title: A Phase 3, Multicenter, Randomized, Doubleblind, Placebo-controlled, Parallel Group Study, Followed by an Active-treatment Phase to Evaluate the Efficacy and Safety of Apremilast (CC-10004) in the Treatment of Subjects With Active Behcet's Disease

summary: The main objective of this study is to evaluate the efficacy and safety of apremilast in the treatment of oral ulcers in adults with active Behçet's disease (BD).

ReferenceCitation: Hatemi G, Mahr A, Ishigatsubo Y, Song YW, Takeno M, Kim D, Melikoğlu M, Cheng S, McCue S, Paris M, Chen M, Yazici Y. Trial of Apremilast for Oral Ulcers in Behçet's Syndrome. N Engl J Med. 2019 Nov 14;381(20):1918-1928. doi: 10.1056/NEJMoa1816594.

name: From Istanbul University–Cerrahpaşa, Cerrahpaşa Medical School and Behçet’s Disease Research Center, Istanbul, Turkey (G.H., M.M.); Hospital Saint-Louis, University Paris Diderot, Paris (A.M.); Yokohama City University Graduate School of Medicine, Yokohama (Y.I.), and Nippon Medical School, Graduate School of Medicine, Tokyo (M.T.) — both in Japan; Seoul National University and Seoul National University Hospital (Y.-W.S.) and Yonsei University College of Medicine and Severance Hospital (D.K.), Seoul,...

family: Hatemi

full_name: Gülen Hatemi

given: Gülen

family: Mahr

full_name: Alfred Mahr

given: Alfred

family: Ishigatsubo

full_name: Yoshiaki Ishigatsubo

given: Yoshiaki

family: Song

full_name: Yeong-Wook Song

given: Yeong-Wook

family: Takeno

full_name: Mitsuhiro Takeno

given: Mitsuhiro

family: Kim

full_name: Doyoung Kim

given: Doyoung

family: Melikoğlu

full_name: Melike Melikoğlu

given: Melike

family: Cheng

full_name: Sue Cheng

given: Sue

family: McCue

full_name: Shannon McCue

given: Shannon

family: Paris

full_name: Maria Paris

family: Chen

full_name: Mindy Chen

given: Mindy

family: Yazici

full_name: Yusuf Yazici

given: Yusuf

journal_name: New England Journal of Medicine

oa_host_type: publisher

evidence: open (via free article)

publisher: Massachusetts Medical Society

publisher_dissemination: Massachusetts Medical Society

publisher_group: Massachusetts Medical Society

publisher_normalized: Massachusetts Medical Society

title: Trial of Apremilast for Oral Ulcers in Behçet’s Syndrome

ipd_sharing_description: De-identified individual patient data for variables necessary to address the specific research question in an approved data sharing request

lead_sponsor: Amgen

location_country:
Italy
United States
Lebanon
France
Japan
Greece
Israel
Turkey
Germany
Korea, Republic of

location_facility: Medical Hospital of Tokyo Medical and Dental University

location_facility: Japanese Red Cross Society Himeji Hospital

location_facility: University of California Davis Medical Center

location_facility: University of Pennsylvania Health Systems

location_facility: Severance Hospital, Yonsei University Health System

location_facility: St Marianna University School of Medicine Hospital

location_facility: Azienda Ospedaliero Universitaria Careggi

location_facility: Northwestern University Feinberg School of Medicine

location_facility: American University of Beirut Medical Center

location_facility: Ippokratio General Hospital of Thessaloniki

location_facility: University of Occupational and Environmentall Health

location_facility: Arizona Arthritis and Rheumatology Research, PLLC

location_facility: Istanbul Universitesi Cerrahpasa Tip Fakultesi

location_facility: Cukurova University Medical Faculty Balcali Hospital


ReferenceType: derived

ReferenceCitation: Blauvelt A, Teixeira HD, Simpson EL, Costanzo A, De Bruin-Weller M, Barbarot S, Prajapati VH, Lio P, Hu X, Wu T, Liu J, Ladizinski B, Chu AD, Eyerich K. Efficacy and Safety of Upadacitinib vs Dupilumab in Adults With Moderate-to-Severe Atopic Dermatitis: A Randomized Clinical Trial. JAMA Dermatol. 2021 Sep 1;157(9):1047-1055. doi: 10.1001/jamadermatol.2021.3023.

name: Oregon Medical Research Center, Portland

family: Blauvelt

full_name: Andrew Blauvelt

given: Andrew

sequence: first

family: Teixeira

full_name: Henrique D. Teixeira

given: Henrique D.

sequence: additional

name: Department of Dermatology, Oregon Health & Science University, Portland

family: Simpson

full_name: Eric L. Simpson

given: Eric L.

name: Dermatology Unit, Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy

name: Humanitas Clinical and Research Center, Scientific Institute for Research, Hospitalization and Healthcare, Rozzano, Italy

family: Costanzo

full_name: Antonio Costanzo

given: Antonio

name: Department of Dermatology and Allergology, University Medical Center Utrecht, Utrecht, the Netherlands

family: De Bruin-Weller

full_name: Marjolein De Bruin-Weller

given: Marjolein

name: Department of Dermatology, Nantes Université, Centre Hospitalier Universitaire de Nantes, Nantes, France

family: Barbarot

full_name: Sebastien Barbarot

given: Sebastien

name: Division of Dermatology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada

name: Division of Community Pediatrics, Department of Pediatrics, University of Calgary, Calgary, Alberta, Canada

name: Division of Pediatric Rheumatology, Department of Pediatrics, University of Calgary, Calgary, Alberta, Canada

name: Skin Health & Wellness Centre, Calgary, Alberta, Canada

name: Dermatology Research Institute, Calgary, Alberta, Canada

family: Prajapati

full_name: Vimal H. Prajapati

given: Vimal H.

name: Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois

name: Medical Dermatology Associates of Chicago, Chicago, Illinois

family: Lio

full_name: Peter Lio

given: Peter

family: Hu

full_name: Xiaofei Hu

given: Xiaofei

family: Wu

full_name: Tianshuang Wu

given: Tianshuang

family: Liu

full_name: John Liu

given: John

family: Ladizinski

full_name: Barry Ladizinski

given: Barry

family: Chu

full_name: Alvina D. Chu

given: Alvina D.

name: Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden

name: Department of Dermatology and Allergy, Technical University of Munich, Munich, Germany

family: Eyerich

full_name: Kilian Eyerich

given: Kilian

bso_classification: Medical research

datasource: user

genre: journal-article

genre_raw: journal-article

journal_name: JAMA Dermatology

oa_colors: green other

oa_host_type: publisher;repository

evidence: open (via free pdf)

host_type: publisher

license: cc-by-nc-nd

license_normalized: cc-by-nc-nd

version: publishedVersion

evidence: oa repository (via pmcid lookup)

host_type: repository

license_normalized: no license

repository_normalized: PubMed Central

publisher: American Medical Association (AMA)

publisher_dissemination: American Medical Association

publisher_group: American Medical Association

publisher_normalized: American Medical Association

design_allocation: Randomized

intervention_type: Drug

status: Completed

study_start_date_type: Actual

study_type: Interventional

ipd_sharing_description: AbbVie is committed to responsible data sharing regarding the clinical trials we sponsor. This includes access to anonymized, individual and trial-level data (analysis data sets), as well as other information (e.g., protocols and clinical study reports), as long as the trials are not part of an ongoing or planned regulatory submission. This includes requests for clinical trial data for unlicensed products and indications.

lead_sponsor: AbbVie

enrollment_type: Actual

primary_purpose: Treatment

location_country:
Finland
Malaysia
Australia
Taiwan
Ukraine
Croatia
France
Poland
Norway
Canada
Sweden
Netherlands
Singapore
Hungary
Ireland
United States
Germany
United Kingdom
Italy
Czechia
Israel
New Zealand
Spain

acronym: Heads Up

location_facility: DermaPlus - Poliklinika za dermatologiju i venerologiju /ID# 209935

location_facility: China Medical University Hosp /ID# 209770

location_facility: Hospital Universitario y Politecnico La Fe /ID# 207064

location_facility: Debreceni Egyetem Klinikai Kozpont /ID# 210893

location_facility: Progressive Medical Research /ID# 211994

location_facility: University of Arkansas for Medical Sciences /ID# 211688

location_facility: Royal Alex Childrens County Hospital /ID# 209709

location_facility: ME "Rivne Regional Dermatology and Venereology Dispensary" of RRC /ID# 210434

location_facility: Universitetssykehuset N-Norge, Harstad /ID# 209105

location_facility: Hospital Universitario Dr. Negrin /ID# 208969

location_facility: Meridian Clinical Research Dermatology /ID# 213251

location_facility: St Vincent's University Hosp /ID# 208441

location_facility: Szpital Uniwersytecki nr 1 im. dr. A. Jurasza w Bydgoszczy /ID# 211103

location_facility: Dermatology Research Associates /ID# 209097

location_facility: Dr. Wei Jing Loo Medicine Prof /ID# 211400

location_facility: Hospital Pakar Sultanah Fatimah /ID# 210185

location_facility: A.O. Policlinico Sant'Orsola Malpighi /ID# 209111

location_facility: Beacon Clinical Research, LLC /ID# 209280

location_facility: Sneeze, Wheeze, & Itch Associates, LLC /ID# 212058

location_facility: Epiphany Dermatology - Fort Worth /ID# 211187

location_facility: Chung Shan Medical University /ID# 208311

location_facility: Miami Dermatology and Laser Institute /ID# 212938

location_facility: Holdsworth House Medical Practice /ID# 214565

location_facility: Universitaetsklinikum Frankfurt /ID# 210934

location_facility: The Community Research of South Florida /ID# 211145

location_facility: IBD Center - IRCCS Istituto Clinico Humanitas /ID# 215726

location_facility: Naftalan - Specijalna bolnica za medicinsku rehabilitaciju /ID# 209937

location_facility: Somogy Megyei Kaposi Mor Oktat /ID# 210149

location_facility: Dartmouth-Hitchcock Medical Center /ID# 213727

location_facility: Hospital Universitario Arnau Vilanova /ID# 207065

location_facility: Dre Angelique Gagne-Henley M.D. inc. /ID# 209498

location_facility: Complejo Hospitalario Universitario de Pontevedra /ID# 207139

location_facility: Florida International Rsrch cr /ID# 211562

location_facility: Hautklinik Klinikum Darmstadt /ID# 210938

location_facility: Taipei Municipal Wan Fang Hospital /ID# 209987

location_facility: CHRU Lille - Hopital Claude Huriez /ID# 209317

location_facility: Nemocnice Jihlava, prispevkova organizace /ID# 209131

location_facility: Medical Dermatology Associates of Chicago /ID# 210265

location_facility: Clinical Research Partners, LLC /ID# 212262

location_facility: National University Hospital /ID# 208774

location_facility: Dermatology Research Institute Inc. /ID# 210942

location_facility: California Allergy and Asthma Medical Group /ID# 213680

location_facility: Georgia Pollens Clinical Research Centers, Inc /ID# 211092

location_facility: National Taiwan University Hospital /ID# 208309

location_facility: Guy's and St Thomas' NHS Found /ID# 208881

location_facility: Universitetssykehuset N-Norge, Tromso /ID# 209103

location_facility: Dr. Chih-ho Hong Medical Inc. /ID# 211032

location_facility: Northwestern University Feinberg School of Medicine /ID# 208680

location_facility: Allergy, Asthma & Immunology Associates, PC /ID# 213481

location_facility: Klinicki bolnicki centar Zagreb /ID# 209976

location_facility: Clinical Research Solutions, LLC /ID# 212542

location_facility: Oregon Health and Science University /ID# 208809

location_facility: Keski-pohjanmaa Central Hospital /ID# 209534

location_facility: Centre Hospitalier Universitaire de Nice - Hopital l'Archet 2 /ID# 213374

location_facility: University Hospital Waterford /ID# 208442

location_facility: Universitair Medisch Centrum Utrecht /ID# 208579

location_facility: Sugar Land Allergy, Asthma, and Immunology Center /ID# 211153

location_facility: Karolinska University Hospital /ID# 207909

location_facility: Military Hospital of Military-Medical Clinical Center of Southern Region /ID# 210435

location_facility: Forest Hills Dermatology Group /ID# 209249

location_facility: Cardiff & Vale University Health Board /ID# 209745

location_facility: Hopital Larrey - CHU de Toulouse /ID# 208976

location_facility: Universitair Medisch Centrum Groningen /ID# 208583

location_facility: Royalderm Agnieszka Nawrocka /ID# 211015

location_facility: ClinicMed Daniluk, Nowak Sp.j. /ID# 211112

location_facility: Oregon Medical Res Center PC /ID# 208807

location_facility: Wellington Hospital (Capital and Coast District Health Board) /ID# 215001

location_facility: Medical University of South Carolina /ID# 211054

location_facility: Hospital Universitario de Bellvitge /ID# 207063

location_facility: Policlinico Univ Tor Vergata /ID# 209112

location_facility: Niakosari Medicine Professional Corporation /ID# 211401

location_facility: Klinika Ambroziak Sp. z o.o. /ID# 207443

location_facility: Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico /ID# 210632

location_facility: Kyiv City Clinical Skin and Venereal Hospital /ID# 210755

location_facility: Ospedale San Giovanni di Dio /ID# 209109

location_facility: Universitatsklinikum Munster /ID# 210935

location_facility: Integrated Clinical Research LLC /ID# 208831

location_facility: Medizinische Hochschule Hannover /ID# 210939

location_facility: Clinical Research Trials of Florida, Inc. /ID# 210751

location_facility: Pecsi Tudomanyegyetem Klinikai l.sz. Belgyogyaszati Klinika /ID# 210892

location_facility: Clinical Research Institute, Inc /ID# 210852

ipd_sharing: Yes

study_completion_date_type: Actual

type: EudraCT Number

source: euctr

title: A Phase 3b Multicenter, Randomized, Double-Blind, Double-Dummy, Active Controlled Study Comparing the Safety and Efficacy of Upadacitinib to Dupilumab in Adult Subjects With Moderate to Severe Atopic Dermatitis

summary: This is a phase 3, randomized, multi-center study that will evaluate upadacitinib versus dupilumab in adults (18-75 years of age) with moderate to severe atopic dermatitis (AD) who are candidates for systemic therapy. The study is comprised of a 35-day screening period, a 24-week blinded treatment period, and a 12-week follow-up period.

