholomew 's Hospital, Barts Health NHS Trust

location_facility: St. Bartholomew's Hospital, Barts Health NHS Trust

location_facility: Hospital Universitario Central de Asturias

location_facility: BHI of Omsk region "Clinical oncological dispensary"

location_facility: Guy's & St. Thomas' NHS Foundation Trust

location_facility: Azienda Ospedaliera San Camillo Forlanini_Oncologia Medica

location_facility: Althaia. Xarxa Assistencial Universitaria de Manresa

location_facility: National Hospital Organization Kumamoto Medical Center

location_facility: Niigata University Medical & Dental Hospital

location_facility: Wojewodzki Szpital Zespolony im. L. Rydygiera w Toruniu

location_facility: Wojewodzki Szpital Zespolony im. L. Rydygiera, Szpital Specjalistyczny dla Dzieci I Doroslych

location_facility: Dr. Campos Costa - Consultório de Tomografia Computorizada, S.A.- Matosinhos

location_facility: University of Colorado Hospital - Anschutz Outpatient Pavilion (AOP)

location_facility: Centro di Riferimento Oncologico - IRCCS

location_facility: Fondazione del Piemonte per l'Oncologia - IRCCS Candiolo

location_facility: Investigational Drug services, National Taiwan University Hospital

location_facility: Fundacion Maria Rafols para la investigacion del Diagnostico de la imagen

title: A PHASE 3, MULTICENTER, MULTINATIONAL, RANDOMIZED, OPEN-LABEL, PARALLEL-ARM STUDY OF AVELUMAB (MSB0010718C) PLUS BEST SUPPORTIVE CARE VERSUS BEST SUPPORTIVE CARE ALONE AS A MAINTENANCE TREATMENT IN PATIENTS WITH LOCALLY ADVANCED OR METASTATIC UROTHELIAL CANCER WHOSE DISEASE DID NOT PROGRESS AFTER COMPLETION OF FIRST-LINE PLATINUM-CONTAINING CHEMOTHERAPY

summary: The main purpose of this study is to compare maintenance treatment with avelumab plus best supportive care (BSC) with BSC alone, to determine if avelumab has an effect on survival in patients with locally advanced or metastatic urothelial cancer that did not worsen during or following completion of first-line chemotherapy.


title: Clinical Trial of Nivolumab (BMS-936558) Combined With Ipilimumab Followed by Nivolumab Monotherapy as First-Line Therapy of Subjects With Histologically Confirmed Stage III (Unresectable) or Stage IV Melanoma CheckMate 401: CHECKpoint Pathway and nivoluMAb Clinical Trial Evaluation 401

acronym: CheckMate 401

summary: The purpose of this study is to determine the effects of combination treatment of Nivolumab with Ipilimumab followed by Nivolumab monotherapy in patients with previously untreated advanced Melanoma.

design_allocation: Non-Randomized

lead_sponsor: Bristol-Myers Squibb

location_country:
Italy
Austria
Sweden
Switzerland
Finland
France
Norway
Ireland
Australia
Belgium
Germany
United Kingdom

location_facility:
Mount Vernon Hospital
Local Institution


title: A Phase 3, Randomized, Double-blind, Placebo-controlled, Multicenter Study to Investigate the Efficacy and Safety of Mongersen (GED-0301) for the Treatment of Subjects With Active Crohn's Disease

summary:
The purpose of study is to test the effects of an experimental medication GED-0301 (mongersen) in patients who have active Crohn's disease. The study will test GED-0301 compared to placebo for 52 weeks. The study treatment is blinded which means that patients and the study doctor will not know which treatment has been assigned. Patients in this study will be allowed treatment with stable doses of oral aminosalicylates, oral corticosteroids, immunosupressants and antibiotics for the treatment of Crohn's disease.

After 12 weeks in the study until the end of the study, patients who do not have an improvement in their Crohns disease symptoms will have the option to enter a long term active treatment study. Participants who discontinued the study anytime or completed the study at Week 52 were then observed for an additional 4 weeks.

ReferenceCitation: Gold SL, Cohen-Mekelburg S, Schneider Y, Steinlauf A. Perianal Fistulas in Patients With Crohn's Disease, Part 2: Surgical, Endoscopic, and Future Therapies. Gastroenterol Hepatol (N Y). 2018 Sep;14(9):521-528.

