lead_sponsor: AbbVie

summary:
The objectives of Sub-Study 1 are to evaluate the efficacy, safety, and pharmacokinetics of risankizumab as induction treatment in subjects with moderately to severely active ulcerative colitis (UC), and to identify the appropriate induction dose of risankizumab for further evaluation in Sub-Study 2.

The objective of Sub-Study 2 is to evaluate the efficacy and safety of risankizumab compared to placebo in inducing clinical remission in subjects with moderately to severely active UC.

location_facility: Southern California Res. Ctr. /ID# 169660

location_facility: Consorci Corporacio Sanitaria Parc Tauli Sabadell /ID# 159461

location_facility: Fakultna nemocnica s poliklinikou Nove Zamky /ID# 224099

location_facility: Klinicki bolnicki centar Zagreb /ID# 201917

location_facility: Royal Devon University Healthcare NHS Foundation Trust /ID# 157587

location_facility: CHU Bordeaux - Hopital Haut Leveque /ID# 171579

location_facility: Hospital of Lithuanian University of Health Sciences Kaunas Clinics /ID# 170714

location_facility: Hadassah Medical Center-Hebrew University /ID# 171099

location_facility: Pauls Stradins Clinical University Hospital /ID# 163803

location_facility: Hospital Garcia de Orta, EPE /ID# 165583

location_facility: Taichung Veterans General Hospital /ID# 163649

location_facility: Clin Hosp Ctr Bezanijska Kosa /ID# 202059

location_facility: KL Ling Gastroenterology and Liver Clinic /ID# 205738

location_facility: Kanazawa University Hospital /ID# 169224

location_facility: Kitasato University Kitasato Institute Hospital /ID# 164256

location_facility: Hospital das Clinicas da Faculdade de Medicina de Ribeirao Preto - USP /ID# 157660

location_facility: Renji Hospital, Shanghai Jiaotong University School of Medicine /ID# 211233

location_facility: King's College Hospital NHS Foundation Trust /ID# 158766

location_facility: University of Rochester Medical Center /ID# 161664

location_facility: Bispebjerg and Frederiksberg Hospital /ID# 208945

location_facility: Tyler Research Institute, LLC /ID# 166800

location_facility: The Jikei University Hospital /ID# 164434

location_facility: Hyogo Medical University Hospital /ID# 164424

location_facility: IRCCS Ospedale Sacro Cuore Don Calabria /ID# 164041

location_facility: Kyiv Municipal Clinical Hospital #18 /ID# 224348

location_facility: National Hospital Organization Takasaki General Medical Center /ID# 164437

location_facility: Cedars-Sinai Medical Center-West Hollywood /ID# 163851

location_facility: Hospital Provincial del Centenario /ID# 170898

location_facility: Groupe Sante CHC - Clinique du MontLegia /ID# 200250

location_facility: South Lake Pain Institute, Inc /ID# 162878

location_facility: Medical Research Center of CT /ID# 160311

location_facility: Cambridge University Hospitals NHS Foundation Trust /ID# 158040

location_facility: West China Hospital, Sichuan University /ID# 211276

location_facility: Soroka University Medical Center /ID# 171100

location_facility: H-T. Centrum Medyczne - Endoterapia /ID# 230979

location_facility: Peak Gastroenterology Associates, PC /ID# 165841

location_facility: Baylor Scott & White Center for Diagnostic Medicine /ID# 204130

location_facility: Lenus Research & Medical Group /ID# 169730

location_facility: London Health Sciences Center /ID# 169103

location_facility: Hospital Nossa Senhora das Graças /ID# 157671

location_facility: Ospedale Policlinico San Martino /ID# 164031

location_facility: Cabinet Particular Policlinic Algomed /ID# 171266

location_facility: Texas Digestive Disease Consultants /ID# 209950

location_facility: Cliniques Universitaires de Bruxelles Hopital Erasme /ID# 200252

location_facility: Kitasato University Hospital /ID# 169226

location_facility: Caprock Gastro Research, LLC /ID# 215432

location_facility: Clinic of New Technologies of Medicine /ID# 203369

location_facility: Virginia Mason Medical Center /ID# 160466

location_facility: Klinicki bolnicki centar Osijek /ID# 157472

location_facility: Shengjing Hospital of China Medical University /ID# 211646

location_facility: ASST Grande Ospedale Metropolitano Niguarda /ID# 170947

location_facility: MVZ fuer Gastroenterlogie am Bayerischen Platz /ID# 159361

location_facility: The First Affiliated Hospital of Nanchang University /ID# 212183

location_facility: Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty /ID# 167207

location_facility: Hospital Alvaro Cunqueiro CHUVI /ID# 167360

location_facility: Gastrointestinal Biosciences Clinical Trials, LLC /ID# 200931

location_facility: Gastro Health & Nutrition - Victoria /ID# 164321

location_facility: Yokkaichi Hazu Medical Center /ID# 164441

location_facility: International Medical Center SOGAZ /ID# 206727

location_facility: Praxis fuer Gastroenterologie /ID# 166152

location_facility: Tzaneio general hospital of Piraeus /ID# 206439

location_facility: Kuzbass Regional Clinical Hospital /ID# 165750

location_facility: Houma Digestive Health Special /ID# 158317

location_facility: CIUSSS de l'est de l'Ile-de-Montreal - Hopital Maisonneuve-Rosemont /ID# 169108

location_facility: Sahlgrenska University Hospital Molndal /ID# 202843

location_facility: Gastroenterology Consultants of Southwest Virginia /ID# 218143

location_facility: Vitamed Gałaj i Cichomski Sp.j. /ID# 213283

location_facility: St George's University Hospitals NHS Foundation Trust /ID# 208378

location_facility: Municipal Nonprofit Enterprise Kherson city clinical hospital n.a. Y.Y. Karabel /ID# 224350

location_facility: Erciyes University Medical Fac /ID# 171291

location_facility: UCSF Center for Colitis and Crohn's Disease /ID# 201210

location_facility: DM Clinical Research/Southwest /ID# 165012

location_facility: Universitatsklinikum Mannheim /ID# 162035

location_facility: CliniCore International, LLC /ID# 158218

location_facility: Southern Star Research Institute, LLC /ID# 168776

location_facility: Medizinische Universitaet Graz /ID# 169053

location_facility: Hospital Privado Univesitario /ID# 167779

location_facility: Inje University Haeundae Hospital /ID# 203028

location_facility: DiGiovanna Institute for Medical Education & Research /ID# 171129

location_facility: Hepato-Gastroenterologie HK, s.r.o. /ID# 163395

location_facility: Digestive Disease Associates, LTD /ID# 232407

location_facility: The First Hospital of Jilin University /ID# 212278

location_facility: Chu de Nice-Hopital L'Archet Ii /Id# 171577

location_facility: Fakultni nemocnice u sv. Anny v Brne /ID# 239157

location_facility: Universitair Ziekenhuis Leuven /ID# 170812

location_facility: Toho University Sakura Medical Center /ID# 164254

location_facility: Digestive Disease Specialists /ID# 170779

location_facility: UOC Medicina Interna e Gastroe /ID# 155608

location_facility: University of Michigan Comprehensive Cancer Center Michigan Medicine /ID# 158524

location_facility: General Hospital of Chest Diseases of Athens SOTIRIA /ID# 170915

location_facility: University Clinical Center Serbia /ID# 200152

location_facility: Narodowy Instytut Onkologii im. Marii Skłodowskiej-Curie Panstwowy Instytut Bada /ID# 170600

location_facility: Uludag University Medical Faculty /ID# 204182

location_facility: Wellington Regional Hospital /ID# 205343

location_facility: Gastroenterologie Opernstrasse /ID# 163683

location_facility: CHRU Nancy - Hopitaux de Brabois /ID# 200095

location_facility: General Hospital of Nikaia-Piraeus "Agios Panteleimon"- general hospital dytikis /ID# 165218

location_facility: Hospital Universitario Puerta de Hierro, Majadahonda /ID# 159443

location_facility: Ulyanovsk Regional Clinical Hospital /ID# 203368

location_facility: General Hospital of Athens Laiko /ID# 206440

location_facility: ProMedica Physicians Digestive Healthcare /ID# 215623

location_facility: The University of Chicago Medical Center /ID# 160521

location_facility: Yonsei University Health System Severance Hospital /ID# 158701

location_facility: Adult Gastroenterology Associates - Gen 1 Research /ID# 208867

location_facility: Charite Universitaetsklinikum Berlin - Campus Benjamin Franklin /ID# 210510

location_facility: Fukuoka University Chikushi Hospital /ID# 209055

location_facility: Barnsley Hospital NHS Foundation Trust /ID# 202770

location_facility: Clinical Research Center, Faculty of Medicine, Alexandria university. /ID# 226794

location_facility: University General Hospital of Heraklion PA.G.N.I /ID# 165216

location_facility: Ruijin Hospital, Shanghai Jiaotong University School of Medicine /ID# 210962

location_facility: Azienda Ospedaliera Universitaria Policlinico Tor Vergata /ID# 158018