lead_sponsor_type: industriel

status_simplified: Completed


ReferenceCitation: Greener T, Boland K, Milgrom R, Ben-Bassat O, Steinhart AH, Silverberg MS, Narula N. Higher adalimumab maintenance regimen is more effective than standard dose in anti-TNF experienced Crohn's disease patients. Eur J Gastroenterol Hepatol. 2021 Oct 1;33(10):1274-1279. doi: 10.1097/MEG.0000000000002250.

family: Greener

full_name: Tomer Greener

given: Tomer

family: Boland

full_name: Karen Boland

given: Karen

family: Milgrom

full_name: Raquel Milgrom

given: Raquel

family: Ben-Bassat

full_name: Ofer Ben-Bassat

given: Ofer

family: Steinhart

full_name: A. Hillary Steinhart

given: A. Hillary

family: Silverberg

full_name: Mark. S. Silverberg

given: Mark. S.

family: Narula

full_name: Neeraj Narula

given: Neeraj

journal_name: European Journal of Gastroenterology & Hepatology

publisher: Ovid Technologies (Wolters Kluwer Health)

publisher_dissemination: Wolters Kluwer Health

publisher_group: Wolters Kluwer Health

publisher_normalized: Wolters Kluwer Health

title: Higher adalimumab maintenance regimen is more effective than standard dose in anti-TNF experienced Crohn’s disease patients

location_country:
Italy
Austria
United States
Switzerland
Netherlands
Germany
France
Czechia
Poland
Israel
Slovakia
Romania
Hungary
Belgium
Puerto Rico
Spain
Denmark
Canada
United Kingdom
Ukraine

location_facility: Montreal General Hospital - McGill University Health Center /ID# 119025

location_facility: Kyiv City Clinical Hospital No.8 /ID# 126232

location_facility: Charlotte Gastroenterology and Hepatology, PLLC /ID# 119041

location_facility: Digestive Health Specialists of the Southeast /ID# 122483

location_facility: CHU Amiens-Picardie Site Sud /ID# 126237

location_facility: Consultants for Clinical Res /ID# 119052

location_facility: Salvo-san Ciobanca SRL / Medicina Interna /ID# 126224

location_facility: Northwestern University Feinberg School of Medicine /ID# 119043

location_facility: Private Practice - Dr. Michael R. MroB Dipl. med. S. Schache /ID# 126257

location_facility: CHU NANCY - Hopital Brabois Adultes /ID# 127742

location_facility: Hospital Universitario Puerta de Hierro, Majadahonda /ID# 140425

location_facility: Public Institution Kherson City Clinical Hospital named after le.le. Karabelesha /ID# 127754

location_facility: Lviv Regional Clinical Hospital /ID# 126234

location_facility: Azienda Ospedaliera di Padova /ID# 126267

location_facility: Magyar Elhizastudomanyi KKft. /ID# 126276

location_facility: School of Medicine University of Puerto Rico-Medical Science Campus /ID# 137735

location_facility: State Institution L. T. Malaya Therapy National Institution of NAMS of Ukraine /ID# 127753

location_facility: CHU de Saint-Etienne, Hopital Nord /ID# 134450

location_facility: Gastroenterology Group Naples /ID# 122493

location_facility: Medizinische Universitat Innsbruck,Universitatsklinik fur Innere Medizin 1 /ID# 126249

location_facility: Gastroenterologicke centrum ASSIDUO a IBD centrum /ID# 126262

location_facility: Universitaetsklinikum Schleswig-Holstein /ID# 126260

location_facility: IBD Center - IRCCS Istituto Clinico Humanitas /ID# 126226

location_facility: Winship Cancer Institute of Emory University /ID# 136851

location_facility: Norfolk and Norwich Univ Hosp /ID# 126197

location_facility: Hepato-Gastroenterologie HK s.r.o. /ID# 126269

location_facility: Soroka University Medical Center /ID# 126243

location_facility: Krankenhaus der Barmherzigen Bruder /ID# 126270

location_facility: Gastroenterology Institute, Division of Medicine /ID# 126245

location_facility: Guy's and St Thomas' NHS Found /ID# 144366

location_facility: Froedtert Memorial Lutheran Hospital /ID# 119081

location_facility: Medizinische Universitat Wien /ID# 126279

location_facility: Centrul Medical de Diagnostic si Tratament Ambulator Neomed SRL /ID# 126277

location_facility: Birmingham Gastroenterology Associates O.C /ID# 137282

location_facility: Centrum Medyczne sw. Lukasza Sp. z o.o. /ID# 126271

location_facility: KO-Med Centra Kliniczne Pulawi /ID# 126278

location_facility: Winnipeg Regional Health Authority /ID# 119015

location_facility: University Hospital Southampton NHS Fundation Trust /ID# 126225

location_facility: Hull University Teaching Hospitals NHS Trustust /ID# 126265

location_facility: Gastroenterologicka ambulancia /ID# 137964

location_facility: Moore UC San Diego Cancer Center /ID# 119053

location_facility: Academisch Medical center Amsterdam /ID# 126227

location_facility: Erlanger Institute for Clinical Research /ID# 129008

location_facility: Israelitisches Krankenhaus Hamburg /ID# 136549

location_facility: New River Valley Research Inst /ID# 127807

location_facility: Vseobecna Nemocnica s poliklinikou Lucenec n.o. /ID# 127748

location_facility: Nemocnice Ceske Budejovice a.s. /ID# 126266

location_facility: Ctr for Digest and Liver Dis /ID# 119040

location_facility: Investigative Clinical Research /ID# 119033

location_facility: Texas Digestive Disease Consultants - Southlake /ID# 137283

location_facility: Centrum.Medyczne. Szpital Swietej Rodziny /ID# 137974

location_facility: NYU Langone Long Island Clinical Research Associates /ID# 119035

location_facility: Pecsi Tudomanyegyetem Klinikai l.sz. Belgyogyaszati Klinika /ID# 137895

location_facility: Fondazione di Religione e di Culto Casa Sollievo della Sofferenza /ID# 129856

location_facility: Hospital Clinico Universitario Lozano Blesa /ID# 126252

location_facility: University of Michigan Health Systems /ID# 119076

location_facility: Toronto Digestive Disease Asso /ID# 119019

location_facility: Krajska zdravotni a.s. Masarykova nemocnice v Usti nad Labem o.z. /ID# 138331

location_facility: University of Calgary Cumming School of Medicine Adult Cystic Fibrosis Clinic /ID# 119017

location_facility: Hospital Clinico Universitario San Carlos /ID# 126253

location_facility: The Royal Wolverhampton NHS Tr /ID# 126201

location_facility: Medical University of South Carolina /ID# 138122

location_facility: Asklepios Westklinikum Hamburg /ID# 126275

location_facility: Wake Research Associates, LLC /ID# 119029

location_facility: Carle Foundation Hospital Digestive Health Research Center /ID# 136008

location_facility: Centre Hospitalier Universitaire de Grenoble - Hopital Michallon /ID# 126200

location_facility: Complejo Hospitalario Universitario de Pontevedra /ID# 138126

location_facility: Minnesota Gastroenterology, P. A. /ID# 137280

location_facility: Centrum Endoskopii Zabiegowej /ID# 126272

location_facility: Wisconsin Center for Advanced Research, a division of GI Associates, LLC /ID# 119036

location_facility: Commonwealth Clinical Studies /ID# 136850

location_facility: The Oregon Clinic, Gastroenterology - West /ID# 135272

location_facility: Universitatsklinikum Magdeburg /ID# 126256

location_facility: UOSD - Azienda Ospedaliera San Camillo Forlanini /ID# 127745

location_facility: Policlinico Agostino Gemelli /ID# 127746

location_facility: Cabinet Medical Dr. Fratila SRL /ID# 126247

location_facility: Kansas City Research Institute /ID# 119034

location_facility: Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico /ID# 126221

location_facility: KH der Elisabethinen Linz GmbH /ID# 126280

location_facility: Gastroenterology Associates of Central Georgia, LLC /ID# 119056

location_facility: MGG Group Co, Inc.Chevy Chase Clinical Research /ID# 119042

location_facility: Shafran Gastroenterology Ctr /ID# 119057

location_facility: Hospital Parc Tauli de Sabadell /ID# 138124

location_facility: Public Institution 6th City Clinical Hospital /ID# 126236

location_facility: Texas Digestive Disease Consultants - Dallas /ID# 138121

location_facility: Hospital Universitario de Girona Doctor Josep Trueta /ID# 137976

location_facility: Rocky Mountain Gastroenterology /ID# 119038

location_facility: Austin Institute for Clinical Research /ID# 125500

location_facility: Azienda Ospedaliera Spedali Civili /ID# 127744

location_facility: Charite Universitaetsmedizin Berlin /ID# 126196

location_facility: London Health Sciences Centre - University Hospital /ID# 119026

location_facility: Louisana Research Center, LLC /ID# 136749

location_facility: CHRU Lille - Hopital Claude Huriez /ID# 127743

title: A Multicenter, Randomized, Double-Blind Study to Evaluate Higher Versus Standard Adalimumab Dosing Regimens for Induction and Maintenance Therapy in Subjects With Moderately to Severely Active Crohn's Disease and Evidence of Mucosal Ulceration

summary: This study will evaluate higher versus standard adalimumab dosing regimens for induction and maintenance therapy in subjects with moderately to severely active Crohn's Disease and evidence of mucosal ulceration.


title: Understanding Outcomes With the EMBLEM™ S-ICD in Primary Prevention Patients With Low Ejection Fraction

acronym: UNTOUCHED

summary: This study assesses the 18-month incidence of inappropriate shocks in subjects implanted with the EMBLEM Subcutaneous Implantable Defibrillator (S-ICD) for primary prevention of sudden cardiac death. Devices are to be programmed with zone cutoffs at 200 bpm and 250 bmp in order to mimic the programming settings for transvenous ICDs in the MADIT RIT study. The incidence of inappropriate S-ICD shocks will be compared to the incidence of inappropriate shocks observed in the MADIT RIT study.

primary_purpose: Supportive Care

ReferenceType: background

ReferenceCitation: Moss AJ, Schuger C, Beck CA, Brown MW, Cannom DS, Daubert JP, Estes NA 3rd, Greenberg H, Hall WJ, Huang DT, Kautzner J, Klein H, McNitt S, Olshansky B, Shoda M, Wilber D, Zareba W; MADIT-RIT Trial Investigators. Reduction in inappropriate therapy and mortality through ICD programming. N Engl J Med. 2012 Dec 13;367(24):2275-83. doi: 10.1056/NEJMoa1211107. Epub 2012 Nov 6.

ReferenceCitation: Gold MR, Knops R, Burke MC, Lambiase PD, Russo AM, Bongiorni MG, Deharo JC, Aasbo J, El Chami MF, Husby M, Carter N, Boersma L. The Design of the Understanding Outcomes with the S-ICD in Primary Prevention Patients with Low EF Study (UNTOUCHED). Pacing Clin Electrophysiol. 2017 Jan;40(1):1-8. doi: 10.1111/pace.12994. Epub 2017 Jan 15.