ReferenceCitation: Sands BE, Feagan BG, Sandborn WJ, Schreiber S, Peyrin-Biroulet L, Frédéric Colombel J, Rossiter G, Usiskin K, Ather S, Zhan X, D'Haens G. Mongersen (GED-0301) for Active Crohn's Disease: Results of a Phase 3 Study. Am J Gastroenterol. 2020 May;115(5):738-745. doi: 10.14309/ajg.0000000000000493.

family: Sands

full_name: Bruce E. Sands

given: Bruce E.

family: Feagan

full_name: Brian G. Feagan

given: Brian G.

family: Sandborn

full_name: William J. Sandborn

given: William J.

family: Schreiber

full_name: Stefan Schreiber

given: Stefan

family: Peyrin-Biroulet

full_name: Laurent Peyrin-Biroulet

given: Laurent

family: Frédéric Colombel

full_name: Jean Frédéric Colombel

given: Jean

family: Rossiter

full_name: Guillermo Rossiter

given: Guillermo

family: Usiskin

full_name: Keith Usiskin

given: Keith

family: Ather

full_name: Shabana Ather

given: Shabana

family: Zhan

full_name: Xiaojiang Zhan

given: Xiaojiang

family: D'Haens

full_name: Geert D'Haens

given: Geert

journal_name: American Journal of Gastroenterology

publisher: Ovid Technologies (Wolters Kluwer Health)

publisher_dissemination: Wolters Kluwer Health

publisher_group: Wolters Kluwer Health

publisher_normalized: Wolters Kluwer Health

lead_sponsor: Celgene

location_country:
Finland
Malaysia
Greece
Romania
Australia
Belgium
Russian Federation
Denmark
Ukraine
Croatia
France
Poland
Slovakia
Norway
Canada
Korea, Republic of
Turkey
Sweden
Switzerland
Netherlands
Bulgaria
Hungary
Portugal
Germany
United States
United Kingdom
Italy
Austria
Serbia
Czechia
Israel
New Zealand
Spain
Estonia
Latvia

location_facility: Praxis fuer Gastroenterologie Dr Ehehal Dr Helmstaedter

location_facility: Groupement Hospitalier Sud Hopital Bicetre

location_facility: Gaziantep University Medical Faculty Sahinbey Educational Research Hospital

location_facility: Florida Medical Research - Southeastern Integrated Medical

location_facility: Seconda Universita Degli Studi Di Napoli

location_facility: Fakultna nemocnica s poliklinikou F. D. Roosevelta

location_facility: Premier Medical Group of the Hudson Valley PC

location_facility: IRCCS Ospedale Casa Sollievo della Sofferenza

location_facility: Zentrum fuer HIV und Hepatogastroenterologie GmbH

location_facility: The Catholic University of Korea, St.Vicent's Hospital

location_facility: Fejer Megyei Szent Gyorgy Egyetemi Oktato Korhaz

location_facility: CI of SRC Sumy RCH Dept of Rheumatology Sumy SU MI

location_facility: Gastroenterology Associates of Tidewater

location_facility: Tel Aviv Sourasky Medical Center Department of Hematology

location_facility: Istanbul University Cerrahpasa Medical Faculty Hospital

location_facility: Stavanger Unviversitetssjukehus Helse Stavanger HF

location_facility: SP ZOZ Wojewodzki Szpital Zespolony im. J. Sniadeckiego

location_facility: University Hospitals Case Medical Center

location_facility: Klinikum Mannheim GmbH Universitaetsklinikum

location_facility: Azienda Ospedaliero Universitaria Consorziale Policlinico di Bari

location_facility: University of Southern California Medical Center

location_facility: Anticancer Hospital of Thessaloniki THEAGENIO

location_facility: Azienda Ospedaliera Universitaria OO. RR. S. Giovanni di Dio e Ruggi dAragona

location_facility: Oklahoma University Health Sciences Center

location_facility: Centre de sante et de services sociaux Champlain Charles Le Moyne

location_facility: Fakultna nemocnica s poliklinikou Zilina

location_facility: Soukroma Gastroenterologicka ambulance a endoskopie

location_facility: Markhot Ferenc Oktato Korhaz es Rendelointezet

location_facility: Kocaeli Derince Training and Research Hospital

location_facility: University of Washington School of Medicine

location_facility: Charite Universitaetsmedizin Berlin Campus Benjamin Franklin

location_facility: Universitaetsklinikum Carl Gustav Carus TU Dresden

location_facility: SzSzB Megyei Korhazak es Egyetemi Oktatokorhaz

location_facility: Clinical Research Institute of Michigan, LLC

location_facility: Haydarpasa Numune Training and Research Hospital

location_facility: University Hospital of South Manchester NHS Foundation Trust -Wythenshawe Hospital - North West Lung