location_facility: Baylor College of Medicine - Baylor Medical Center /ID# 158221

location_facility: Inselspital, Universitätsspital Bern /ID# 202911

location_facility: Private Practice Dr MN Rajabally /ID# 171137

location_facility: Hospital Universitario La Paz /ID# 159459

location_facility: Hospital Universitario de Salamanca /ID# 159446

location_facility: Texas Digestive Disease Consultants /ID# 209798

location_facility: Gastroenterology Associates of Central Georgia, LLC /ID# 160523

location_facility: Elisabeth Tweesteden Ziekenhuis /ID# 163767

location_facility: Clinical Hospital Center Dr Dragisa Misovic - Dedinje /ID# 224926

location_facility: Precision Research Institute, LLC /ID# 201351

location_facility: Tangdu Hospital of The Fourth Military Medical University, PLA /ID# 215504

location_facility: Clinical Hosp Center Zvezdara /ID# 200151

location_facility: Chung Shan Medical University Hospital /ID# 163651

location_facility: Nagoya City University Hospital /ID# 164331

location_facility: Universitaetsklinikum Erlangen /ID# 159354

location_facility: The second Affiliated hospital of Zhejiang University school of Medicine /ID# 211025

location_facility: Centre Médico Chirurgical Ambroise Paré Hartmann /ID# 249860

location_facility: Vilnius University Hospital Santaros Klinikos /ID# 170614

location_facility: LMU Klinikum Campus Grosshadern /ID# 210481

location_facility: GBUZ Allergology and Immunology Center of Ministry of Health of Kabardino-Bal /ID# 233973

location_facility: Medizinische Universitaet Wien /ID# 169050

location_facility: Centro Hosp de Tondela-Viseu /ID# 166053

location_facility: Percuro Clinical Research, Ltd /ID# 169109

location_facility: Japanese Red Cross Wakayama Medical Center /ID# 171195

location_facility: Sir Run Run Shaw Hospital,Meical School Zhejiang University /ID# 211064

location_facility: Vanderbilt University Medical Center /ID# 160580

location_facility: Centralny Szpital Kliniczny MSWiA w Warszawie /ID# 170601

location_facility: Universitaetsklinikum Schleswig-Holstein Campus Kiel /ID# 159360

location_facility: Health Pharma Professional Research S.A de C.V /ID# 203597

location_facility: Hanyang University Gurihospital /ID# 158702

location_facility: Hiroshima University Hospital /ID# 164426

location_facility: Regional Clinical Hospital #1 /ID# 165754

location_facility: CHU de SAINT ETIENNE - Hopital Nord /ID# 171580

location_facility: Gastroenterologische Gemeinschaftspraxis Minden /ID# 162033

location_facility: The Catholic University of Korea, Daejeon St.Mary's Hospital /ID# 242378

location_facility: Sisli Etfal Train & Res Hosp /ID# 171409

location_facility: Penn State Milton S. Hershey Medical Center /ID# 223563

location_facility: Kobenhavns Universitet - Hvidovre Hospital (HH) /ID# 202266

location_facility: Duplicate_Centrul Medical Tuculanu SRL /ID# 171268

location_facility: Complejo Hospitalario Universitario de Pontevedra /ID# 216182

location_facility: Clinical Research Center, Faculty of Medicine, Alexandria university. /ID# 200848

location_facility: Colo-proctology Center Matsushima Clinic /ID# 225914

location_facility: Cotton-O'Neil Clinical Res Ctr /ID# 160412

location_facility: Second Multiprofile Hospital f /ID# 200799

location_facility: Advanced Research Institute, Inc /ID# 161938

location_facility: Azienda Ospedaliera San Camillo Forlanini /ID# 155612

location_facility: Marmara Universitesi Pendik Egitim ve Arastirma Hastanesi /ID# 171293

location_facility: UMHAT Tsaritsa Joanna - ISUL /ID# 209977

location_facility: Hospital Universitario Reina Sofia /ID# 167058

location_facility: Robley Rex VA Medical Center /ID# 218648

location_facility: Clinical Research Trials of Florida, Inc. /ID# 201783

location_facility: National Medical Research Center of Coloproctology n.a. A. N. Ryzhikh /ID# 203512

location_facility: Yale Univ Digestive Diseases /ID# 213179

location_facility: CHU Amiens-Picardie Site Sud /ID# 171576

location_facility: Hokkaido P.W.F.A.C. Sapporo-Kosei General Hospital /ID# 164251

location_facility: Taipei Veterans General Hosp /ID# 163650

location_facility: Huai'an First People's Hospital /ID# 239196

location_facility: Clin Res Inst of Michigan, LLC /ID# 160327

location_facility: Complejo Asistencial Dr. Sotero del Rio /ID# 169385

location_facility: Sapporo Medical University Hospital /ID# 164432

location_facility: St. Marianna University Hospital /ID# 226728

location_facility: Sapporo Higashi Tokushukai Hospital /ID# 208488

location_facility: Pusan National University Hospital /ID# 158711

location_facility: Servicio de Salud Occidente Hospital San Juan de Dios /ID# 171125

location_facility: Centro Hospitalar e Universitario de Coimbra, EPE /ID# 166054

location_facility: Toronto Digestive Disease Asso /ID# 169106

location_facility: The First Affiliated Hospital of Anhui Medical University /ID# 211228

location_facility: Theageneio Anticancer Hospital /ID# 165217

location_facility: ASST Fatebenefratelli Sacco-Ospedale Sacco /ID# 155607

location_facility: Hospital da Senhora da Oliveira Guimaraes, EPE /ID# 165580

location_facility: Hospital Universitario Miguel Servet /ID# 159445

location_facility: Plains Clinical Research Center, LLC /ID# 169732

location_facility: Centro Hospitalar Universitário do Algarve, EPE - Hospital de Portimão /ID# 166551

location_facility: Hospital Clinic de Barcelona /ID# 159439

location_facility: Tsujinaka Hospital Kashiwanoha /ID# 208964

location_facility: Tokyo Medical And Dental University Hospital /ID# 164258

location_facility: St.Luke's International Hospital /ID# 225822

location_facility: CHA University Bundang Medical Center /ID# 158710

location_facility: Kaiser Clinica e Hospital Dia /ID# 157680

location_facility: Ordensklinikum Linz GmbH Barmherzige Schwestern /ID# 215320

location_facility: Cleveland Clinic Main Campus /ID# 209232

location_facility: The Sixth Affiliated Hosp Sun /ID# 211231

location_facility: Hospital Arquitecto Marcide - Complejo Hospitalario Universitario de Ferrol /ID# 159440

location_facility: Massachusetts General Hospital - Crohn's and Colitis Center /ID# 164255

location_facility: Hospital Universitario San Vic /ID# 171490

location_facility: Klinicki bolnicki centar Split /ID# 157473

location_facility: The Catholic University of Korea, ST. Vincent's Hospital /ID# 158706

location_facility: Showa University Fujigaoka Hospital /ID# 209555

location_facility: Columbia Univ Medical Center /ID# 161934

location_facility: VA Caribbean Healthcare System /ID# 221245

location_facility: Nara Medical University Hospital /ID# 169225

location_facility: WIP Warsaw IBD Point Profesor Kierkus /ID# 216102

location_facility: Nagasaki University Hospital /ID# 202674

location_facility: National Taiwan University Hospital /ID# 162187

location_facility: Ponce Medical School Foundation /ID# 221244

location_facility: Fırat University Medical Facul /ID# 171292

location_facility: The Second Hospital of Hebei Medical University /ID# 213018

location_facility: Klinicki bolnicki centar Zagreb /ID# 157471

location_facility: Hospital Guillermo Grant Benavente de Concepción /ID# 210761

location_facility: South Florida Research Ph I-IV, Inc. /ID# 161848

location_facility: Hamamatsu University Hospital /ID# 226727

location_facility: Landeskrankenhaus Salzburg-Universitätsklinikum der PMU (LKH) /ID# 200685

location_facility: Renmin Hospital of Wuhan University /ID# 212868

location_facility: Allen Whey Khye Lim Professional Corporation /ID# 169767

location_facility: Atrium Health Carolinas Medical Center /ID# 158512

location_facility: Azienda Ospedaliero-Universitaria di Modena /ID# 201819

location_facility: Asahikawa Medical University Hospital /ID# 164433

location_facility: Centro Hospitalar Universitario Lisboa Central, EPE - Hospital dos Capuchos /ID# 165582

location_facility: Interdisctrict Multidisciplinary Hospital /ID# 203335

location_facility: General Hospital of Athens Evaggelismos and Ophthalmiatrio of Athens Polyclinic /ID# 217480

location_facility: Liverpool University Hospitals NHS Foundation Trust /ID# 203858