ReferenceType: result

ReferenceCitation: Boersma LV, El-Chami MF, Bongiorni MG, Burke MC, Knops RE, Aasbo JD, Lambiase PD, Deharo JC, Russo AM, Dinerman J, Shaik N, Barr CS, Carter N, Appl U, Brisben AJ, Stein KM, Gold MR. Understanding Outcomes with the EMBLEM S-ICD in Primary Prevention Patients with Low EF Study (UNTOUCHED): Clinical characteristics and perioperative results. Heart Rhythm. 2019 Nov;16(11):1636-1644. doi: 10.1016/j.hrthm.2019.04.048. Epub 2019 May 10.

family: Boersma

full_name: Lucas V. Boersma

given: Lucas V.

family: El-Chami

full_name: Mikhael F. El-Chami

given: Mikhael F.

family: Bongiorni

full_name: Maria Grazia Bongiorni

given: Maria Grazia

family: Burke

full_name: Martin C. Burke

given: Martin C.

family: Knops

full_name: Reinoud E. Knops

given: Reinoud E.

family: Aasbo

full_name: Johan D. Aasbo

given: Johan D.

family: Lambiase

full_name: Pier D. Lambiase

given: Pier D.

family: Deharo

full_name: Jean Claude Deharo

given: Jean Claude

family: Russo

full_name: Andrea M. Russo

given: Andrea M.

family: Dinerman

full_name: Jay Dinerman

given: Jay

family: Shaik

full_name: Naushad Shaik

given: Naushad

family: Barr

full_name: Craig S. Barr

given: Craig S.

family: Carter

full_name: Nathan Carter

given: Nathan

family: Appl

full_name: Ursula Appl

given: Ursula

family: Brisben

full_name: Amy J. Brisben

given: Amy J.

family: Stein

full_name: Kenneth M. Stein

given: Kenneth M.

family: Gold

full_name: Michael R. Gold

given: Michael R.

journal_name: Heart Rhythm

oa_colors: green hybrid

evidence: open (via crossref license)

evidence: oa repository (via OAI-PMH title and first author match)

repository_institution: University College London - UCL Discovery

repository_normalized: UCL Discovery

ReferenceCitation: Gold MR, Lambiase PD, El-Chami MF, Knops RE, Aasbo JD, Bongiorni MG, Russo AM, Deharo JC, Burke MC, Dinerman J, Barr CS, Shaik N, Carter N, Stoltz T, Stein KM, Brisben AJ, Boersma LVA; UNTOUCHED Investigators*. Primary Results From the Understanding Outcomes With the S-ICD in Primary Prevention Patients With Low Ejection Fraction (UNTOUCHED) Trial. Circulation. 2021 Jan 5;143(1):7-17. doi: 10.1161/CIRCULATIONAHA.120.048728. Epub 2020 Oct 19.

name: Department of Medicine, Medical University of South Carolina, Charleston (M.R.G.).

name: Institute of Cardiovascular Science, University College of London, Barts Heart Centre and University College, London, United Kingdom (P.D.L.).

name: Department of Medicine, Emory University Hospital, Atlanta, GA (M.F.E.).

name: Department of Electrophysiology, Amsterdam University Medical Center, The Netherlands (R.E.K.).

name: Department of Cardiac Electrophysiology, Baptist Health Lexington, KY (J.D.A.).

name: Division of Cardiology, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy (M.G.B.).

name: Department of Medicine, Cooper Medical School of Rowan University, Camden, NJ (A.M.R.).

name: Cardiologie and Rythmologie Division, Centre hospitalier Universitaire La Timone Hospital, Marseille, France (J.C.D.).

name: CorVita Science Foundation, Chicago, IL (M.C.B.).

name: Heart Center Research, LLC, Huntsville, AL (J.D.).

name: Russells Hall Hospital, Dudley, United Kingdom (C.S.B.).

name: Boston Scientific Corporation, St Paul, MN (N,C., T.S., K.M.S., A.J.B.).

name: St Antonius Ziekenhuis, Nieuwegein Department of Cardiology, Nieuwegein, The Netherlands (L.V.B.).

location_country:
Italy
United States
Switzerland
Netherlands
Germany
France
Poland
Belgium
Puerto Rico
Spain
Denmark
Canada
United Kingdom

location_facility: Huntsville Hospital - The Heart Center, PC

location_facility: Cooper Hospital - University Medical Center

location_facility: Institut universitaire de Cardiologie et de Pneumologie de Quebec

location_facility: University of Iowa Hospitals and Clinics

location_facility: Cardiovascular Associates of the Delaware Valley

location_facility: Centralny Szpital Kliniczny Uniwerytetu Medycznego

location_facility: University of Southern California Hospital

location_facility: Sacred Heart Medical Center at Riverbend

location_facility: Strong Memorial Hospital of the University of Rochester

location_facility: Azienda Ospedaliero Universitaria Pisana

location_facility: Virginia Commonwealth University Health System

location_facility: Azienda Ospedaliera Universitaria Integrata di Verona

location_facility: Erasmus MC - University Medical Center Rotterdam

location_facility: Northern Indiana Research Alliance - Lutheran Hospital

location_facility: CardioVascular Institute of Michigan P.C.


type: Other Identifier

title: A Phase 2/3, Randomized, Double-blind, Placebo- and Active-controlled, Parallel-group, Multicenter Protocol to Evaluate the Efficacy and Safety of Guselkumab in Participants With Moderately to Severely Active Crohn's Disease

acronym: GALAXI

summary: The purpose of this study is to evaluate the clinical efficacy (GALAXI 1), clinical and endoscopic efficacy (GALAXI 2 and GALAXI 3) and safety of guselkumab in participants with Crohn's disease.

status: Recruiting

study_completion_date_type: Anticipated

enrollment_type: Anticipated

lead_sponsor: Janssen Research & Development, LLC

location_country:
Jordan
North Macedonia
Malaysia
Greece
Australia
Belgium
Russian Federation
Taiwan
Ukraine
Spain
Croatia
France
Japan
Lithuania
Poland
Slovakia
Canada
Korea, Republic of
Colombia
Chile
Saudi Arabia
Switzerland
Netherlands
Hungary
Puerto Rico
China
Portugal
Germany
United States
United Kingdom
Italy
Austria
Bosnia and Herzegovina
Brazil
Serbia
Lebanon
Czechia
Israel
Georgia
Tunisia
New Zealand
Belarus
Turkey
Latvia

location_facility: VA Caribbean Healthcare System - San Juan VA Medical Center

location_facility: Groupement Hospitalier Universitaire Ouest

location_facility: Azienda Ospedaliero Universitaria S.Maria Della Misericordia

location_facility: Szegedi Tud.Egyetem Szent-Gyorgyi Albert Klin. Közp.

location_facility: Lietuvos sveikatos mokslų universiteto ligoninė Kauno klinik

location_facility: KZ Khersonska Miska Klinichna Likarnia Im. Ye.Ie.Karabelesha

location_facility: The Second Affiliated Hospital of Zhejiang University

location_facility: National Hospital Organization Kure Medical Center and Chugoku Cancer Center

location_facility: Hopitaux Universitaires Paris Nord Val de Seine - Hopital Beaujon

location_facility: National Hospital Organization Mito Medical Center

location_facility: Israel Georgian medical research clinic Helsicore

location_facility: MNCE Zakarpatska Regional Clinical Hospital named after A Novak of Zakarpatska Regional Council

location_facility: Special hospital for Internal diseases, Oncomed system

location_facility: State Scientific Centre of Coloproctology

location_facility: Clinical Hospital #122 n.a. after L.G. Sokolov

location_facility: Military Hospital of Instruction of Tunis

location_facility: Shiga University of Medical Science Hospital

location_facility: Bekes Megyei Kozponti Korhaz Pandy Kalman Tagkorhaz

location_facility: Gastroenterology Associates of Tidewater

location_facility: Second Military Medical University (SMMU)

location_facility: Academisch Medisch Centrum Universiteit van Amsterdam

location_facility: 1 Wojskowy Szpital Kliniczny z Poliklinika SPZOZ w Lublinie

location_facility: University North Carolina at Chapel Hill

location_facility: Gastroenterologische Spezialpraxis - Berlin-Karlshorst

location_facility: Ospedale Molinette, AO Città della Salute e della Scienza di

location_facility: Centro Digestivo de Curitiba - Instituto de Pesquisa Clínica

location_facility: Istituto Clinico Humanitas Rozzano, IRCCS

location_facility: SE 'National institute therapy named L.T. Maloi NAMS of Ukraine'

location_facility: Hokkaido P.W.F.A.C. Sapporo-Kosei General Hospital

location_facility: ZhuJiang Hospital of Southern Medical University

location_facility: Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University

location_facility: Észak-Közép-budai Centrum, Új Szent János Kórház és Szakrendelő Budai Családközpontú

location_facility: City Hospital named after St. Martyr Elizabeth

location_facility: Policlinico S.Orsola Malpighi, AOU di Bologna

location_facility: Centro Hospitalar Lisboa Norte EPE - Hospital Pulido Valente

location_facility: LTD Unimed Kakheti- Telavi Referral Hospital

location_facility: H. Santo António - Centro Hospitalar do Porto

location_facility: Agaplesion Frankfurter Diakonie Kliniken GmbH, Markus Krankenhaus

location_facility: Atlantic Digestive Health Institute/ Atlantic IBD Center

location_facility: Mustafa Kemal University Research and Practise Hospital

location_facility: The First Affiliated Hospital of NanChang University

location_facility: First Affiliated Hospital of Gannan Medical University

location_facility: Ruijin Hospital, Shanghai Jiao Tong University

location_facility: Cukurova University Medical Faculty Balcali Hospital

location_facility: Clinical Research Institute of Michigan, LLC

location_facility: St.Petersburg State Medical University n.a.Pavlov

location_facility: Centro Hospitalar de Entre o Douro e Vouga, E.P.E

location_facility: University of Hong Kong-Shenzhen Hospital

location_facility: Ospedale L.Sacco, PU, ASST Fatebenefratelli Sacco

location_facility: National Hospital Organization Kyoto Medical Center

location_facility: King Abdul Aziz Medical City for National Guard Health Affairs

location_facility: LTD 'Georgia Archangel St. Michael Multiprofile Clinical Hospital'

location_facility: The Catholic University of Korea St. Vincent's Hospital

location_facility: GBOU VPO Rostov State Medical University

location_facility: Kaposi Mór Oktató Kórház, Kardiológiai Részleg

location_facility: Gastroenterology and Internal Medicine Research Institute (GIRI)

location_facility: Hôpitaux Universitaires de Strasbourg - Hôpital de Hautepierre

location_facility: American Universitty of Beirut Medical Center

location_facility: FSBI 'Scientific Research Institute of Clinical and Experimental Lymphology' of Siberian Branch

location_facility: Sun Yat-sen University - The Sixth Affiliated Hospital Guangdong Gastrointestinal Hospital

location_facility: Pauls Stradins Clinical University Hospital

location_facility: University Clinic of Gastroenterohepatology

location_facility: Japan Community Health Care Organization Saitama Medical Center

location_facility: The first hospital of China medical university

location_facility: Fundacao Faculdade Regional De Medicina De Sao Jose Do Rio Preto

location_facility: Twoja Przychodnia - Szczecinskie Centrum Medyczne

location_facility: The First Affiliated Hospital of Wenzhou Medical University

location_facility: Hospital de Clínicas de Porto Alegre/ HCPA / UFRGS

location_facility: Universidade Estadual Paulista 'Julio De Mesquita Filho'

location_facility: Hopital Regional Mohamed Tahar El Maamouri

location_facility: Medical Research and Practice Center Medbud of the Public Joint Stock Holding Company Kyivmiskbud

location_facility: The Second Affiliated Hospital of Chongqing Medical University

location_facility: Novgorod Regional Clinical Hospital n.a. N.A. Semashko

location_facility: UFRJ-Hospital Universitário Clementino Fraga Filho

location_facility: St Georges Hospital university medical centre

location_facility: Universita degli Studi di Padova - Azienda Ospedaliera di Padova

location_facility: CEMEC - Centro Multidisciplinar de Estudos Clínicos

location_facility: Sandwell and West Birmingham Hospitals NHS Trust-Sandwell Gene

location_facility: Sisli Etfal Egitim ve Arastirma Hospital

location_facility: Tokitokai Tokito Clinic Coloproctology Center

location_facility: Inonu Universitesi Turgut Ozal Tip Merkezi, Ic Hastaliklari

location_facility: Universitatsklinikum Schleswig-Holstein - Kiel

location_facility: The first affiliated hospital of suzhou University

location_facility: MNCE'City Clinical Hospital №2 named after prof. O.O. Shalimov' of the Kharkiv City Council

location_facility: Wexner Medical Center at the Ohio State University

location_facility: The second Xiangya Hospital of Central South University

location_facility: University Clinical Centre of the Republic of Srpska

location_facility: Clinical Hospital Center Bezanijska Kosa

location_facility: Harvard Medical School-Beth Israel Deaconess Medical Center

location_facility: Gastroenterology Consultants of Southwest Virginia

location_facility: O.O.Bogomolets National Medical University, Kyiv City Clinical Hospital #18,

location_facility: Synexus Polska Sp. z o.o. Oddzial w Gdansku

location_facility: Toronto Digestive Disease Associates Inc

location_facility: CHA Bundang Medical Center, CHA University

location_facility: Synexus Polska Sp. z o.o. Oddzial w Warszawie

location_facility: The Hospital of Hyogo College of Medicine

location_facility: Synexus Polska Sp. z.o.o. Oddzial w Poznaniu

location_facility: Vilnius University Hospital Santaros Klinikos, Public Institution

location_facility: GBUZ of Moscow Region City Clinical Hospital #3

location_facility: King Abdullah Medical City in Holy Capital

location_facility: Gastroenterologie und Hepatologie am Johannisplatz

location_facility: Synexus Polska Sp. z o.o. Oddzial we Wroclawiu

location_facility: Gastromed Spotka Z Ograniczona Odpowiedzialnoscia Sp. K.