location_facility: The Feinstein Institute for Medical Research PRIME

location_facility: Krajska zdravotni, a.s. - Masarykova nemocnice v Usti nad La

location_facility: M.I. Pyrogov VRCH Dept of Gastroenterology M.I. Pyrogov VNMU

location_facility: SBHI of NN region RCH of NN n.a. N.A.Semashko

location_facility: Crohn-Colitis Zentrum Bern Gemeinschaftspraxis Balsiger Seibold und Partner

location_facility: Communal Institution City Policlinic #20 Cabinet of Gastroenterology

location_facility: Lviv Municipal City Clinical Hospital #5 Dept of Therapy D.Halytsky Lviv NMU

location_facility: Istanbul Medeniyet Uni Goztepe Training&Res Hosp

location_facility: Pauls Stradins Clinical University Hospital

location_facility: North Shore Long Island Jewish Health System

location_facility: Wake Forest University Baptist Medical Center

location_facility: Azienda Ospedaliera Universitaria Policlinico Tor Vergata

location_facility: McMaster University Health Sciences Center

location_facility: Yeditepe University Medical School Hospital

location_facility: Azienda Ospedaliera San Camillo Forlanini

location_facility: Southwest Gastroenterology Associates PC

location_facility: Atlanta Gastroenterology Associates, LLC

location_facility: Henry Ford Medical Center - New Center One

location_facility: KH der Barmherzigen Brüder St.Veit an der Glan

location_facility: GI L.T.Malaya Therapy National Institute of the NAMS of Ukraine

location_facility: Riga East Clinical University Hospital clinic Gailezers

location_facility: Spitalul Clinic Judetean de Urgente Sf. Spiridon

location_facility: Hospital Universitari Germans Trias i Pujol

location_facility: LKH - Universitätsklinikum der PMU Salzburg

location_facility: Szent Janos Korhaz es Eszak-budai Egyesitett Korhazak

location_facility: Clinsante S.C. Osrodek Badan Klinicznych

location_facility: Berufsgenossenschaftliches Universitaetsklinikum Bergmannsheil GmbH

location_facility: Marmara University Pendik Training and Research Hospital

location_facility: Centro Hospitalar do Alto Minho - Unidade Local de Saúde do Alto Minho, EPE

location_facility: Niepubliczny Zaklad Opieki Zdrowotnej POLIMEDICA

location_facility: Texas Digestive Disease Consultants - Dallas

location_facility: Ternopil City Communal Emergency Medical Care Hospital

location_facility: Szent Pantaleon Korhaz Rendelointezet Dunaujvaros

location_facility: Azienda Ospedaliera Universitaria Policlinico G Martino

location_facility: NonState Healthcare Institution Central Clinical Hospital, Samara station JSC Russian Railways

location_facility: Gastroenterology Associates of Western Michigan PLC

location_facility: University of Wisconsin Hospital and Clinics

location_facility: SRI of Invalid Rehabilitation EST Complex of Vinnytsia M.I.Pyrogov NMU MOHU

location_facility: SBIH of Perm territory City Clinical Hospital 2 na Fedor Khristoforovich Gral

location_facility: Hospital Universitario Puerta de Hierro Majadahonda

location_facility: M.V. Sklifosovskyi Poltava RCH Outpatient UMSA HSEIU Ukrainian Medical Stomatological Academy

location_facility: SPZOZ Uniwersytecki Szpital Kliniczny im. Wojskowej Akademii Medycznej - Centralny Szpital Weteranow

location_facility: Via Christi Research a division of Via Christi Hospitals Wichita Inc

location_facility: University General Hospital of Alexandroupolis

location_facility: CI Zaporizhzhia Regional Clinical Hospital of ZRC

location_facility: Fondazione IRCCS CA Granda Ospedale Maggiore Policlinico

location_facility: Toronto Digestive Disease Associates Inc

location_facility: SEIHPE Rostov State Medical University of MoH of RF

location_facility: Universitaetsklinikum FreiburgInnere Med.1, Haematologie

location_facility: University of North Carolina at Chapel Hill

location_facility: Seoul National University Bundang Hospital

location_facility: The Methodist Hospital Research Institute

location_facility: Lviv Regional Clinical Hospital D Halytskyi Lviv NMU

location_facility: McGill University Health Centre Glen Site Royal Victoria Hospital