location_facility: General Hospital of Ningxia Medical University /ID# 213911

location_facility: Inonu Universitesi Turgut Ozal /ID# 203981

location_facility: General Hospital of Athens Ippokratio /ID# 229189

location_facility: CHU UCL Namur - site Godinne /ID# 200254

location_facility: Centro Hospitalar de Entre Douro e Vouga /ID# 166052

location_facility: Louisana Research Center, LLC /ID# 201204

location_facility: Manhattan Clinical Research, LLC /ID# 211805

location_facility: Shiga University of Medical Science Hospital /ID# 164440

location_facility: Royal Victoria Hospital / McGill University Health Centre /ID# 169104

location_facility: Nemocnice Ceske Budejovice a.s. /ID# 225226

location_facility: China Medical University Hospital /ID# 160189

location_facility: Ctr for Advanced Gastroenterol /ID# 202811

location_facility: Linkou Chang Gung Memorial Hospital /ID# 222877

location_facility: Ospedale Sant Orsola Malpighi /ID# 155611

location_facility: Stadtisches Klinikum Braunschweig /ID# 163687

location_facility: ASST Rhodense/Presidio Ospedaliero di Rho /ID# 211449

location_facility: A.O. Per L'Emergenza Cannizzaro /ID# 164036

location_facility: Scott Shulman Medicine Professional Corporation /ID# 169113

location_facility: Atlanta Gastroenterology Spec /ID# 161372

location_facility: Centex Studies, Inc. - Houston /ID# 201222

location_facility: Faculdade de Medicina do ABC /ID# 163995

location_facility: CHU Montpellier - Hôpital Saint Eloi /ID# 223779

location_facility: Azienda Ospedaliero-Universitaria Policlinico Umberto I /ID# 171226

location_facility: Agaplesion Markus Krankenhaus /ID# 159356

location_facility: Gastroenterology Group Naples /ID# 165212

location_facility: Osaka Medical and Pharmaceutical University Hospital /ID# 226035

location_facility: Aichi Medical University Hospital /ID# 164332

location_facility: Tongji Hospital Tongji Medical College of HUST /ID# 211072

location_facility: Praxiszentrum fuer Gastroenterologie /ID# 219069

location_facility: The Second Xiangya Hospital of Central South University /ID# 211198

location_facility: Yeungnam University Medical Center /ID# 158703

location_facility: CNPE of Kyiv Regional Council Kyiv Regional Hospital /ID# 224343

location_facility: Immanuel Kant Baltic Federal University /ID# 204888

location_facility: Servicio de Salud Araucanía Norte Hospital Victoria /ID# 213151

location_facility: Hoag Memorial Hosp Presbyterian /ID# 218348

location_facility: East Tennessee Research Institute /ID# 168747

location_facility: Universitaetsklinikum Freiburg /ID# 162034

location_facility: Unidad de Atencion Medica e Investigacion en Salud /ID# 203595

location_facility: Fakultna nemocnica s poliklinikou F.D. Roosevelta Banska Bystrica /ID# 164347

location_facility: Clinical Associates in Research Therapeutics of America, LLC /ID# 161376

location_facility: Union Hospital affiliated to Tongji Medical College of Huazhong University of Sc /ID# 211071

location_facility: National Hospital Organization Hirosaki General Medical Center /ID# 164252

location_facility: CNE Regional Clinical Hospital of Ivano-Frankivsk RC /ID# 203367

location_facility: Centro Hospitalar Universitario de Sao Joao, EPE /ID# 165581

location_facility: Rocky Mountain Pediatric Gastroenterology /ID# 207174

location_facility: Quality Clinical Research Inc. /ID# 167313

location_facility: Saiseikai Fukuoka Genaral Hospital /ID# 225639

location_facility: Central Clinical Hospital RZHD Medicine /ID# 204917

location_facility: Clinical Research Center, Faculty of Medicine, Alexandria university. /ID# 226793

location_facility: Air Force Specialized Hospital /ID# 170986

location_facility: First Moscow State Medical University n.a I.M. Sechenov /ID# 204978

location_facility: Universitaetsklinikum Regensburg /ID# 163686

location_facility: Gastroenterologische Spezialpraxis am Wittenbergplatz /ID# 219145

location_facility: Gastroenterology Associates, P.A. of Greenville /ID# 160472

location_facility: Instituto Goiano de Gastroenterologia e Endoscopia Digestiva /ID# 157679

location_facility: Great Lakes Gastroenterology Research, LLC /ID# 201777

location_facility: Gokeikai Ofuna Chuo Hospital /ID# 169300

location_facility: Hospital Universitario Virgen Macarena /ID# 159968

location_facility: The Newcastle Upon Tyne Hospitals NHS Foundation Trust /ID# 158041

location_facility: Tokai University Hachioji Hospital /ID# 226899

location_facility: Fujita Health University Hospital /ID# 164261

location_facility: The Chaim Sheba Medical Center /ID# 211278

location_facility: Duplicate_Universitaetsklinikum St.Poelten /ID# 169048

location_facility: Sjællands Universitetshospital /ID# 200033

location_facility: Perm Clinical Center of the Federal Medical and Biological Agency /ID# 227457

location_facility: University Hospital Southampton NHS Foundation Trust /ID# 210813

location_facility: Fondazione Policlinico Universitario Campus Bio-Medico di Roma /ID# 163992

location_facility: Wakayama Medical University Hospital /ID# 169487

location_facility: Hospital de Clinicas de Porto Alegre /ID# 157662

location_facility: Yamagata University Hospital /ID# 171474

title: A Multicenter, Randomized, Double-Blind, Placebo Controlled Induction Study to Evaluate the Efficacy and Safety of Risankizumab in Subjects With Moderately to Severely Active Ulcerative Colitis

ipd_sharing_description: AbbVie is committed to responsible data sharing regarding the clinical trials we sponsor. This includes access to anonymized, individual and trial-level data (analysis data sets), as well as other information (e.g., protocols, analyses plans, clinical study reports), as long as the trials are not part of an ongoing or planned regulatory submission. This includes requests for clinical trial data for unlicensed products and indications.

location_country:
Germany
Poland
New Zealand
Argentina
Japan
Brazil
Turkey
Croatia
Chile
Czechia
Canada
Serbia
France
Slovenia
Lithuania
Colombia
Portugal
Slovakia
Denmark
Switzerland
United States
Latvia
Ukraine
Romania
Belgium
China
Malaysia
Puerto Rico
Egypt
Italy
United Kingdom
Singapore
Sweden
Netherlands
Austria
Mexico
Korea, Republic of
Spain
Greece
South Africa
Taiwan
Bulgaria
Russian Federation
Israel


study_start_date_type: Actual

intervention_type: Drug

summary:
The purpose of this study is to evaluate safety and efficacy of risankizumab in participants with ulcerative colitis (UC) in participants who responded to induction treatment with risankizumab in a prior AbbVie study of risankizumab in UC.

This study consists of three sub-studies and a Continuous Treatment Extension (CTE): Substudy 1 is a 52-week, randomized, double-blind, placebo-controlled maintenance study; Substudy 2 is 52-week, randomized, exploratory maintenance study; and Substudy 3 is an open-label long-term extension study for participants who completed Substudy 1 or 2, or participants who responded to induction treatment in Study M16-067 with no final endoscopy due to the Covid-19 pandemic or due to the geopolitical conflict in Ukraine and surrounding impacted regions. The CTE is an open-label extension for Substudy 3 completers to ensure continuous treatment with risankizumab until such time that risankizumab becomes commercially available and/or the subject can access treatment locally or can transition to a Continued Treatment for Trial Participants Open-Label Extension study.

location_facility: Clinical Hospital Center Dr Dragisa Misovic - Dedinje /ID# 224927

location_facility: Universitaetsklinikum Schleswig-Holstein Campus Kiel /ID# 159379

location_facility: Fakultna nemocnica s poliklinikou F.D. Roosevelta Banska Bystrica /ID# 164348

location_facility: Elisabeth Tweesteden Ziekenhuis /ID# 163738

location_facility: Manhattan Clinical Research, LLC /ID# 211803

location_facility: Centro Hospitalar Universitario Lisboa Central, EPE - Hospital dos Capuchos /ID# 165578

location_facility: Universitaetsklinikum Freiburg /ID# 162038

location_facility: Gastroenterologische Spezialpraxis am Wittenbergplatz /ID# 219146

location_facility: Tsujinaka Hospital Kashiwanoha /ID# 225968

location_facility: Centro Hospitalar Universitario de Sao Joao, EPE /ID# 165577

location_facility: Asahikawa Medical University Hospital /ID# 164324

location_facility: Hospital Garcia de Orta, EPE /ID# 165579

location_facility: Massachusetts General Hospital - Crohn's and Colitis Center /ID# 164257

location_facility: Hospital Universitario Virgen Macarena /ID# 159969

location_facility: UOC Medicina Interna e Gastroe /ID# 155624

location_facility: Hokkaido P.W.F.A.C. Sapporo-Kosei General Hospital /ID# 164215

location_facility: Clinical Associates in Research Therapeutics of America, LLC /ID# 161364

location_facility: Clinical Research Center, Faculty of Medicine, Alexandria university. /ID# 201824