location_facility: University Hospital Kyoto Perfectural University of Medicine

location_facility: Wojewodzki Szpital Specjalistyczny w Olsztynie

location_facility: Zhangzhou Municipal Hospital of Fujian Province

location_facility: NZOZ Vivamed Zespol Lekarzy Specjalistow

location_facility: Ltd Central University Clinic by Academician N.Kipshidze

location_facility: Sir Run Run Shaw Hospital, Zhejiang University School of Medicine

location_facility: The 1st affiliated hospital of Anhui Medical University

location_facility: Kyiv Railway Clinical Hospital #2 Of Branch 'Health Center' Of The Company 'Ukrainian Railway'

location_facility: Istanbul Medeniyet University Goztepe Training and Research Hospital

location_facility: Universitaetsklinikum Charite, Campus Virchow Klinikum

location_facility: University of Alberta- Ziedler Ledcor Centre

location_facility: The Military General Hospital of Beijing PLA

location_facility: Synexus Polska Sp. z o.o. Oddzial w Czestochowie

location_facility: First Affiliated Hospital of Kunming Medical Unversity

location_facility: ARS MEDICA Rybak Maria, Rybak Zbigniew, s.c.

location_facility: Federal State Budgetary Institution 'Scientific Research In

location_facility: Gastroenterology Research of America, LLC

location_facility: Elite Research Network - Nature Coast Clinical Research, LLC

location_facility: Martini-Klinik am Universitätsklinikum Hamburg-Eppendorf Urologie

location_facility: Synexus Polska Sp. z o.o. Oddzial w Katowicach

location_facility: Centrum Diagnostyczno - Lecznicze Barska sp. z o.o. Szpital Specjalistyczny Barska

location_facility: Gruppo Ospedaliero San Donato - Istituto di Ricovero e Cura

location_facility: National Hospital Organization Kochi National Hospital

location_facility: Niigata University Medical & Dental Hospital

location_facility: Centre Hospitalier Universitaire (CHU) de Caen

location_facility: Corporacion para Estudios en Salud Clinica CES - Gastroenterology

location_facility: Universitätsklinikum Salzburg - Landeskrankenhaus

location_facility: Instituto Goiano de Gastroenterologia e Endoscopia Digestiva

location_facility: LLC Treatment and Diagnostic Center Adonis Plus

location_facility: Martin-Luther-Universitaet Halle-Wittenberg - Universitaetsk

location_facility: NUZ 'Railway Clinical Hospital on Samara station of LLC 'Russian Railways'

location_facility: Harmony Medical Research Institute, Inc.

location_facility: Gastroenterologische Praxis Balsiger und Seibold

location_facility: Huron Gastroenterology Associates Center for Digestive Care

location_facility: Centro Hospitalar e Universitário de Coimbra, EPE

location_facility: Azienda Ospedaliero Universitaria di Cagliari - Policlinico Duilio Casula di Monserrato

location_facility: Republican Research Centre of Radiation Medicine and Human E

location_facility: Nottingham University Hospitals NHS Trust

location_facility: Kitasato University Kitasato Institute Hospital

location_facility: National Hospital Organization Higashi Ohmi General Medical Center

status_simplified: Ongoing


status: Active, not recruiting

lead_sponsor: EMD Serono Research & Development Institute, Inc.

location_country:
Peru
Greece
Romania
Belgium
Australia
Russian Federation
Denmark
Taiwan
Ukraine
Croatia
France
Japan
Lithuania
Poland
Slovakia
Thailand
Canada
Korea, Republic of
Turkey
Colombia
South Africa
Chile
Netherlands
Bulgaria
Singapore
Hungary
Ireland
China
Portugal
Germany
United States
United Kingdom
Italy
Brazil
Serbia
Lebanon
Cyprus
Czechia
Israel
New Zealand
Spain
Estonia

location_facility: Hospital Regional Universitario de Malaga

location_facility: Complejo Hospitalario Universitario de Santiago

location_facility: Centrum Onkologii-Instytut im. M. Sklodowskiej Curie

location_facility: IPS IMAT- Instituto Medico de Alta Tecnologia - Oncomedica S.A.

location_facility: University Hospital Centre "Sestre Milosrdnice"

location_facility: RBIH "Kursk regional clinical oncology dispensary" of Kursk Region Healthcare Committee

location_facility: CRIO - Centro Regional Integrado de Oncologia

location_facility: The Catholic University of Korea, Yeouido St. Mary's Hospital

location_facility: Borsod-Abauj-Zemplen Megyei Kozponti Korhaz es Egyetemi Oktatokorhaz

location_facility: Centrum Terapii Wspolczesnej J.M. Jasnorzewska sp. komandytowo-akcyjna

location_facility: Hospital Erasto Gaertner - Liga Paranaense de Combate ao Câncer

location_facility: Nemocnica s poliklinikou Sv. Jakuba, n.o. Bardejov

location_facility: CI Chernivtsi RC Oncological Dispensary Bukovinian SMU Ch of Oncology and Radiology

location_facility: FSBHI Clinical research institute of phthisiopulmonology

location_facility: Spitalul Judetean de Urgenta "Dr. Constantin Opris" Baia Mare

location_facility: Treatment-Diagnostic Center of Private Enterprise of PPC Atsynus

location_facility: Centro Hospitalar de Lisboa Norte, E.P.E. - Hospital Pulido Valente

location_facility: ICESP - Instituto do Câncer do Estado de São Paulo Octavio Frias de Oliveira

location_facility: Bakirkoy Dr. Sadi Konuk Teaching and Research Hospital

location_facility: Fundação Faculdade Regional de Medicina de São José do Rio Preto

location_facility: SzSzB Megyei Korhazak es Egyetemi Oktatokorhaz

location_facility: SBIH "Samara Regional Clinical Oncological Dispensary"

location_facility: University Clinic for Pulmonary Diseases

location_facility: Istanbul University Cerrahpasa Medical Faculty

location_facility: Szpital Kliniczny Przemienienia Panskiego Uniwersytetu Medycznego im. Karola Marcinkowskiego

location_facility: S.C Centrul de Oncologie Sf. Nectarie S.R.L

location_facility: SP Zespol Gruzlicy i Chorob Pluc w Olsztynie

location_facility: Gallipoli Medical Research Foundation Ltd

location_facility: CEPHO - Centro de Estudos e Pesquisas em Hematologia e Oncologia

location_facility: Fondazione Poliambulanza Istituto Ospedaliero

location_facility: CHU de Strasbourg - Nouvel Hôpital Civil

location_facility: Clinical Center Nis, Pulmonary Diseases Clinic

location_facility: Hadassah University Hospital - Ein Kerem

location_facility: SBHI of Kaluga Region "Kaluga regional clinical oncology dispensary"

location_facility: Centro de Investigaciones Clinicas Viña del Mar

location_facility: Lviv State Oncological Regional Treatment and Diagnostic Center

location_facility: The Catholic University of Korea, Seoul St. Mary's Hospital

location_facility: RBIH "Ivanovo Regional Oncological Dispensary"

location_facility: Centre Hospitalier Intercommunal de Créteil

location_facility: ICO Girona - Hospital Universitari de Girona Dr. Josep Trueta

location_facility: IMV-Pesquisa Cardiologica Sociedade Simples - HMD - COR

location_facility: Baskent University Adana Application and Research Center

location_facility: Kemerovo SPI Regional Clinical Oncology Dispensary

location_facility: Yonsei University Wonju Severance Christian Hospital

location_facility: Csongrad Megyei Mellkasi Betegsegek Szakkorhaza

location_facility: American University of Beirut Medical Center

location_facility: Complejo Hospitalario Universitario de Vigo

location_facility: SBIH of Arkhangelsk region "Arkhangelsk Clinical Oncological Dispensary"

location_facility: CI Transcarpathian Cl Onc Center Dep of Surgery#1 SHEI Ivano-Frankivsk NMU

location_facility: Communal Non-profit Enterprise Regional Center of Oncology

location_facility: The Catholic University of Korea, St. Vincent's Hospital

location_facility: Krajska zdravotni, a.s. - Masarykova nemocnice v Usti nad Labem, o.z.

location_facility: CEPON - Centro de Pesquisas Oncológicas de Santa Catarina

location_facility: Centro Hospitalar do Porto, E.P.E. - Hospital de Santo António

location_facility: Hospital General Universitario Gregorio Marañon

location_facility: CI Dnipropetrovsk CMCH #4 of Dnipropetrovsk RC Dept of Chemotherapy SI Dnipropetrovsk MA of MOHU

location_facility: Okmeydani Research and Training Hospital

location_facility: Instituto Português de Oncologia do Porto Francisco Gentil, EPE

location_facility: Institute of Biomedical Research and Innovation Hospital

location_facility: Clinique Victor Hugo - Centre Jean Bernard

location_facility: Kobe City Hospital Organization Kobe City Medical Center General Hospital

location_facility: Instituto Nacional de Enfermedades Neoplásicas

location_facility: SBIH of Stavropol territory "Pyatigorsk Oncological Dispensary"

location_facility: Hospital de Câncer de Barretos - Fundação Pio XII

location_facility: SAIH "Republican Clinical Oncological Dispensary of the Ministry of Healthcare of Republic Tatarstan

location_facility: CHA Bundang Medical Center, CHA University

location_facility: Hospital of Lithuanian University of Health Sciences Kaunas Clinics

location_facility: Univerzitna nemocnica Bratislava, Nemocnica Ruzinov

location_facility: Hospital Professor Doutor Fernando Fonseca, E.P.E.