location_facility: Nemocnica s poliklinikou sv Barbory Roznava a s

location_facility: BHI of Omsk region Clinical Oncology Dispensary

location_facility: Nottingham University Hospitals Queens Medical Centre

location_facility: Hospital da Senhora da Oliveira Guimaraes

location_facility: SBEI of HPE Omsk State Medical Academy Ministry of healthcare of RF

location_facility: University of Texas Health Science Center at Houston

location_facility: General Hospital of Nikaea Piraeus Ag. Panteleimon

location_facility: Azienda Ospedaliera Universitaria Federico II

location_facility: Policlinico Universitario Agostino Gemelli

location_facility: University General Hospital of Heraklion

location_facility: University of California at San Francisco

location_facility: New York - Presbyterian/Weill Cornell Medical Center

location_facility: General Hospital of Heraklion Benizeleio Pananeio

location_facility: Mercy Clinic East Communities d/b/a Mercy Health Research

location_facility: RCI Chernivtsi Regional Clinical Hospital Dept of Surgery Bukovinian SMU

location_facility: Medical Research Center of Connecticut LLC

location_facility: Internistische Gemeinschaftspraxis f. Verdauungs- und Stoffwechselerkrankungen

location_facility: Azienda Ospedaliera Universitaria Policlinico Sant Orsola Malpighi

location_facility: Hopital Maisonneuve Rosemont dba CIUSSS de lEst de lIle de Montreal

location_facility: CHA Bundang Medical Center CHA University

location_facility: Ukrainian-German Antiulcer Gastroenterological Center BYK-Kyiv LLC

location_facility: Asheville Gastroenterology Associates, PA

location_facility: Johns Hopkins University School of Medicine

location_facility: Indywidualna Praktyka Lekarska Maciej Zymla

location_facility: SBI of Healthcare of Leningrad region Clinical Interregional Hospital of Tosno

location_facility: Irkutsk State Medical Academy of Continuing Education

location_facility: Medizinisches Zentrum Klinikum Lueneburg

location_facility: Severance Hospital, Yonsei University Health System

location_facility: Ordination Dr. Thomas Haas Darmpraxis Salzburg

location_facility: SBHI of Yaroslavl Region Clinical Hospital 8

location_facility: London Health Science Center U. Hospital

location_facility: Univerzitna nemocnica Bratislava Nemocnica Ruzinov

location_facility: RSHI State Novosibirsk Regional Clinical Hospital

location_facility: Texas Digestive Disease Consultants Dallas

location_facility: Azienda Ospedaliero Universitaria Pisana

location_facility: Staedtisches Klinikum Braunschweig gGmbH Standort Salzdahlumer

location_facility: Centro Hospitalar E Universitario de Coimbra EPE

location_facility: Texas Digestive Disease Consultants - Southlake

location_facility: Northwestern University-Feinberg School of Medicine

location_facility: Groupe Hospitalier Sud Hopital Haut Leveque USN

location_facility: Hospital Clinic I Provincial de Barcelona

location_facility: NYU Langone Nassau Gastroenterology Associates

location_facility: FSBI Scientific Research Institute of Physyology and Basic Medicine under the SB of RAMS

location_facility: General Hospital of Thessaloniki Hippokration

location_facility: University of Pennsylvania School of Medicine

location_facility: SI Branch CH of Zaporizhzhia Station-2 of SE Prydniprovska Railway Dept of Surgery Zaporizhzhia SMU

location_facility: SI Republican Clinical Hospital of the MOHU Dept of Gastroenterology O.O.Bogomolets NMU

location_facility: Treatment-Diagnostic Center of Private Enterprise of PMF Atsynus

location_facility: Universitaetsklinikum Schleswig Holstein Campus Kiel

location_facility: SBEIHPE Novosibirsk State Medical University

location_facility: Penn State University Milton S Hershey Medical Center

location_facility: Clinexpert Egeszsegugyi Szolg es Ker Kft

location_facility: Gastroeneterologicka ambulancia MUDr. Peter Hegyi s.r.o.

location_facility: Private Educational Institution of Higher Education Medical university REAVIZ