location_facility: Tongji Hospital Tongji Medical College of HUST /ID# 211069

location_facility: Hanyang University Gurihospital /ID# 158661

location_facility: CHU UCL Namur - site Godinne /ID# 200259

location_facility: ASST Rhodense/Presidio Ospedaliero di Rho /ID# 211450

location_facility: Theageneio Anticancer Hospital /ID# 165329

location_facility: University of Michigan Comprehensive Cancer Center Michigan Medicine /ID# 159430

location_facility: Baylor College of Medicine - Baylor Medical Center /ID# 158230

location_facility: Universitair Ziekenhuis Leuven /ID# 170829

location_facility: Azienda Ospedaliero-Universitaria Policlinico Umberto I /ID# 171223

location_facility: National Hospital Organization Hirosaki General Medical Center /ID# 164216

location_facility: Hospital Universitario San Vic /ID# 171488

location_facility: University Clinical Center Serbia /ID# 200153

location_facility: Tangdu Hospital of The Fourth Military Medical University, PLA /ID# 215505

location_facility: Sahlgrenska University Hospital Molndal /ID# 202841

location_facility: Houma Digestive Health Special /ID# 158377

location_facility: Faculdade de Medicina do ABC /ID# 163993

location_facility: Cabinet Particular Policlinic Algomed /ID# 171260

location_facility: Sapporo Higashi Tokushukai Hospital /ID# 208493

location_facility: The Catholic University of Korea, ST. Vincent's Hospital /ID# 158664

location_facility: London Health Sciences Center- University Hospital /ID# 169117

location_facility: Taipei Veterans General Hosp /ID# 171436

location_facility: Tokai University Hachioji Hospital /ID# 227102

location_facility: Renmin Hospital of Wuhan University /ID# 212867

location_facility: The Sixth Affiliated Hosp Sun /ID# 211229

location_facility: Centro Hospitalar Universitário do Algarve, EPE - Hospital de Portimão /ID# 166563

location_facility: Servicio de Salud Araucanía Norte Hospital Victoria /ID# 213152

location_facility: CHU Montpellier - Hôpital Saint Eloi /ID# 223781

location_facility: China Medical University Hospital /ID# 160194

location_facility: Nara Medical University Hospital /ID# 169222

location_facility: The First Hospital of Jilin University /ID# 212277

location_facility: Marmara Universitesi Pendik Egitim ve Arastirma Hastanesi /ID# 171290

location_facility: Hepato-Gastroenterologie HK, s.r.o. /ID# 163389

location_facility: Liverpool University Hospitals NHS Foundation Trust /ID# 203860

location_facility: Peak Gastroenterology Associates, PC /ID# 165838

location_facility: Taichung Veterans General Hospital /ID# 171433

location_facility: Renji Hospital, Shanghai Jiaotong University School of Medicine /ID# 211230

location_facility: Texas Digestive Disease Consultants /ID# 209951

location_facility: Universitatsklinikum Mannheim /ID# 162039

location_facility: Pauls Stradins Clinical University Hospital /ID# 160205

location_facility: The Second Xiangya Hospital of Central South University /ID# 211196

location_facility: Clinical Research Trials of Florida, Inc. /ID# 201794

location_facility: Cliniques Universitaires de Bruxelles Hopital Erasme /ID# 200256

location_facility: General Hospital of Ningxia Medical University /ID# 213912

location_facility: Ordensklinikum Linz GmbH Barmherzige Schwestern /ID# 216043

location_facility: CNE Regional Clinical Hospital of Ivano-Frankivsk RC /ID# 203366

location_facility: The second Affiliated hospital of Zhejiang University school of Medicine /ID# 211024

location_facility: Odense Universitets Hospital /ID# 209502

location_facility: Duplicate_Universitaetsklinikum St.Poelten /ID# 169049

location_facility: Aichi Medical University Hospital /ID# 164227

location_facility: Nemocnice Ceske Budejovice a.s. /ID# 225228

location_facility: Uludag University Medical Faculty /ID# 204179

location_facility: Air Force Specialized Hospital /ID# 170984

location_facility: Hospital Arquitecto Marcide - Complejo Hospitalario Universitario de Ferrol /ID# 159463

location_facility: Gastroenterology Group Naples /ID# 165210

location_facility: National Hospital Organization Takasaki General Medical Center /ID# 164312

location_facility: South Florida Research Ph I-IV, Inc. /ID# 161844

location_facility: Hospital of Lithuanian University of Health Sciences Kaunas Clinics /ID# 201142

location_facility: Sjællands Universitetshospital /ID# 200073

location_facility: The Newcastle Upon Tyne Hospitals NHS Foundation Trust /ID# 158047

location_facility: The First Affiliated Hospital of Nanchang University /ID# 212182

location_facility: Klinicki bolnicki centar Osijek /ID# 157595

location_facility: Centro Hospitalar de Entre Douro e Vouga /ID# 166048

location_facility: CHU de SAINT ETIENNE - Hopital Nord /ID# 207882

location_facility: Hospital Universitario Miguel Servet /ID# 159468

location_facility: Hospital das Clinicas da Faculdade de Medicina de Ribeirao Preto - USP /ID# 157668

location_facility: Panstwowy Instytut Medyczny MSWiA w Warszawie /ID# 170286

location_facility: Inje University Haeundae Hospital /ID# 203027

location_facility: General Hospital of Athens Evaggelismos and Ophthalmiatrio of Athens Polyclinic /ID# 217479

location_facility: Tyler Research Institute, LLC /ID# 166799

location_facility: Narodowy Instytut Onkologii im. Marii Skłodowskiej-Curie Panstwowy Instytut Bada /ID# 170285

location_facility: Hospital Privado Univesitario /ID# 167802

location_facility: Kitasato University Kitasato Institute Hospital /ID# 164222

location_facility: Klinicki bolnicki centar Zagreb /ID# 201915

location_facility: Hyogo Medical University Hospital /ID# 164238

location_facility: Penn State Milton S. Hershey Medical Center /ID# 230474

location_facility: Azienda Ospedaliera San Camillo Forlanini /ID# 155628

location_facility: Gastroenterology Consultants of Southwest Virginia /ID# 218142

location_facility: Klinicki bolnicki centar Split /ID# 157596

location_facility: Digestive Disease Associates, LTD /ID# 232406

location_facility: CNPE of Kyiv Regional Council Kyiv Regional Hospital /ID# 224344

location_facility: Yokkaichi Hazu Medical Center /ID# 164316

location_facility: Erciyes University Medical Fac /ID# 171283

location_facility: International Medical Center SOGAZ /ID# 206832

location_facility: Hospital Universitario de Salamanca /ID# 159469

location_facility: DiGiovanna Institute for Medical Education & Research /ID# 171128

location_facility: Medical Research Center of CT /ID# 160287

location_facility: Shengjing Hospital of China Medical University /ID# 211643

location_facility: Private Practice Dr MN Rajabally /ID# 171141

location_facility: Praxis fuer Gastroenterologie /ID# 166154

location_facility: CIUSSS de l'est de l'Ile-de-Montreal - Hopital Maisonneuve-Rosemont /ID# 169122

location_facility: Hospital Universitario Reina Sofia /ID# 167062

location_facility: Charite Universitaetsklinikum Berlin - Campus Benjamin Franklin /ID# 210508

location_facility: Caprock Gastro Research, LLC /ID# 215433

location_facility: Linkou Chang Gung Memorial Hospital /ID# 222878

location_facility: Medizinische Universitaet Graz /ID# 169052

location_facility: Rocky Mountain Pediatric Gastroenterology /ID# 207173

location_facility: LMU Klinikum Campus Grosshadern /ID# 210484

location_facility: Huai'an First People's Hospital /ID# 239197

location_facility: Complejo Asistencial Dr. Sotero del Rio /ID# 169386

location_facility: Immanuel Kant Baltic Federal University /ID# 204920

location_facility: Percuro Clinical Research, Ltd /ID# 169123

location_facility: King's College Hospital NHS Foundation Trust /ID# 158762

location_facility: Wakayama Medical University Hospital /ID# 169485

location_facility: GBUZ Allergology and Immunology Center of Ministry of Health of Kabardino-Bal /ID# 233974

location_facility: Cotton O'Neil Clinical Research Center, Digestive Health /ID# 160367

location_facility: Sisli Etfal Train & Res Hosp /ID# 171415

location_facility: St George's University Hospitals NHS Foundation Trust /ID# 208379