location_facility: Institutul Oncologic "Prof. Dr. Ion Chiricuta" Cluj Napoca

location_facility: FSBSI "Russian Oncological Scientific Center n.a. N.N. Blokhin"

location_facility: Seoul National University Bundang Hospital

location_facility: Fundación Oftalmológica de Santander - FOSCAL

location_facility: Treatment-Prevention Institution Volyn Regional Oncological Dispensary

location_facility: Hammoud Hospital University Medical Center

location_facility: Adana Numune Training and Research Hospital

location_facility: Harbin Medical University Cancer Hospital

location_facility: Spitalul Clinic Judetean de Urgenta "Sf. Apostol Andrei" Constanta

location_facility: Kyungpook National University Chilgok Hospital

location_facility: Centro Hospitalar de Entre o Douro e Vouga, E.P.E - Hospital de São Sebastião

location_facility: SI S.P.Grygoriev Institute of Medical Radiology of NAMSU

location_facility: Centro Hospitalar de Lisboa Central, E.P.E. - Hospital de Santo António dos Capuchos

location_facility: Chelyabinsk Regional Oncology Dispensary

location_facility: University of Pretoria Oncology Department

location_facility: University General Hospital of Heraklion

location_facility: RCI Sumy Regional Clinical Oncological Dispensary

location_facility: SBHI "Krasnoyarsk Regional Oncology Dispensary n.a. A.I. Kryzhanovsky"

location_facility: Spitalul Judetean de Urgenta "Sf. Ioan cel Nou" Suceava

location_facility: CCCH City Oncological Center SHEI Uzhgorod NU

location_facility: Azienda Ospedaliero Universitaria di Parma

location_facility: Seconda Università degli Studi di Napoli

location_facility: General Hospital of Athens of Chest Diseases "SOTIRIA"

location_facility: Wojewódzkie Wielospecjalistyczne Centrum Onkologii i Traumatologii im. M. Kopernika w Łodzi

location_facility: Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital

location_facility: Mazowieckie Centrum Leczenia Chorob Pluc i Gruzlicy

location_facility: Hospital Universitario Mutua de Terrassa

location_facility: IBCC - Instituto Brasileiro de Controle do Câncer

location_facility: Kartal Lutfi Kirdar Research and Training Hospital

location_facility: Azienda Ospedaliero Universitaria Pisana

location_facility: SBIH "Leningrad Regional Oncological Dispensary"

location_facility: FBI "Scientific Research Institute of Oncology n. a. N. N. Petrov"

location_facility: Centro Hospitalar e Universitário de Coimbra, E.P.E (CHC)

location_facility: Azienda Ospedaliero Universitaria San Martino

location_facility: Institute of Oncology and Radiology of Serbia

location_facility: Spitalul Clinic Municipal "Dr. Gavril Curteanu" Oradea

location_facility: Murmansk Regional Clinical Hospital named after Bayandin

location_facility: CEBROM - Centro Brasileiro de Radioterapia, Oncologia e Mastologia

location_facility: SBHI of Novosibirsk region "Novosibirsk Regional Oncological Dispensary"

location_facility: SBIH "Oncological Dispensary # 2" of the MoH of Krasnodar territory

location_facility: General Oncology Hospital of Kifissia " Agioi Anargyroi"

location_facility: BHI of Omsk region "Clinical Oncology Dispensary"

location_facility: SBIH of Yaroslavl region "Regional Clinical Oncological Hospital"

location_facility: Izerskie Centrum Pulmonologii i Chemioterapii "IZER-MED" Spolka z o.o.

location_facility: Spitalul Militar de Urgenta "Dr.Constantin Papilian"Cluj -Napoca

location_facility: CI Kryvyi Rih Oncological Dispensary of DRC

location_facility: Groupe Hospitalier Sud - Hôpital Haut-Lévêque

location_facility: Centro Hospitalar Vila Nova de Gaia/Espinho, E.P.E

location_facility: Institute for Pulmonary Diseases of Vojvodina

location_facility: Institutul Oncologic "Prof. Dr. Al. Trestioreanu"

location_facility: Vinnytsia Regional Clinical Oncological Dispensary

title: A Phase III, Open-label, Multicenter Trial of Avelumab (MSB0010718C) Versus Platinum-based Doublet as a First-line Treatment of Recurrent or Stage IV PD-L1+NSCLC

summary: The purpose of this study is to demonstrate superiority with regard to Overall Survival (OS) or Progression Free Survival (PFS) of avelumab versus platinum-based doublet, based on an Independent Review Committee assessment, in Non-small cell lung cancer (NSCLC) subjects with Programmed death ligand 1+ (PD-L1+) tumors


title: Multiple Patient Program to Ensure Access to LCZ696 Treatment to Patients Diagnosed With Heart Failure With Reduced Ejection Fraction (HF-rEF)

summary: Novartis has set up this global Multiple Patient Program (MPP) treatment plan to provide access to life-saving treatment with LCZ696 for patients that were not previously exposed to LCZ696 but have no other option to receive LCZ696 in their country prior to market authorization OR commercial availability, based on local regulatory and legal requirements.

status: No longer available

study_type: Expanded Access

lead_sponsor: Novartis Pharmaceuticals

location_country:
Austria
Brazil
United Arab Emirates
Switzerland
Lebanon
Philippines
Germany
Cyprus
Croatia
France
Greece
Panama
Malta
Ireland
Australia
Spain
United States
Slovenia

status_simplified: Unknown


lead_sponsor: Arena Pharmaceuticals

location_country:
Romania
Australia
Belgium
Russian Federation
Denmark
Ukraine
India
Spain
Croatia
France
Japan
Lithuania
Poland
Slovakia
Thailand
Argentina
Moldova, Republic of
Canada
Korea, Republic of
Turkey
Colombia
South Africa
Chile
Switzerland
Netherlands
Bulgaria
Hungary
Portugal
Germany
United States
United Kingdom
Italy
Austria
Serbia
Lebanon
Mexico
Czechia
Israel
Georgia
Belarus
Estonia

acronym: ELEVATE UC 12

location_facility: Department of Propaedeutics of Internal Medicine Ivano-Frankivsk National Medical University

location_facility: Kyiv CCH #18 Dept of Proctology O. O. Bogomolets NMU

location_facility: Tokushukai Kishiwada Tokushukai Hospital

location_facility: Groupement Hospitalier Sud - Hôpital Bicêtre

location_facility: Topolowa Medicenter Mrozek & Wspolnicy Spolka Jawna

location_facility: EMC INSTYTUT MEDYCZNY SA, EuroMediCare Szpital Specjalistyczny z Przychodnia - Dzial Farmacji

location_facility: Dept of Gastroenterology, Szent Gyorgy Hospital

location_facility: Medical College of Wisconsin Clinical Trials Office

location_facility: Shiga University of Medical Science Hospital

location_facility: Kitasato University Kitasato Institute Hospital

location_facility: Timofei Mosneaga Republican Clinical Hospital, Department of Gastroenterology

location_facility: Texas Digestive Disease Consultants - San Marcos

location_facility: Great Lakes Medical Research, LLC - Mentor

location_facility: Vilnius University Hospital Santaros Clinics, Center of Hepatology, Gastroenterology and Dietology

location_facility: Republican Panevezys Hospital, Department of Gastroenterology

location_facility: CNE Prof. O.O. Shalimov Kharkiv City Clinical Hospital #2 of KCC

location_facility: Centro Hospitalar de Vila Nova de Gaia/Espinho, E.P.E

location_facility: Spitalul Clinic Judetean de Urgenta Cluj Napoca

location_facility: Clinica farallones centro de investigaciones clinicas CIC

location_facility: Communal Non-Commercial Enterprise City Clinical Hospital #13 of Kharkiv City Council

location_facility: Children's Center for Digestive Health Care, LLC

location_facility: Charité Universitätsmedizin Berlin - Campus Charité Mitte

location_facility: SBIH of Nizhniy Novgorod region "Nizhniy Novgorod Regional Clinical Hospital n.a. N.A. Semashko"

location_facility: SRI of Invalid Rehabilitation (EST Complex) of Vinnytsia M.I.Pyrogov NMU MOHU

location_facility: Spitalul Clinic Judetean de Urgenta Craiova

location_facility: Private Educational Institution of Higher Education "Medical University "REAVIZ"

location_facility: Karkonoskie Centrum Badan Klinicznych Lexmedica

location_facility: State Budgetary Healthcare Institution "Penza Region Clinical Hospital n.a. N.N. Burdenko"

location_facility: Clinica de la Mujer Centro de Investigaciones

location_facility: Medical Clinical Investigational Center of Medical Center Health Clinic LLC

location_facility: Iwate Medical University Uchimaru Medical Center

location_facility: M.I. Pyrogov VRCH Dept of Gastroenterology M.I. Pyrogov VNMU

location_facility: The Catholic University of Korea St. Vincent's Hospital

location_facility: Hospital da Senhora da Oliveira Guimarães

location_facility: SAIH "Kemerovo Regional Clinical Hospital"

location_facility: Clinic for Internal Medicine I, University hospital Schleswig-Holstein, Campus Kiel

location_facility: UMHATEM "N.I.Pirogov" EAD, Gastroenterology Department/Clinical Research center

location_facility: Azienda Ospedaliera Universitaria Careggi

location_facility: Debreceni Egyetem Klinikai Kozpont Belgyogyaszati Klinika -Gasztroenterologia

location_facility: Kremenchuk first city hospital n.a. O.T. Bohaievskyi

location_facility: Hadassah University Hospital - Ein Kerem

location_facility: Allmedica Badania Kliniczne Sp. z o.o. Sp.k.

location_facility: Semmelweis Egyetem, II.sz. Belgyogyaszati Klinika

location_facility: Stavropol Regional Clinical Diagnostic Centre

location_facility: CHU Clermont Ferrand - Hôpital d'Estaing

location_facility: Washington University School of Medicine

location_facility: KH der Barmherzigen Brüder Linz, Interne Abteilung

location_facility: General Hospital "Dr. Tomislav Bardek" Koprivnica

location_facility: Centralny Szpital Kliniczny MSW w Warszawie

location_facility: Communal Non-commercial Enterprise of Kharkiv Regional Council Regional Clinical Hospital

location_facility: Government Medical College and Super Speciality Hospital

location_facility: Gastromed Kralisz, Romatowski, Stachurska sp.j

location_facility: Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (Presidio Spedali Civili)

location_facility: LTD Israeli-Georgian medical research clinic Helsicore

location_facility: Twoja Przychodnia-Szczecinskie Centrum Medyczne

location_facility: Instituto de Investigaciones Clínicas Quilmes SRL

location_facility: Azienda Ospedaliera Universitaria Policlinico Sant'Orsola Malpighi

location_facility: Yonsei University Wonju Severance Christian Hospital

location_facility: American University of Beirut Medical Center

location_facility: Dr. Peter Bossuyt - GI Clinical Research Center

location_facility: RTL SM SRL, Institutia Medico- Sanitara Publica Spitalul Clinic, Sectia Proctologie

location_facility: Centro Hospitalar e Universitário de Coimbra Serviço Gastrenterologia

location_facility: Texas Digestive Disease Consultants - Dallas

location_facility: Japan Community Health care Organization Osaka Hospital

location_facility: I.I.Mechnykov Dnipropetrovsk Regional Clinical Hospital

location_facility: ACIBADEM CITY CLINIC TOKUDA HOSPITAL EAD,Clinical Research Center

location_facility: Aalborg University Hospital, department of medical gastroenterology

location_facility: A.O. Ordine Mauriziano di Torino - P.O. Ospedale Umberto I

location_facility: Clinical Center " Dr Dragisa Misovic Dedinje"

location_facility: Bekes Megyei Kozpont Korhaz Dr Rethy Pal Tagkorhaz, 4. Belgyogyaszat es 2. Gasztroenterologia

location_facility: Malkhaz Katsiashvili Multiprofile Emergency Medicine Center

location_facility: Fakultna nemocnica s poliklinikou F.D. Roosevelta

location_facility: Guy's and Saint Thomas NHS Foundation Trust

location_facility: Fundación Respirar- Centro Médico Dra. De Salvo

location_facility: Acibadem City Clinic University Hospital EOOD

location_facility: Republican Clinical Hospital, ARENSIA Exploratory Medicine

location_facility: Hospital San Juan de Dios Fundacion Cardiomet-Cequin

location_facility: Berner IBD study group c/o Gastroenterologische Praxis Balsiger, Seibold &Partner

location_facility: LTD Acad. F. Todua Medical Centre, LTD. Research Institution of Clinical Medicine

location_facility: LTD Central University Clinic After Academic N. Kipshidze

location_facility: JSC Infectious Diseases, AIDS and Clinical Immunology Research Center

location_facility: Saint George Hospital University Medical Center

location_facility: Fondazione Policlinico Universitario Agostino Gemelli IRCCS - CEMAD

location_facility: Hiroshima City Hiroshima Citizens Hospital

location_facility: Zuyderland Medisch Centrum - Sittard-Geleen

location_facility: FSBI of higher Education "First Saint Petersburg State Medical University n.a. I.P.Pavlov

location_facility: UAB "Inlita", Santaros Clinical Trials Centre

location_facility: Vitebsk Regional Clinical Specialized Center

location_facility: Azienda Ospedaliero Universitaria Mater Domini

location_facility: Kyungpook National University Chilgok Hospital

location_facility: Hôpital Rangueil Service Gastro-entérologie et pancreatologie

location_facility: The University of Texas at Austin Dell Medical School

location_facility: Hospital Universitario de Gran Canaria Dr. Negrin

location_facility: Centro de Investigacion Medico Biologica y Terapia Avanzada s.c.

location_facility: Communal Noncommercial Enterprise Ye.Ye. Karabelesh Kherson City Clinical Hospital of Kherson City

location_facility: S.C Delta Health Care S.R.L, Ponderas Academic Hospital

location_facility: Municipal non-profit enterprise Regional Clinical Hospital of Ivano-Frankivsk Regional Council, Ga

location_facility: Inselspital, Gaby Saner, Gastroenterologie, Bauchzentrum

location_facility: LLC "Multidisciplinary Medical Clinic "Anthurium"

location_facility: University Hospital Antwerp Gastroenterology and Hepatology Department

location_facility: Kocaeli University Research and Training Hospital

location_facility: Medical center "Nov Rehabilitatsionen Tsentar" EOOD

location_facility: Marshall University Department of Clinical Research

location_facility: Irkutsk State Medical Academy of Continuing Education

location_facility: Severance Hospital, Yonsei University Health System

location_facility: Digestive Health Specialists of the Southeast

location_facility: SZTE AOK I.st dept. of Internal Medicine.