location_facility: Shiga University of Medical Science Hospital /ID# 164323

location_facility: Duplicate_Centrul Medical Tuculanu SRL /ID# 171263

location_facility: DM Clinical Research/Southwest /ID# 165009

location_facility: H-T. Centrum Medyczne - Endoterapia /ID# 231501

location_facility: WIP Warsaw IBD Point Profesor Kierkus /ID# 216103

location_facility: CHU Bordeaux - Hopital Haut Leveque /ID# 207883

location_facility: Hoag Memorial Hosp Presbyterian /ID# 218347

location_facility: Robley Rex VA Medical Center /ID# 218647

location_facility: VA Caribbean Healthcare System /ID# 222779

location_facility: The University of Chicago Medical Center /ID# 160511

location_facility: Hospital Clinic de Barcelona /ID# 159462

location_facility: Ulyanovsk Regional Clinical Hospital /ID# 204923

location_facility: Chu de Nice-Hopital L'Archet Ii /Id# 207881

location_facility: Hospital Alvaro Cunqueiro CHUVI /ID# 167359

location_facility: Quality Clinical Research Inc. /ID# 167312

location_facility: Atrium Health Carolinas Medical Center /ID# 158543

location_facility: St.Luke's International Hospital /ID# 225969

location_facility: Lenus Research & Medical Group /ID# 169727

location_facility: Interdisctrict Multidisciplinary Hospital /ID# 204921

location_facility: Agaplesion Markus Krankenhaus /ID# 159375

location_facility: Vanderbilt University Medical Center /ID# 160567

location_facility: General Hospital of Nikaia-Piraeus "Agios Panteleimon" /ID# 165313

location_facility: Kuzbass Regional Clinical Hospital /ID# 165759

location_facility: Barnsley Hospital NHS Foundation Trust /ID# 202771

location_facility: MVZ fuer Gastroenterlogie am Bayerischen Platz /ID# 159380

location_facility: Great Lakes Gastroenterology Research, LLC /ID# 201778

location_facility: Universitaetsklinikum Erlangen /ID# 159373

location_facility: Gokeikai Ofuna Chuo Hospital /ID# 169296

location_facility: Ctr for Advanced Gastroenterol /ID# 202820

location_facility: CHU Amiens-Picardie Site Sud /ID# 207880

location_facility: Consorci Corporacio Sanitaria Parc Tauli Sabadell /ID# 159473

location_facility: Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty /ID# 167202

location_facility: Inselspital, Universitätsspital Bern /ID# 202909

location_facility: Cleveland Clinic Main Campus /ID# 209235

location_facility: University of Rochester Medical Center /ID# 161660

location_facility: The Catholic University of Korea, Daejeon St.Mary's Hospital /ID# 242379

location_facility: UMHAT Tsaritsa Joanna - ISUL /ID# 209978

location_facility: Hospital Universitario La Paz /ID# 159471

location_facility: South Lake Pain Institute, Inc /ID# 162859

location_facility: University General Hospital of Heraklion PA.G.N.I /ID# 165327

location_facility: Clinical Hosp Center Zvezdara /ID# 200150

location_facility: Digestive Disease Specialists /ID# 170777

location_facility: Saiseikai Fukuoka Genaral Hospital /ID# 225640

location_facility: CHRU Nancy - Hopitaux de Brabois /ID# 207877

location_facility: Kyiv Municipal Clinical Hospital #18 /ID# 224347

location_facility: Instituto Goiano de Gastroenterologia e Endoscopia Digestiva /ID# 157683

location_facility: Southern Star Research Institute, LLC /ID# 168774

location_facility: Complejo Hospitalario Universitario de Pontevedra /ID# 216183

location_facility: Kaiser Clinica e Hospital Dia /ID# 157686

location_facility: Plains Clinical Research Center, LLC /ID# 169729

location_facility: General Hospital of Athens Ippokratio /ID# 229190

location_facility: A.O. Per L'Emergenza Cannizzaro /ID# 164039

location_facility: CHA University Bundang Medical Center /ID# 158669

location_facility: Azienda Ospedaliero-Universitaria di Modena /ID# 201818

location_facility: The First Affiliated Hospital of Anhui Medical University /ID# 211227

location_facility: Centro Hospitalar e Universitario de Coimbra, EPE /ID# 166050

location_facility: Vilnius University Hospital Santaros Klinikos /ID# 201144

location_facility: The Jikei University Hospital /ID# 164279

location_facility: Gastroenterologie Opernstrasse /ID# 163690

location_facility: East Tennessee Research Institute /ID# 168744

location_facility: General Hospital of Chest Diseases of Athens SOTIRIA /ID# 170910

location_facility: Perm Clinical Center of the Federal Medical and Biological Agency /ID# 227456

location_facility: Bispebjerg and Frederiksberg Hospital /ID# 208953

location_facility: The Chaim Sheba Medical Center /ID# 211279

location_facility: Colo-proctology Center Matsushima Clinic /ID# 225915

location_facility: Yale Univ Digestive Diseases /ID# 213265

location_facility: Stadtisches Klinikum Braunschweig /ID# 163694

location_facility: Hospital de Clinicas de Porto Alegre /ID# 157670

location_facility: Adult Gastroenterology Associates - Gen 1 Research /ID# 208873

location_facility: Chung Shan Medical University Hospital /ID# 171426

location_facility: Fujita Health University Hospital /ID# 164313

location_facility: Fondazione Policlinico Universitario Campus Bio-Medico di Roma /ID# 163994

location_facility: Sapporo Medical University Hospital /ID# 164278

location_facility: Ospedale Sant Orsola Malpighi /ID# 155627

location_facility: Columbia Univ Medical Center /ID# 161929

location_facility: Hospital da Senhora da Oliveira Guimaraes, EPE /ID# 165576

location_facility: Hospital Universitario de Cabuenes /ID# 170745

location_facility: Clinic of New Technologies of Medicine /ID# 204926

location_facility: Ruijin Hospital, Shanghai Jiaotong University School of Medicine /ID# 210960

location_facility: Yamagata University Hospital /ID# 171481

location_facility: Unidad de Atencion Medica e Investigacion en Salud /ID# 206515

location_facility: KL Ling Gastroenterology and Liver Clinic /ID# 206563

location_facility: Yeungnam University Medical Center /ID# 158662

location_facility: Scott Shulman Medicine Professional Corporation /ID# 169127

location_facility: Nagasaki University Hospital /ID# 205326

location_facility: Praxiszentrum fuer Gastroenterologie /ID# 219072

location_facility: First Moscow State Medical University n.a I.M. Sechenov /ID# 204981

location_facility: Advanced Research Institute, Inc /ID# 161945

location_facility: Clin Hosp Ctr Bezanijska Kosa /ID# 202060

location_facility: Southern California Res. Ctr. /ID# 169659

location_facility: Yonsei University Health System Severance Hospital /ID# 158660

location_facility: Kanazawa University Hospital /ID# 169221

location_facility: Regional Clinical Hospital #1 /ID# 165763

location_facility: Montreal General Hospital- McGill University Health Center /ID# 169118

location_facility: Soroka University Medical Center /ID# 171093

location_facility: West China Hospital, Sichuan University /ID# 211275

location_facility: University Hospital Southampton NHS Foundation Trust /ID# 210814

location_facility: Centex Studies, Inc. - Houston /ID# 201221

location_facility: Inonu Universitesi Turgut Ozal /ID# 203980

location_facility: The Second Hospital of Hebei Medical University /ID# 213019

location_facility: Pusan National University Hospital /ID# 158670

location_facility: Tokyo Medical And Dental University Hospital /ID# 164225

location_facility: Hospital Guillermo Grant Benavente de Concepción /ID# 210762

location_facility: National Medical Research Center of Coloproctology n.a. A. N. Ryzhikh /ID# 203513

location_facility: Health Pharma Professional Research S.A de C.V /ID# 206516

location_facility: Tzaneio general hospital of Piraeus /ID# 206437

location_facility: Hadassah Medical Center-Hebrew University /ID# 171092

location_facility: Vitamed Galaj i Cichomski Sp.j. /ID# 213358

location_facility: Sir Run Run Shaw Hospital,Meical School Zhejiang University /ID# 211062

location_facility: Centro Hosp de Tondela-Viseu /ID# 166049

location_facility: Ponce Medical School Foundation /ID# 222825

location_facility: Cedars-Sinai Medical Center-West Hollywood /ID# 163848

location_facility: Gastro Health & Nutrition - Victoria /ID# 164308

location_facility: ASST Fatebenefratelli Sacco-Ospedale Sacco /ID# 155623

location_facility: Kitasato University Hospital /ID# 169223

location_facility: Allen Whey Khye Lim Professional Corporation /ID# 169770

location_facility: Azienda Ospedaliera Universitaria Policlinico Tor Vergata /ID# 158020

location_facility: Clinical Research Center, Faculty of Medicine, Alexandria university. /ID# 226795

location_facility: Louisiana Research Center, LLC /ID# 201205

location_facility: ProMedica Physicians Digestive Healthcare /ID# 215622

location_facility: Baylor Scott & White Center for Diagnostic Medicine /ID# 204132

location_facility: Medizinische Universitaet Wien /ID# 169051

location_facility: Hospital Provincial del Centenario /ID# 170896

location_facility: Clinical Research Center, Faculty of Medicine, Alexandria university. /ID# 226796