location_facility: Odesa regional clinical hospital, regional center of gastroenterology, surgical department

location_facility: Federal state Budgetary Educational Institution of Higher Education "North-Western Medical University"

location_facility: SPb SBIH "City Hospital # 40 of Kurortnyi region"

location_facility: SUBARU Health Insurance Society Ota Memorial Hospital

location_facility: Postgraduate department of Medicine, GSVM Medical college

location_facility: Hospital General Universitario de Alicante

location_facility: Communal Non-Commercial Enterprise Lviv Clinical Hospital of Emergency Medical Care

location_facility: Diagnostic-Consultative Center I - Sliven, EOOD

location_facility: Great Lakes Medical Research, LLC - Harrisburg

location_facility: A. Novak Transcarpathian Regional Clinical Hospital

location_facility: Institution "Gomel Regional Clinical Hospital"

location_facility: Centrum Dentystyczno-Lekarskie Promedica Joanna Markiewicz

location_facility: Atlanta Center for Gastroenterology, P.C.

location_facility: Diagnostic Consultation Center CONVEX EOOD

ipd_sharing: No

title: A Phase 3, Randomized, Double-Blind, Placebo-Controlled, 12-Week Study to Assess the Efficacy and Safety of Etrasimod in Subjects With Moderately to Severely Active Ulcerative Colitis

summary: The purpose of this study is to assess the efficacy of etrasimod on clinical remission in participants with moderately to severely active ulcerative colitis (UC).


title: VERDICT: In actiVE Ulcerative Colitis, a RanDomIzed Controlled Trial for Determination of the Optimal Treatment Target

acronym: VERDICT

summary:
Disease activity and response to therapy in ulcerative colitis (UC) can be assessed by a range of endpoints including symptoms, endoscopic mucosal activity, histological disease activity, and biomarkers. This study aims to determine the optimal treatment target, which is a research priority for the management of UC both to inform clinical practice and to help inform regulatory endpoints and targets for drug development.

Participants with active UC will be randomized in a 2:3:5 ratio to 1 of 3 groups, each with a different treatment target. Treatment targets will be defined as:

Group 1: corticosteroid-free symptomatic remission
Group 2: corticosteroid-free endoscopic + symptomatic remission
Group 3: corticosteroid-free histological + endoscopic + symptomatic remission

ipd_sharing: Undecided

lead_sponsor: Alimentiv Inc.

location_country:
United States
Netherlands
France
Belgium
Canada
United Kingdom

location_facility: London Health Sciences Centre - University Campus

location_facility: Toronto Immune and Digestive Health Institute (TIDHI)

location_facility: Amsterdam UMC - Academisch Medisch Centrum

location_facility: Icahn School of Medicine at Mt Sinai Hospital

location_facility: Asheville Gastroenterology Associates, PA

location_facility: UZ Leuven - University Hospital Gasthuisberg

location_facility: Huron Gastroenterology Associates - Center for Digestive Care

location_facility: CHU de Bordeaux - Hopital Haut Leveque - Groupe Hospitalier Sud

intervention_type: Biological


intervention_type: Other

location_country:
Italy
Brazil
United States
Switzerland
Spain
Germany
France
Czechia
Greece
Israel
Japan
Australia
Russian Federation
China
Canada
United Kingdom
Korea, Republic of
Taiwan

acronym: VIALE-T

location_facility: Tulane Medical Center - New Orleans /ID# 239590

location_facility: Fujian Medical University Union Hospital /ID# 215555

location_facility: Guangdong Provincial People's Hospital /ID# 218666

location_facility: Medizinische Hochschule Hannover /ID# 214243

location_facility: Hospital de Clinicas de Porto Alegre /ID# 215042

location_facility: Union Hospital Tongji Medical College Huazhong University of Science and Technol /ID# 238373

location_facility: University of California, Los Angeles /ID# 218199

location_facility: Ruijin Hospital, Shanghai Jiaotong University School of Medicine /ID# 239317

location_facility: Hospital Universitario Virgen del Rocio /ID# 215463

location_facility: Ann & Robert H Lurie Children's Hospital of Chicago /ID# 215840

location_facility: The First Affiliated Hospital, Zhejiang University School of Medicine /ID# 215550

location_facility: Children's Hospital of Philadelphia - Main /ID# 215410

location_facility: CIUSSS de l'est de l'Ile-de-Montreal - Hopital Maisonneuve-Rosemont /ID# 214591

location_facility: The Affiliated Hospital of Xuzhou Medical University /ID# 239098

location_facility: ASST Spedali civili di Brescia /ID# 215997

location_facility: Memorial Sloan Kettering Cancer Center-Koch Center /ID# 240680

location_facility: Indiana Blood & Marrow Transpl /ID# 215842

location_facility: University of Arkansas for Medical Sciences /ID# 239804

location_facility: Princess Margaret Cancer Centre /ID# 215344

location_facility: Almazov National Medical Research Centre /ID# 214357

location_facility: University General Hospital of Patras /ID# 238811

location_facility: Roswell Park Comprehensive Cancer Center /ID# 217857

location_facility: The Royal Marsden NHS Foundation Trust /ID# 215124

location_facility: Colorado Blood Cancer Institute /ID# 215980

location_facility: Hospital Universitario La Paz /ID# 218103

location_facility: Univ of Wisconsin Hosp/Clinics /ID# 216096

location_facility: Fondazione Policlinico Universitario Agostino Gemelli IRCCS-Università Cattolica /ID# 214910

location_facility: Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital /ID# 215939

location_facility: Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sc /ID# 215546

location_facility: Peking University People's Hospital /ID# 215551

location_facility: Tel Aviv Sourasky Medical Center /ID# 214508

location_facility: Hokkaido University Hospital /ID# 215937

location_facility: Jichi Medical University Saitama Medical Center /ID# 216092

location_facility: Hospital Universitario Ramon y Cajal /ID# 218102

location_facility: Rogachev Nat Med Research Ctr for Pediatric Hematology, Onc /ID# 216538

location_facility: Ustav hematologie a krevni transfuze /ID# 215133

location_facility: Loyola University Medical Ctr /ID# 215617

location_facility: University of Mississippi Medical Center /ID# 239343

location_facility: Royal Victoria Hospital / McGill University Health Centre /ID# 215253

location_facility: Tongji Hospital Tongji Medical College Huazhong University of Science and Techno /ID# 215552

location_facility: Universitaetsklinikum Wuerzburg /ID# 215212

location_facility: General Hospital of Athens Evangelismos /ID# 238810

location_facility: Jichi Medical University Hospital /ID# 216091

location_facility: St Jude Children's Research Hospital /ID# 214074

location_facility: University College London Hospitals NHS Foundation Trust /ID# 215662

location_facility: Hadassah Medical Center-Hebrew University /ID# 218697

location_facility: Vancouver Coastal Health Research Institute (VCHRI) /ID# 215363

location_facility: The First Affiliated Hospital of Soochow University /ID# 216605

location_facility: Universitaetsklinikum Muenster /ID# 215213

location_facility: The First Affiliated Hospital of Nanchang University /ID# 239168

location_facility: Penn State Hershey Medical Ctr /ID# 217120

location_facility: Texas Oncology- Baylor Charles A. Sammons Cancer Center /ID# 213735

location_facility: The Chaim Sheba Medical Center /ID# 214305

location_facility: Hospital Santa Creu i Sant Pau /ID# 240397

location_facility: Fakultni nemocnice Hradec Kralove /ID# 214814

location_facility: Kobe City Medical Center General Hospital /ID# 215388

location_facility: Zhongda Hospital Southeast University /ID# 218926

location_facility: University of Oklahoma, Stephenson Cancer Center /ID# 215611

location_facility: The Catholic University of Korea, Seoul St. Mary's Hospital /ID# 214892

location_facility: Fred Hutchinson Cancer Research Center /ID# 214436

location_facility: Texas Oncology - Medical City Dallas /ID# 216720

location_facility: Imperial College Healthcare NHS Trust /ID# 215665

location_facility: Ochsner Clinic Foundation-New Orleans /ID# 213834

location_facility: CHU de Nantes, Hotel Dieu -HME /ID# 214060

location_facility: Academician I.P. Pavlov First St. Petersburg State Medical University /ID# 214609

location_facility: Hospital Clinico Universitario de Valencia /ID# 215106

location_facility: University Hospitals Birmingham NHS Foundation Trust /ID# 215120

location_facility: Tangdu Hospital of The Fourth Military Medical University, PLA /ID# 216282

location_facility: Chinese PLA General Hospital /ID# 216287

location_facility: Saint Louis University Cancer Center /ID# 239633

location_facility: Universitaetsklinik Heidelberg /ID# 216623

location_facility: University Hospitals - Seidman Cancer Center /ID# 239260

location_facility: Ottawa Hospital Research Institute /ID# 238820

location_facility: Weill Cornell Medical College /ID# 214887

location_facility: Greenebaum Comprehensive Cancer Center - UM /ID# 213855

location_facility: University General Hospital Attikon /ID# 238812

location_facility: Japanese Red Cross Aichi Medical Center Nagoya Daiichi Hospital /ID# 215679

location_facility: Kirov Research Institute of Hematology and Blood Transfusion of FMBA /ID# 216591

location_facility: Seoul National University Hospital /ID# 214891

location_facility: Zhujiang Hospital of Southern Medical University /ID# 216333

location_facility: Hyogo College of Medicine College Hospital /Id# 215389

location_facility: Xiangya Hospital Central South University /ID# 219025

location_facility: Universitaetsklinikum Halle (Saale) /ID# 239585

location_facility: AdventHealth Medical Group Blood & Marrow Transplant at Orlando /ID# 213985

location_facility: A.O.U. Citta della Salute e della Scienza di Torino /ID# 216148

location_facility: UCHSC Anschultz Cancer Pavilion /ID# 215618

location_facility: Hospital General Universitario Gregorio Maranon /ID# 215107

location_facility: Montefiore Medical Center - Moses Campus /ID# 241669

location_facility: Schneider Children's Medical Center /ID# 224326

location_facility: TriStar Centennial Medical Center /ID# 218750

location_facility: Hospital Clinic de Barcelona /ID# 215108

location_facility: Perelman Center for Advanced Medicine - /ID# 214518

location_facility: NHS Greater Glasgow and Clyde /ID# 215663

location_facility: The University of Chicago Medical Center /ID# 215616

location_facility: Columbia University Medical Center /ID# 240875

location_facility: Taipei Veterans General Hosp /ID# 239289

location_facility: Beth Israel Deaconess Medical Center /ID# 221181

location_facility: Oregon Health & Science University /ID# 215874

location_facility: National Taiwan University Hospital /ID# 215245

location_facility: CHRU Lille - Hopital Claude Huriez /ID# 217916

location_facility: University of North Carolina /ID# 215814

location_facility: Taichung Veterans General Hospital /ID# 239288

location_facility: King's College Hospital NHS Foundation Trusts /ID# 215338

location_facility: Massachusetts General Hospital /ID# 215765

location_facility: AP-HP - Hopital Saint-Antoine /ID# 216957

location_facility: Chu de Nice-Hopital L'Archet Ii /Id# 214056

location_facility: Linkou Chang Gung Memorial Ho /ID# 215319

location_facility: Karmanos Cancer Institute - Dresner Clinic /ID# 214581

location_facility: Universitaetsklinikum Carl Gustav Carus an der TU Dresden /ID# 214244

location_facility: Nanfang Hospital of Southern Medical University /ID# 215553

location_facility: CHU Bordeaux - Hopital Haut Lévêque /ID# 214055

location_facility: Osaka City University Hospital /ID# 215227

location_facility: Kaohsiung Medical University Chung-Ho Memorial Hospital /ID# 215197

location_facility: China Medical University Hospital /ID# 215198

title: A Randomized, Open Label Phase 3 Study Evaluating Safety and Efficacy of Venetoclax in Combination With Azacitidine After Allogeneic Stem Cell Transplantation in Subjects With Acute Myeloid Leukemia (AML) (VIALE-T)

summary:
The main objective of this study is to evaluate the efficacy of venetoclax in combination with azacitidine to improve Relapse Free Survival (RFS) in Acute Myeloid Leukemia (AML) participants compared to Best Supportive Care (BSC) when given as maintenance therapy following allogeneic stem cell transplantation (SCT).