location_facility: General Hospital of Athens Laiko /ID# 206438

location_facility: Ospedale Policlinico San Martino /ID# 164030

location_facility: Clin Res Inst of Michigan, LLC /ID# 160300

location_facility: Centre Médico Chirurgical Ambroise Paré Hartmann /ID# 249861

location_facility: IRCCS Ospedale Sacro Cuore Don Calabria /ID# 164029

location_facility: Fırat University Medical Facul /ID# 171285

location_facility: Nagoya City University Hospital /ID# 164229

location_facility: Osaka Medical and Pharmaceutical University Hospital /ID# 226036

location_facility: Cambridge University Hospitals NHS Foundation Trust /ID# 158046

location_facility: Gastrointestinal Biosciences Clinical Trials, LLC /ID# 200934

location_facility: Gastroenterology Associates, P.A. of Greenville /ID# 160457

location_facility: Klinicki bolnicki centar Zagreb /ID# 157594

location_facility: Landeskrankenhaus Salzburg-Universitätsklinikum der PMU (LKH) /ID# 200686

location_facility: Kobenhavns Universitet - Hvidovre Hospital (HH) /ID# 205093

location_facility: Virginia Mason Medical Center /ID# 160432

location_facility: Toronto Digestive Disease Associates, Inc. /ID# 169120

location_facility: Fakultna nemocnica s poliklinikou Nove Zamky /ID# 224100

location_facility: Wellington Regional Hospital /ID# 205338

location_facility: Showa University Fujigaoka Hospital /ID# 209606

location_facility: Universitaetsklinikum Regensburg /ID# 163693

location_facility: Hospital Nossa Senhora das Graças /ID# 157677

location_facility: Gastroenterologische Gemeinschaftspraxis Minden /ID# 162037

location_facility: St. Marianna University Hospital /ID# 226730

location_facility: Hamamatsu University Hospital /ID# 226729

location_facility: Gastroenterology Associates of Central Georgia, LLC /ID# 160513

location_facility: National Taiwan University Hospital /ID# 162188

location_facility: Hiroshima University Hospital /ID# 164240

location_facility: Groupe Sante CHC - Clinique du MontLegia /ID# 200255

location_facility: Royal Devon University Healthcare NHS Foundation Trust /ID# 157614

location_facility: Fukuoka University Chikushi Hospital /ID# 209056

location_facility: Toho University Sakura Medical Center /ID# 164219

location_facility: Hospital Universitario Puerta de Hierro, Majadahonda /ID# 159466

location_facility: ASST Grande Ospedale Metropolitano Niguarda /ID# 170959

location_facility: Fakultni nemocnice u sv. Anny v Brne /ID# 239158

location_facility: Union Hospital affiliated to Tongji Medical College of Huazhong University of Sc /ID# 211070

location_facility: Japanese Red Cross Wakayama Medical Center /ID# 171196

location_facility: Central Clinical Hospital RZHD Medicine /ID# 204922

location_facility: Municipal Nonprofit Enterprise Kherson city clinical hospital n.a. Y.Y. Karabel /ID# 224349

location_facility: UCSF Center for Colitis and Crohn's Disease /ID# 201209

status: Active, not recruiting

title: A Multicenter, Randomized, Double-Blind, Placebo Controlled 52-Week Maintenance and an Open-Label Extension Study of the Efficacy and Safety of Risankizumab in Subjects With Ulcerative Colitis

primary_purpose: Treatment

type: EudraCT Number

type: Other Identifier

source: euctr

enrollment_type: Actual

design_allocation: Randomized

study_completion_date_type: Anticipated

location_country:
Germany
Poland
New Zealand
Argentina
Japan
Brazil
Turkey
Croatia
Chile
Czechia
Canada
Serbia
France
Slovenia
Lithuania
Colombia
Portugal
Slovakia
Denmark
Switzerland
United States
Latvia
Ukraine
Romania
Belgium
China
Puerto Rico
Egypt
Italy
United Kingdom
Singapore
Sweden
Netherlands
Austria
Mexico
Korea, Republic of
Spain
Greece
South Africa
Taiwan
Bulgaria
Russian Federation
Israel

study_type: Interventional

ipd_sharing: Yes

lead_sponsor_type: industriel

status_simplified: Ongoing


title: TIGER-3: A Phase 3, Open-label, Multicenter, Randomized Study of Oral Rociletinib (CO-1686) Monotherapy Versus Single-agent Cytotoxic Chemotherapy in Patients With Mutant EGFR Non-small Cell Lung Cancer (NSCLC) After Failure of at Least 1 Previous EGFR-directed Tyrosine Kinase Inhibitor (TKI) and Platinum-doublet Chemotherapy

summary: The purpose of this study is to compare the anti-tumor efficacy of oral single-agent rociletinib, as measured by investigator assessment of the PFS, with that of single-agent cytotoxic chemotherapy in patients with EGFR-mutated, advanced/metastatic NSCLC after failure of at least 1 previous EGFR-directed TKI and at least 1 line of platinum-containing doublet chemotherapy.

status: Terminated

study_completion_date_type: Actual

lead_sponsor: Clovis Oncology, Inc.

location_country:
Germany
Italy
United Kingdom
Australia
Netherlands
United States
Korea, Republic of
Spain
Taiwan
France

location_facility: IRCCS Azienda Ospedaliera Universitaria San Martino - IST

location_facility: University of Texas Southwestern Medical Center

location_facility: The Catholic University of Korea Saint Vincent's Hospital

location_facility: Centre Hospitalier Universitaire de Rennes, Hôpital Pontchaillou

location_facility: Centre Hospitalier Intercommunal Créteil

location_facility: Walter Reed National Military Medical Center

location_facility: Oregon Health & Science University (OHSU) - Knight Cancer Institute

location_facility: Cancer Care Associates Medical Group, Inc.

location_facility: Hospital Universitari Germans Trias i Pujol

location_facility: Hospital Regional Universitario Carlos Haya

location_facility: Sylvester Comprehensive Cancer Center (UMHC)

location_facility: University of California San Diego Moores Cancer Center

location_facility: Seoul National University Bundang Hospital

location_facility: Chonnam National University Hwasun Hospital

location_facility: Guy's and Saint Thomas NHS Foundation Trust

location_facility: L'Assistance Publique - Hopitaux de Marseille

location_facility: The Oncology Institute of Hope and Innovation

location_facility: University of Pittsburgh Cancer Institute (UPMC)

location_facility: The Ohio State University Comprehensive Cancer Center

location_facility: Central Coast Medical Oncology Corporation

location_facility: University of California, San Francisco Helen Diller Family Comprehensive Cancer Center

location_facility: University of Florida Health Science Center

location_facility: Fundacion Jimenez Diaz (Clinica de la Concepcion) (UAM -FJD)

status_simplified: Unknown


lead_sponsor: pharmaand GmbH

summary: Patients enrolled into this study will be stratified into 3 groups based on gene mutations identified in their tumor tissue. The purpose of this study is to evaluate patient response to maintenance treatment with rucaparib versus placebo. Response to treatment will be analyzed based on homologous recombination (HR) status of tumor samples.

ReferenceType: derived

ReferenceCitation: Green ML, Ma SC, Goble S, Giordano H, Maloney L, Simmons AD, Beltman J, Harding TC, Xiao JJ. Population pharmacokinetics of rucaparib in patients with advanced ovarian cancer or other solid tumors. Cancer Chemother Pharmacol. 2022 May;89(5):671-682. doi: 10.1007/s00280-022-04413-7. Epub 2022 Apr 10.

oa_host_type: closed

repositories_concat: closed

publisher_dissemination: Springer-Nature

ReferenceCitation: Tattersall A, Ryan N, Wiggans AJ, Rogozinska E, Morrison J. Poly(ADP-ribose) polymerase (PARP) inhibitors for the treatment of ovarian cancer. Cochrane Database Syst Rev. 2022 Feb 16;2(2):CD007929. doi: 10.1002/14651858.CD007929.pub4.

oa_host_type: repository

evidence: oa repository (via OAI-PMH title and first author match)

host_type: repository

license_normalized: no license

repository_institution: University College London - UCL Discovery

repository_normalized: UCL Discovery

version: publishedVersion

evidence: oa repository (via pmcid lookup)

repository_normalized: PubMed Central

repositories:
PubMed Central
UCL Discovery

repositories_concat: PubMed Central;UCL Discovery

unpaywall_oa_status: green

publisher_dissemination: Wiley

ReferenceCitation: Colombo N, Oza AM, Lorusso D, Aghajanian C, Oaknin A, Dean A, Weberpals JI, Clamp AR, Scambia G, Leary A, Holloway RW, Gancedo MA, Fong PC, Goh JC, O'Malley DM, Armstrong DK, Banerjee S, Garcia-Donas J, Swisher EM, Meunier J, Cameron T, Maloney L, Goble S, Bedel J, Ledermann JA, Coleman RL. The effect of age on efficacy, safety and patient-centered outcomes with rucaparib: A post hoc exploratory analysis of ARIEL3, a phase 3, randomized, maintenance study in patients with recurrent ovarian carcinoma. Gynecol Oncol. 2020 Oct;159(1):101-111. doi: 10.1016/j.ygyno.2020.05.045. Epub 2020 Aug 26.

oa_colors: green hybrid

oa_host_type: publisher;repository

evidence: open (via crossref license)

host_type: publisher

license: cc-by-nc-nd

license_normalized: cc-by-nc-nd

evidence: oa repository (via OAI-PMH doi match)

repository_institution: PubMed Central - Europe PMC

version: acceptedVersion

unpaywall_oa_status: hybrid

publisher_dissemination: Elsevier

ReferenceCitation: Ledermann JA, Oza AM, Lorusso D, Aghajanian C, Oaknin A, Dean A, Colombo N, Weberpals JI, Clamp AR, Scambia G, Leary A, Holloway RW, Gancedo MA, Fong PC, Goh JC, O'Malley DM, Armstrong DK, Banerjee S, Garcia-Donas J, Swisher EM, Cameron T, Maloney L, Goble S, Coleman RL. Rucaparib for patients with platinum-sensitive, recurrent ovarian carcinoma (ARIEL3): post-progression outcomes and updated safety results from a randomised, placebo-controlled, phase 3 trial. Lancet Oncol. 2020 May;21(5):710-722. doi: 10.1016/S1470-2045(20)30061-9.

version: submittedVersion

ReferenceCitation: Coleman RL, Oza AM, Lorusso D, Aghajanian C, Oaknin A, Dean A, Colombo N, Weberpals JI, Clamp A, Scambia G, Leary A, Holloway RW, Gancedo MA, Fong PC, Goh JC, O'Malley DM, Armstrong DK, Garcia-Donas J, Swisher EM, Floquet A, Konecny GE, McNeish IA, Scott CL, Cameron T, Maloney L, Isaacson J, Goble S, Grace C, Harding TC, Raponi M, Sun J, Lin KK, Giordano H, Ledermann JA; ARIEL3 investigators. Rucaparib maintenance treatment for recurrent ovarian carcinoma after response to platinum therapy (ARIEL3): a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet. 2017 Oct 28;390(10106):1949-1961. doi: 10.1016/S0140-6736(17)32440-6. Epub 2017 Sep 12. Erratum In: Lancet. 2017 Oct 28;390(10106):1948.

oa_colors: green other

evidence: open (via crossref license, author manuscript)

license: publisher-specific-oa

license_normalized: publisher-specific

repository_institution: The University of Glasgow - Enlighten: Publications

repository_institution: University of California - eScholarship University of California

sponsor_collaborators:
pharmaand GmbH
Foundation Medicine
Myriad Genetics, Inc.

location_facility: Hospital Regional Universitario Carlos Haya de Malaga

location_facility: The Ohio State University Wexner Medical Center

location_facility: Centre Hospitalier Universitaire de Québec

location_facility: CHUM Centre Hospitalier de l'Université de Montréal

location_facility: Istituto Nazionale Tumori IRCCS Fondazione Pascale

location_facility: Azienda Ospedaliero-Universitaria di Bologna - Policlinico S.Orsola-Malpighi

location_facility: University of California San Francisco (UCSF)

location_facility: Sir Bobby Robson Cancer trials research Centre, Northern Centre For Cancer Care

location_facility: Instituto Valencia de Oncologia-Fundacion

location_facility: Policlinico Universitario Agostino Gemelli

location_facility: Oncology Unit City Hospital degli Infermi

location_facility: Washington University School of Medicine - Division of Gynaecological Oncology

location_facility: Centro Integral Oncológico Clara Campal, Hospital de Madrid Norte-San Chinarro

location_facility: Hospital Clinico Universitario de Valencia

location_facility: Karmanos Cancer Institute - Wayne State University

location_facility: Azienda Ospedaliero Universitaria Policlinico di Modena

location_facility: Fondazione IRCCS National Cancer Institute

location_facility: University of Texas MD Anderson Cancer Center

location_facility: Dr. Horst Schmidt Klinik, Klinik fuer Gynaekologie und Gyn. Onkologie

location_facility: University of California Los Angeles (UCLA)

location_facility: Oncology Institute, Sheba Medical Center

title: A Study of Rucaparib as Switch Maintenance Following Platinum-Based Chemotherapy in Patients With Platinum-Sensitive, High-Grade Serous or Endometrioid Epithelial Ovarian, Primary Peritoneal or Fallopian Tube Cancer ( ARIEL3 )

location_country:
Germany
Italy
New Zealand
Israel
United Kingdom
Australia
Belgium
United States
Spain
Canada
France


title: A Phase 2 Dose Ranging, Randomized, Double Blind, Placebo-Controlled Study Evaluating the Safety, Tolerability, Pharmacokinetics and Efficacy of EDP-305 in Subjects With Primary Biliary Cholangitis (PBC) With or Without an Inadequate Response to Ursodeoxycholic Acid (UDCA)

summary: A randomized, double-blind study to assess the safety, tolerability, PK and efficacy of EDP-305 in subjects with primary biliary cholangitis

status: Completed

ipd_sharing: No

lead_sponsor: Enanta Pharmaceuticals, Inc

sponsor_collaborators:
Enanta Pharmaceuticals, Inc
Pharmaceutical Research Associates
Triangle Biostatistics

location_country:
Germany
United Kingdom
Australia
Netherlands
Austria
Belgium
United States
Spain
Canada
France

location_facility: Norfolk and Norwich University Hospitals NHS Foundation Trust

location_facility: University of Pittsburgh Medical Center - Center for Liver Disease

location_facility: Digestive Health Specialists of the Southeast

location_facility: London Health Sciences Centre University Hospital

location_facility: University Hospitals Birmingham NHS Foundation Trust

location_facility: Hospital Universitari i Politecnic La Fe de Valencia

location_facility: Centre Hospitalier Universitaire Amines-Picardie Hôpital Sud

location_facility: Hospital Universitario Marqués de Valdecilla

location_facility: King's College Hospital NHS Foundation Trust

location_facility: Cambridge University Hospitals NHS Foundation Trust

location_facility: The Liver Institute at Methodist Dallas Medical Center

location_facility: American Research Corporation at the Texas Liver Institute

location_facility: South Denver Gastroenterology - Swedish Medical Center Office

location_facility: Universidad de Valladolid - Hospital Universitario Rio Hortega

location_facility: Centre Hospitalier Régional Universitaire de Lille

location_facility: University of Miami Leonard M. Miller School of Medicine

location_facility: University of Iowa Hospitals and Clinics

location_facility: Universitaetsmedizin der Johannes Gutenberg-Universitaet Mainz

location_facility: Hospital Universitario Virgen de la Arrixaca

location_facility: Gastroenterology Consultants of Clearwater

status_simplified: Completed


title: An Open-Label, Phase 2b, Global Multicenter Cohort Trial to Assess the Safety and Efficacy of Zipalertinib in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer With Exon 20 Insertion and Uncommon/Single or Compound Epidermal Growth Factor Receptor Mutations.

summary: The purpose of this study is to evaluate the safety and efficacy of zipalertinib in patients with locally advanced or metastatic NSCLC harboring EGFR ex20ins mutations and other mutations.

status: Recruiting

design_allocation: Non-Randomized

enrollment_type: Anticipated

lead_sponsor: Taiho Oncology, Inc.

location_country:
Germany
Italy
United Kingdom
Hong Kong
Australia
Japan
United States
Korea, Republic of
Spain
Turkey
Canada
France

location_facility: T.C. Saglik Bakanligi Adana Sehir Egitim ve Arastirma Hastanesi

location_facility: Trakya Üniversitesi Saglik Arastirma ve Uygulama Merkezi

location_facility: William Osler Health System - Brampton Civic Hospital

location_facility: Azienda Ospedaliero - Universitaria Careggi

location_facility: Complejo Hospitalario Universitario A Coruña

location_facility: Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) - Ospedale San Raffaele

location_facility: Institut Català d'Oncologia - Hospital Duran i Reynals (ICO L'Hospitalet)

location_facility: Azienda Ospedaliero-Universitaria di Parma

location_facility: Azienda Ospedaliero - Universitaria di Modena

location_facility: Froedtert and Medical College of Wisconsin

location_facility: Catholic University of Korea Saint Vincent's Hospital

location_facility: O'Neal Comprehensive Cancer Center at the University of Alabama at Birmingham

location_facility: T.C. Saglik Bakanligi Ankara Bilkent Sehi?r Hastanesi?