This study will have 2 parts: Part 1 (Dose Confirmation), which may include participants who are greater than or equal to 18 years old; Part 2 (Randomization) which may include participants who are greater than or equal to 12 years old. During Part 1, recommended Phase 3 dose of venetoclax in combination with azacitidine will be determined and during Part 2, the efficacy and safety of venetoclax with azacitidine (Part 2 Arm A) will be compared with BSC (Part 2 Arm B).


title: A Phase 1/2 Study on the Safety of Rovalpituzumab Tesirine Administered in Combination With Nivolumab or Nivolumab and Ipilimumab for Adults With Extensive-Stage Small Cell Lung Cancer

summary: The purpose of this study is to assess the safety and efficacy of rovalpituzumab tesirine administered in combination with nivolumab or nivolumab and ipilimumab in participants with extensive-stage small cell lung cancer (SCLC).

status: Terminated

design_allocation: Non-Randomized

location_country:
Italy
United States
France
Spain
Germany

location_facility: University Cancer & Blood Cent /ID# 161028

location_facility: Oregon Health and Science University /ID# 161029

location_facility: Lungenfachklinik Immenhausen /ID# 165181

location_facility: Medical University of South Carolina /ID# 161007

location_facility: Hospital Universitario Fundacion Jimenez Diaz /ID# 165164

location_facility: Rutgers Cancer Institute of NJ /ID# 161032

location_facility: The University of Kansas Clini /ID# 162915

location_facility: Clinica Universitar de Navarra - Pamplona /ID# 165165

location_facility: University of Wisconsin Clinic /ID# 161013

location_facility: CHU de Besancon - Jean Minjoz /ID# 165173

location_facility: Centro di Riferimento Oncologi /ID# 165174

location_facility: Azienda Ospedaliero Universitaria Policlinico Vittorio Emanuele /ID# 165178

location_facility: Duke University Medical Center /ID# 161009

location_facility: CHRU de Brest - Hospital Morva /ID# 165170

location_facility: Istituto Europeo di Oncologia /ID# 165175

location_facility: Memorial Sloan Kettering Cancer Center /ID# 161010

location_facility: Hospital Genl Gregorio Maranon /ID# 165162

location_facility: Hospital Universitario Madrid /ID# 165163

location_facility: Vanderbilt University Med Ctr /ID# 162916

location_facility: Washington University-School of Medicine /ID# 161011

location_facility: Asklepios Fachkliniken M. Gaut /ID# 165183


title: A Phase 3 Multicenter, Long-Term Extension Study to Evaluate the Safety and Efficacy of Upadacitinib (ABT-494) in Subjects With Ulcerative Colitis

summary: This study is designed to evaluate the long-term safety and efficacy of Upadacitinib in participants with ulcerative colitis (UC) who have not responded at the end of the induction period in Study M14-234 Substudy 1, who have had loss of response during the maintenance period of Study M14-234 Substudy 3, or who have successfully completed Study M14-234 Substudy 3.

status: Enrolling by invitation

location_country:
Finland
Malaysia
Greece
Australia
Belgium
Russian Federation
Taiwan
Ukraine
Spain
Croatia
France
Japan
Lithuania
Poland
Norway
Slovakia
Argentina
Canada
Korea, Republic of
Turkey
Colombia
South Africa
Chile
Sweden
Switzerland
Netherlands
Singapore
Hungary
Ireland
Puerto Rico
China
Portugal
Germany
United States
United Kingdom
Italy
Austria
Bosnia and Herzegovina
Brazil
Serbia
Mexico
Czechia
Israel
Belarus
Estonia
Latvia

location_facility: Medizinisches Versorgungszentrum Portal 10 /ID# 207136

location_facility: Markusovszky Egyetemi Oktatokorhaz /ID# 150410

location_facility: Hospital de Clinicas de Porto Alegre /ID# 153745

location_facility: CHRU Lille - Hopital Claude Huriez /ID# 152609

location_facility: Gastroenterology Associates, P.A. /ID# 150557

location_facility: Hospital of Lithuanian University of Health Sciences Kaunas Clinics /ID# 150439

location_facility: Hospital Universitario La Paz /ID# 214541

location_facility: Klinicki bolnicki centar Zagreb /ID# 150715

location_facility: Clinica de Investigacion en Reumatologia y Obesidad S.C. /ID# 202334

location_facility: Clinical Hosp Center Zvezdara /ID# 150641

location_facility: The 2nd Affiliated Hospital and Yuying Children's Hospital of WMU /ID# 217557

location_facility: Texas Digestive Disease Consultants - Cedar Park /ID# 209949

location_facility: Medical Center of the "Health /ID# 162501

location_facility: Allen Whey Khye Lim Professional Corporation /ID# 211169

location_facility: University Clinical Centre of the Republic of Srpska /ID# 150712

location_facility: East Tennessee Research Instit /ID# 203611

location_facility: Yamanashi Prefectural Central Hospital /ID# 151909

location_facility: Hospital Clinico Universitario de Salamanca /ID# 150590

location_facility: Montefiore Medical Center - Moses Campus /ID# 150559

location_facility: Chung Shan Medical University /ID# 150603

location_facility: Medical centre of CONSILIUM MEDICAL LLC /ID# 217448

location_facility: Klinicki bolnicki centar Rijeka /ID# 150714

location_facility: Univ of California San Francis /ID# 164583

location_facility: Inland Empire Liver Foundation /ID# 216163

location_facility: Consultants for Clinical Res /ID# 151683

location_facility: Basingstoke & North Hampshire /ID# 150511

location_facility: General Hospital of Chest Diseases of Athens SOTIRIA /ID# 202101

location_facility: Bekes Megyei Kozponti Korhaz /ID# 151601

location_facility: Hadassah Medical Center-Hebrew University /ID# 165119

location_facility: Ohio Clinical Research Partner /ID# 154074

location_facility: Hospital Guillermo Grant Benavente de Concepción /ID# 212425

location_facility: Atrium Health Carolinas Medical Center /ID# 157060

location_facility: Tyler Research Institute, LLC /ID# 169147

location_facility: Kaiser Clinica e Hospital Dia /ID# 152491

location_facility: Istanbul University Cerrahpasa Faculty of Medicine /ID# 150491

location_facility: Juntendo University Urayasu Hospital /ID# 208783

location_facility: Nagoya City University Hospital /ID# 151949

location_facility: University of Michigan Health Systems /ID# 151158

location_facility: Univ Hospitals Birmingham NHS Foundation trust /ID# 150513

location_facility: National University Hospital /ID# 150583

location_facility: West Tallinn Central Hospital /ID# 150490

location_facility: Shanghai Tenth People's Hosp /ID# 150522

location_facility: Ventura County Gastroenterology /ID# 163417

location_facility: Ctr for Advanced Gastroenterol /ID# 202018

location_facility: Hospital Garcia de Orta, E.P.E /ID# 151622

location_facility: MNI Odesa Regional Clinical Hospital of ORC /ID# 162502

location_facility: The Sixth Affiliated Hosp Sun /ID# 150518

location_facility: ASST Fatebenefratelli Sacco - Ospedale Fatebenefratelli e Oftalmico /ID# 150605

location_facility: University Clinical Center Tuzla /ID# 150224

location_facility: Asahikawa Medical University Hospital /ID# 170281

location_facility: Hospital Universitario Dr. Negrin /ID# 203965

location_facility: Clinical Center University of Sarajevo /ID# 150222

location_facility: Centre Hospitalier Universitaire de Nice - Hopital l'Archet 2 /ID# 152608

location_facility: Medizinische Universitat Wien /ID# 150616

location_facility: Soroka University Medical Center /ID# 156562

location_facility: Hospital Nossa Senhora das Graças /ID# 152488

location_facility: Affiliated Taihe Hospital of Hubei University of Medicine /ID# 216407

location_facility: General Hospital of Athens Evaggelismos and Ophthalmiatrio of Athens Polyclinic /ID# 150406

location_facility: Klinicka bolnica Dubrava Zagreb /ID# 150228

location_facility: Showa University Fujigaoka Hospital /ID# 208223

location_facility: Washington University-School of Medicine /ID# 150537

location_facility: Wisconsin Center for Advanced Research, a division of GI Associates, LLC /ID# 151845

location_facility: National Taiwan University Hospital /ID# 150604

location_facility: Marmara University Medical Fac /ID# 214573

location_facility: Inst Med Alta Tec Onc (IMAT) /ID# 207052

location_facility: Kyiv Municipal Clinical Hospital #18 /ID# 150505

location_facility: Atlantic Digestive Health Inst /ID# 150527

location_facility: Southern Therapy and Advanced Research (STAR) LLC /ID# 170713

location_facility: Hospital Privado Univesitario /ID# 164186

location_facility: Hiroshima University Hospital /ID# 151952

location_facility: Mentahaz Maganorvosi Kozpont /ID# 206977

location_facility: Union Hospital Tongji Medical College Huazhong University of Science and Technol /ID# 167079

location_facility: Hospital das Clinicas da Faculdade de Medicina de Ribeirão Preto - USP /ID# 152492

location_facility: National Cheng Kung University Hospital /ID# 151751

location_facility: Ruijin Hospital, Shanghai Jiaotong /ID# 150523

location_facility: Japanese Red Cross Osaka Hospital /ID# 209477

location_facility: Medak s.r.o., gastroenterologi /ID# 150550

location_facility: Immanuel Kant Baltic Federal University /ID# 202129

location_facility: Yamagata University Hospital /ID# 171468

location_facility: University Clinical Hospital Mostar /ID# 150711

location_facility: Aurora Medical Center - Grafto /ID# 151726

location_facility: University General Hospital of Ioannina /ID# 164247

location_facility: Nature Coast Clinical Research - Inverness /ID# 154070

location_facility: The second affiliated hospital of Zhejiang University school of medicine /ID# 165813

location_facility: CB Flock Research Corporation /ID# 165986

location_facility: LLC Medical Company Hepatolog /ID# 200208

location_facility: Universitaetsklinikum Schleswig-Holstein /ID# 161871

location_facility: Newport Huntington Medical Group /ID# 217006

location_facility: Instituto Goiano de Gastroenterologia e Endoscopia Digestiva Ltda /ID# 153744

location_facility: Hospital Universitario Ramon y Cajal /ID# 171491

location_facility: National Hospital Organization Sendai Medical Center /ID# 209529

location_facility: Hamamatsu University Hospital /ID# 205709

location_facility: Hyogo College of Medicine College Hospital /Id# 152433

location_facility: Centro Hospitalar de Entre o D /ID# 152336

location_facility: Tianjin Med Univ General Hosp /ID# 170605

location_facility: Soproni Erzsebet Oktato Korhaz es Rehabilitacios Intezet /ID# 151599

location_facility: National Hospital Organization Higashi-Ohmi General Medical Center /ID# 210711

location_facility: East Tallinn Central Hospital /ID# 150488

location_facility: Osaka City University Hospital /ID# 152681

location_facility: CliniCore International, LLC /ID# 152078

location_facility: Queen Elizabeth University Hos /ID# 163788

location_facility: Kazan State Medical University /ID# 166040

location_facility: Gastroenterologische Gemeinschaftspraxis Herne /ID# 214575

location_facility: Morales Vargas Centro de Investigacion S.C. /ID# 211327

location_facility: The First Affiliated Hospital of Soochow University /ID# 217981

location_facility: Centro Regiomontano de Estudios Clínicos ROMA S.C /ID# 150265

location_facility: Kaohsiung Medical University Chung-Ho Memorial Hospital /ID# 150606

location_facility: Riga East Clinical Univ Hosp /ID# 150436

location_facility: Reumatika - Centrum Reumatologii NZOZ /ID# 150624

location_facility: Houma Digestive Health Special /ID# 151851

location_facility: Agaplesion Markus Krankenhaus /ID# 161870

location_facility: Centro Hosp de Lisboa Central /ID# 151620

location_facility: Centro de Investigaciones Clínicas Viña del Mar /ID# 150226

location_facility: M y F Estudios Clínicos Ltda. /ID# 200112

location_facility: Taipei Veterans General Hosp /ID# 151750

location_facility: Universal Axon Clinical Resear /ID# 213463

location_facility: Japanese Red Cross Kyoto Daiichi Hosital /ID# 152358

location_facility: Umraniye Training and Res Hosp /ID# 163136

location_facility: Universitaetsklinikum Tuebingen /ID# 151698

location_facility: Universitetssykehuset Nord-Norge /ID# 152836

location_facility: Yokkaichi Hazu Hazu Medical Center /ID# 214349

location_facility: Vinnytsia Regional Clinical Hospital n.a. M.I.Pyrogov /ID# 216302

location_facility: Clin Res Inst of Michigan, LLC /ID# 153031

location_facility: Cotton-O'Neil Clinical Res Ctr /ID# 167183

location_facility: A.O.U. Policlinico S.Orsola-Malpighi /ID# 150424

location_facility: Sapporo Medical University Hospital /ID# 206493

location_facility: Indianapolis Gastroenterology /ID# 162914

location_facility: P. Stradins Clinical Univ Hosp /ID# 153183

location_facility: Niigata University Medical & Dental Hospital /ID# 218050

location_facility: Wits Health Consortium (Pty) Ltd /ID# 157730

location_facility: Arizona Arthritis & Rheumatolo /ID# 169823

location_facility: Digestive Health Partners, P.A /ID# 167238

location_facility: Mautalen Salud e Investigacion /ID# 171174

location_facility: University General Hospital of Heraklion PA.G.N.I /ID# 150236

location_facility: Tongji Hospital Tongji Medical College Huazhong University of Science and Techno /ID# 167089

location_facility: Shengjing Hospital of China Medical University /ID# 166921

location_facility: Instytut Pomnik - Centrum Zdrowia Dziecka /ID# 215733

location_facility: Fakultna nemocnica s poliklinikou F.D. Roosevelta Banska Bystrica /ID# 150869

location_facility: Unidade Local De Saude Do Alto Minho /ID# 151618

location_facility: Centralny Szpital Kliniczny MSWiA w Warszawie /ID# 150627

location_facility: Hospital Clinico Universidad De Los Andes /ID# 207427

location_facility: Massachusetts General Hospital /ID# 165678

location_facility: Nemocnice Pardubickeho kraje, a.s. /ID# 213541

location_facility: Hometown Urgent Care and Resea /ID# 200066

location_facility: Helsinki Univ Central Hospital /ID# 154283

location_facility: Kitakyushu Municipal Med Ctr /ID# 152589

location_facility: Gastrointestinal Biosciences /ID# 157082

location_facility: United Gastroenterologists - Murrieta /ID# 151213

location_facility: Kitasato University Kitasato Institute Hospital /ID# 152687

location_facility: Southern Star Research Institute, LLC /ID# 169397

location_facility: University Clinical Centre of the Republic of Srpska /ID# 150223

location_facility: Krankenanstalt Rudolfstiftung /ID# 162867

location_facility: Hospital Senhora da Oliveira de Guimaraes, EPE /ID# 151616

location_facility: Clinical Associates in Researc /ID# 167954

location_facility: Inselspital, Universitaetsklinik /ID# 152602

location_facility: Texas Digestive Disease Consultants - Cedar Park /ID# 209806

location_facility: Zentrum für Gastroenterologie Saar MVZ GmbH /ID# 215812

location_facility: A.O. Ospedali Riuniti Villa Sofia - Cervello /ID# 150263

location_facility: Baylor Scott & White Health - Temple /ID# 204777

location_facility: Lenasia Clinical Trial Centre /ID# 214361

location_facility: Leids Universitair Medisch Centrum /ID# 152625

location_facility: The First Affiliated Hospital of Nanchang University /ID# 212185

location_facility: Yokohama City University Medical Center /ID# 169900

location_facility: Sapporo Higashi Tokushukai Hospital /ID# 208495

location_facility: Louisana Research Center, LLC /ID# 150526

location_facility: Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico /ID# 150421

location_facility: National Hospital Organization Mito Medical Center /ID# 152626

location_facility: Faculdade de Medicina do ABC /ID# 152489

location_facility: NW State Medical Univ na Mechn /ID# 169332

location_facility: University of Maryland Med Ctr /ID# 150529

location_facility: Saiseikai Fukuoka Genaral Hospital /ID# 209481

location_facility: Renji Hospital, Shanghai Jiaotong University School of Medicine /ID# 165826

location_facility: Universitatsklinikum Mannheim /ID# 150405

location_facility: Quality Medical Research, PLLC /ID# 203427

location_facility: CHU de Saint-Etienne, Hopital Nord /ID# 165756

location_facility: Center Hospital of the National Center for Global Health and Medicine /ID# 209533

location_facility: Northwest Gastroenterology Cli /ID# 152528

location_facility: The First Hosp of Jilin Univ /ID# 210087

location_facility: Hospital Universitario A Coruña - CHUAC /ID# 203912

location_facility: General Hospital of Thessaloniki Hippokrateio /ID# 209522

location_facility: Delsol Research Management, Ll /Id# 170130

location_facility: AGA Clinical Research Associates, LLC /ID# 153048

location_facility: Dayton Gastroenterology, Inc. /ID# 167632

location_facility: Moonshine Research Center, Inc /ID# 152534

location_facility: Complesso integrato Columbus /ID# 150420

location_facility: Ishida Clinic of IBD and Gastroenterology /ID# 210118

location_facility: Klinicki bolnicki centar Split /ID# 213989

location_facility: South Denver Gastroenterology /ID# 151224

location_facility: NorthShore University HealthSystem - Evanston Hospital /ID# 150570

location_facility: Baylor Scott & White Research /ID# 200771

location_facility: West China Hospital, Sichuan University /ID# 167041

location_facility: Toho University Sakura Medical Center /ID# 151935

location_facility: Crystal Pharmacology Research /ID# 151848

location_facility: UOSD - Azienda Ospedaliera San Camillo Forlanini /ID# 151362

location_facility: Toronto Digestive Disease Asso /ID# 150475

location_facility: Plains Clinical Research Center, LLC /ID# 170291

location_facility: Corporacion Hospitalaria Juan Ciudad sede Denominada Hospital Universitario Mayo /ID# 152811

location_facility: West Central Gastroenterology /ID# 155242

location_facility: Universitair Medisch Centrum Utrecht /ID# 152776

location_facility: Nemocnice Milosrdnych sester sv. Karla Boromejskeho v Praze /ID# 216224

location_facility: Next Innovative Clinical Research - Chicago /ID# 217323

location_facility: Columbia Univ Medical Center /ID# 163409

location_facility: TX Clinical Research Institute /ID# 151528

location_facility: Tsujinaka Hospital Kashiwanoha /ID# 209572

location_facility: Centro Hospitalar de Sao Joao, EPE /ID# 151619

location_facility: Slovak Research Center Team Me /ID# 150240

location_facility: Fujita Gastroenterological Hos /ID# 216494

location_facility: Fakultna nemocnica s poliklini /ID# 211371

location_facility: Perm Clinical Center of FMBA /ID# 150634

location_facility: Republican Clin Hos n.a. Baran /ID# 206508

location_facility: Klaipeda University Hospital /ID# 163719

location_facility: Aichi Medical University Hospital /ID# 151994

location_facility: Minnesota Gastroenterology P.A /ID# 151682

location_facility: Hospital Universitario y Politecnico La Fe /ID# 150591

location_facility: Northwest Health Care Associat /ID# 151591

location_facility: Montreal General Hospital - McGill University Health Centre /ID# 170013

location_facility: The First Affiliated Hosp, Sun /ID# 150517

location_facility: Huron Gastroenterology Assoc /ID# 152712

location_facility: Akershus Universitetssykehus_MAIN /ID# 150622

location_facility: Ordensklinikum Linz GmbH, Barmherzige Schwestern /ID# 150462

location_facility: Hokkaido P.W.F.A.C. Sapporo-Kosei General Hospital /ID# 151705

location_facility: Virginia Mason Medical Center /ID# 153030

location_facility: Carl R. Meisner Medical Clinic /ID# 171270

location_facility: Options Health Research, LLC /ID# 150569

location_facility: Ospedale Classificato Equiparato Sacro Cuore-Don Calabria /ID# 201726

location_facility: Atlanta Gastroenterology Spec /ID# 150565

location_facility: Hospital Universitario de San /ID# 155388

location_facility: Kanazawa University Hospital /ID# 207810

location_facility: School of Medicine University of Puerto Rico-Medical Science Campus /ID# 150629

location_facility: Chikuba Hospital for Proctological and Gastrointestinal Diseases /ID# 157820

location_facility: PE PMC Acinus, Medical and Diagnostic Center /ID# 217219

location_facility: Trinity College Dublin - St. J /ID# 150413

location_facility: University of Iowa Hospitals and Clinics /ID# 157059

location_facility: Percuro Clinical Research, Ltd /ID# 150479

location_facility: McMaster University Med Cent /ID# 150477

location_facility: North Estonian Medical Centre /ID# 160871

location_facility: Clinical Research Trials of Florida, Inc. /ID# 201791

location_facility: Radboud Universitair Medisch Centrum /ID# 151701

location_facility: Ctr for Gastrointestinal Healt /ID# 153369

location_facility: Toyohashi Municipal Hospital /ID# 171470

location_facility: Hospital Unversitario Marques de Valdecilla /ID# 216621

location_facility: The Catholic University of Korea St. Vincent's Hospital /ID# 150434

location_facility: Pusan National University Hosp /ID# 161569

location_facility: IBD Center - IRCCS Istituto Clinico Humanitas /ID# 151363

location_facility: Iwate Medical University Uchimaru Medical Center /ID# 203412

location_facility: Clin Hosp Ctr Bezanijska Kosa /ID# 150640

location_facility: East View Medical Research, LLC /ID# 171184

location_facility: Erciyes University Medical Fac /ID# 150495

location_facility: University of Calgary Cumming School of Medicine Adult Cystic Fibrosis Clinic /ID# 151818

location_facility: Communal Non-Commercial Enterprize of Kharkiv Regional Council Regional Clinical /ID# 206941

location_facility: Regional Clin Hosp Mechnykov /ID# 207731

location_facility: Great Lakes Gastroenterology Research LLC /ID# 201773

location_facility: Dartmouth-Hitchcock Medical Center /ID# 150566

location_facility: Tokyo Medical And Dental University, Medical Hospital /ID# 152017

location_facility: Tokai University Hachioji Hospital /ID# 152584

location_facility: Richmond University Medical Center /ID# 201860

location_facility: Hospital Universitario Reina Sofia /ID# 154031

location_facility: Wake Forest Baptist Medical Center /ID# 150528

location_facility: Hanyang University Guri Hosp /ID# 150431

location_facility: Healthcare Research Consultant /ID# 163096

location_facility: Medical College of Wisconsin /ID# 151850

location_facility: Charlotte Gastroenterology and Hepatology, PLLC /ID# 150561

location_facility: Gastroenterology Associates of Central Georgia, LLC /ID# 165783

location_facility: Theageneio Anticancer Hospital /ID# 164187

location_facility: Hepato-Gastroenterologie HK s.r.o. /ID# 150946

location_facility: Centro Hospitalar Lisboa Norte, EPE /ID# 151615

location_facility: St Vincent's University Hosp /ID# 150411

location_facility: Xiangya Hospital Central South University /ID# 167230

location_facility: Vitebsk Regional Advanced Clin /ID# 169592

location_facility: Klinicki bolnicki centar Osijek /ID# 150229

location_facility: Advanced Clinical Research (ACR) - Salt Lake City /ID# 163180

location_facility: Revival Research Institute, LLC /ID# 207281

location_facility: CCA Braga - Hospital de Braga /ID# 151617

location_facility: Lviv Regional Clinical Hospita /ID# 150508

location_facility: Academisch Medical center Amsterdam /ID# 150617

location_facility: Hospital Clínico Universitario de Santiago-CHUS /ID# 171492

location_facility: Gastroenterology Associates of Western Michigan, PLC /ID# 157487

location_facility: DiGiovanna Institute for Medical Education & Research /ID# 201534

location_facility: Digestive Disease Specialists /ID# 201057

location_facility: Citrus Valley Gastroenterology /ID# 151915

location_facility: Western Connecticut Medical Group /ID# 169211

location_facility: Stavropol State Medical Univ /ID# 150635

location_facility: The Vancouver Clinic, INC. PS /ID# 162334

location_facility: Huddersfield Royal Infirmary /ID# 217659

location_facility: Gazi Universitesi Tip Fakultes /ID# 150493

location_facility: Duplicate_Western States Clinical Res /ID# 158078

location_facility: Shimane University School of Medicine /ID# 208906

location_facility: St.Luke's International Hospital /ID# 208075

location_facility: General Hospital of Athens Laiko /ID# 208672

location_facility: China Medical University Hosp /ID# 150600

location_facility: NYU Langone Long Island Clin. Res. Assoc. /ID# 155271

location_facility: Tokyo Women's Medical University Hospital /ID# 205978

location_facility: St. Marianna University School of Medicine Hospital /ID# 209452

location_facility: MediSphere Medical Research Center /ID# 152080

location_facility: Universitatsklinikum Munster /ID# 150402

location_facility: Fukuoka University Chikushi Hospital /ID# 152627

location_facility: Centex Studies, Inc. - Houston /ID# 201217

location_facility: Klinicki bolnicki centar Zagreb /ID# 150262