location_facility: Centre Hospitalier Universitaire Limoges

location_facility: Memorial Sloan Kettering Cancer Center - New York

location_facility: SCRI - Mark H. Zangmeister Cancer Center

location_facility: Universitätsklinikum Gießen und Marburg - Gießen

location_facility: Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) - Ospedale Policlinico San Martino

location_facility: Tennessee Oncology - Nashville - Centennial Clinic - Medical Oncology

location_facility: Azienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare Arrigo - Alessandria

location_facility: Universitatsklinikum Carl Gustav Carus Dresden

location_facility: Bagcilar Medipol Mega Universite Hastanesi

location_facility: Azienda Ospedaliero-Universitaria di Bologna - Policlinico Sant Orsola-Malpighi

location_facility: Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori" - IRST

location_facility: Ankara Il Saglik Mudurlugu SBU Gulhane Egitim Ve Arastirma Hastanesi

location_facility: Les Hôpitaux Universitaires de Strasbourg

location_facility: Hospital Regional Universitario de Málaga - Hospital General

location_facility: Virginia Cancer Specialists - Fairfax Office

location_facility: Seoul National University Bundang Hospital

location_facility: Chonnam National University Hwasun Hospital

location_facility: Azienda Ospedaliera Universitaria - Università degli Studi della Campania Luigi Vanvitelli

location_facility: The Clatterbridge Cancer Centre NHS Foundation Trust

location_facility: Istinye Üniversite Hastanesi Liv Hospital Bahcesehir

location_facility: Torbay and South Devon NHS Foundation Trust

location_facility: Azienda Ospedaliero Universitaria Policlinico Gaspare Rodolico - San Marco

location_facility: Azienda Unità Sanitaria Locale della Romagna

location_facility: Centre Hospitalier Universitaire De Nantes - Hôpital Nord Laennec

location_facility: Azienda Unità Sanitaria Locale - Piacenza

location_facility: Comprehensive Cancer Centers of Nevada - Horizon Ridge Henderson

location_facility: T.C. Saglik Bakanligi - Istanbul Il Saglik Mudurlugu - Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi

location_facility: The Catholic University of Korea - Seoul St. Mary's Hospital

location_facility: Hospital Universitario Fundación Jiménez Díaz

location_facility: Nottingham University Hospitals NHS Trust


title: A Randomized Phase 3 Study of MRTX849 in Combination With Cetuximab Versus Chemotherapy in Patients With Advanced Colorectal Cancer With KRAS G12C Mutation With Disease Progression On or After Standard First-Line Therapy

summary: Study 849-010 is an open-label, randomized Phase 3 clinical trial comparing the efficacy of MRTX849 administered in combination with cetuximab versus chemotherapy in the second-line treatment setting in patients with CRC with KRAS G12C mutation.

lead_sponsor: Mirati Therapeutics Inc.

location_country:
Finland
Germany
Ireland
Poland
Argentina
Australia
Brazil
Thailand
Czechia
Canada
France
Colombia
Portugal
Hong Kong
Denmark
United States
Romania
Belgium
China
Malaysia
Puerto Rico
Italy
United Kingdom
Singapore
Netherlands
Austria
Mexico
Korea, Republic of
Spain
Greece
Taiwan


title: Upadacitinib Treatment Patterns, Achievement of Treatment Targets and Maintenance of Response in Moderate to Severe Rheumatoid Arthritis Patients in Real-World Practice (UPHOLD)

acronym: UPHOLD

summary:
Rheumatoid Arthritis (RA) is an inflammatory disease of the joints causing pain, stiffness, swelling and loss of joint function. Despite the range of treatment options for RA steadily increasing, many patients remain sub-optimally managed, with sustained clinical remission rarely achieved. This study will assess the treatment patterns, achievement of treatment targets and maintenance of response.

Upadacitinib is a drug approved for the treatment of moderately to severely active rheumatoid arthritis. Adult participants with moderate to severe RA who have been prescribed upadacitinib by their physicians will be enrolled. Approximately, 1660 participants will be enrolled this study, worldwide.

Participants will not receive Upadacitinib as part of this study, but will be followed for response to treatment for up to 24 months.

There may be higher burden for participants in this trial compared to their standard of care. Participants will attend regular visits, every 3 months, during the course of the study at a hospital or clinic and will be asked to provide additional information by questionnaire at each visit.

study_type: Observational

time_perspective: Prospective

ipd_sharing: Undecided

location_country:
Germany
Ireland
Argentina
Australia
Kuwait
France
Switzerland
Belgium
Italy
Austria
Mexico
United Arab Emirates
Uruguay
Saudi Arabia
Spain
Greece
Taiwan
Russian Federation
Israel

location_facility: Nebbiolo Clinical Research Center /ID# 224900

location_facility: Voronezh State Medical Univers /ID# 224854

location_facility: Hospital Universitario Virgen de las Nieves /ID# 231841

location_facility: China Medical University Hospital /ID# 241051

location_facility: AOU Universita degli Studi della Campania Luigi Vanvitelli /ID# 229057

location_facility: Hospital Parc de Salut del Mar /ID# 240000

location_facility: Azienda Ospedaliero-Universitaria di Modena /ID# 228554

location_facility: Ulyanovsk Regional Clinical Hospital /ID# 239164

location_facility: CH La Rochelle - Hopital Saint Louis /ID# 224240

location_facility: CH Cannes - les Broussailles /ID# 226160

location_facility: Azienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare Arrigo /ID# 228889

location_facility: Azienda Ospedaliero Universitaria Ospedali Riuniti di Ancona /ID# 229440

location_facility: Hospital Universitario Virgen del Rocio /ID# 231836

location_facility: Centre Hospitalier de CHOLET /ID# 222455

location_facility: Azienda Ospedaliera Universitaria Friuli Centrale/Presidio Ospedaliero Universit /ID# 228551

location_facility: Praxis fuer Rheumatologie und Innere Medizin /ID# 225222

location_facility: General Hospital of Thessaloniki Hippokrateio /ID# 229965

location_facility: Hospital Universitario Mutua Terrassa /ID# 231822

location_facility: CHU Grenoble - Hopital Michallon /ID# 223211

location_facility: CHU UCL Namur - site Godinne /ID# 222797

location_facility: Budgetary Institution of the Khanty-Mansiysk Autonomous Okrug-Yugra "Surgut Dist /ID# 243313

location_facility: Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII (Presidio Papa Giovanni /ID# 228967

location_facility: Klinikum Klagenfurt am Woerthersee /ID# 239628

location_facility: General Hospital of Athens Ippokratio /ID# 224164

location_facility: University General Hospital of Heraklion PA.G.N.I /ID# 224133

location_facility: Hôpital d'instruction des armées Bégin /ID# 222440

location_facility: National Taiwan University Hospital /ID# 241050

location_facility: Rheumatologische-Immunologische Praxis Templin /ID# 226924

location_facility: ASST Grande Ospedale Metropolitano Niguarda /ID# 228807

location_facility: Azienda Ospedaliero-Universitaria Sant'Andrea /ID# 227942

location_facility: Centro Especializado en Diabetes, Obesidad y Prevencion de Enfermedades Cardiova /ID# 224360

location_facility: CHD Vendée- La Roche-sur-Yon - Les Oudairies /ID# 229086

location_facility: CHU de Besancon - Jean Minjoz /ID# 222463

location_facility: CHU Toulouse - Hopital Purpan /ID# 223150

location_facility: Rheumapraxis Prof Dr Karin Manger /ID# 224086

location_facility: Saudi German Hospital Jeddah /ID# 243234

location_facility: Private Practice - Scott Walter Graf /ID# 223958

location_facility: Cabinet liberal - Compiegne - Dr Banse /ID# 227099

location_facility: Azienda Ospedaliero Universitaria Pisana-Stabilimento di Santa Chiara /ID# 228550

location_facility: Hospital Universitario A Coruna - CHUAC /ID# 231818

location_facility: Rheuma-Zentrum Wien-Oberlaa GmbH /ID# 227853

location_facility: Rheumatologisches Versorgungszentrum Weinfelden /ID# 222346

location_facility: Hospital Clinico Universitario Virgen de la Arrixaca /ID# 231847

location_facility: Cabinet de Rhumatologie Poincare /ID# 224755

location_facility: Organizacion Medica de Investigacion (OMI) /ID# 222187

location_facility: Hospital Universitario de Jaen /ID# 231842

location_facility: Cabinet Rhumatologie St Michel Sur Orge /ID# 225176

location_facility: ACURA Rheumazentrum Baden-Bade /ID# 225225

location_facility: Clinical Rheumatologic Hospital No 25 /ID# 242475

location_facility: Hospital Universitario Torrecardenas /ID# 241931

location_facility: Cabinet rhumatologie Dr NECTOUX /ID# 225828

location_facility: The Chaim Sheba Medical Center /ID# 222034

location_facility: CHU Bordeaux - Hopital Pellegrin /ID# 224837

location_facility: Fondazione IRCCS Policlinico /ID# 227937

location_facility: Hospital Universitario Virgen de la Victoria /ID# 240150

location_facility: Algemeen Stedelijk Ziekenhuis /ID# 224121

location_facility: Azienda Ospedaliera Regionale San Carlo /ID# 228648

location_facility: Hospital Ernest Lluch Martin /ID# 238779

location_facility: Helios Fachklinik Vogelsang-Gommern /ID# 222949

location_facility: GBUZ TO Regional Clinical Hospital No. 1 /ID# 241113

location_facility: CHUV, Centre hospitalier universitaire vaudois /ID# 224161

location_facility: Integrated Rheumatology and Arthritis Center /ID# 223177

location_facility: Departnent of Medicine-Rheumatology Al Baraha Hospital and Al Qasmi Hospital Min /ID# 223178

location_facility: CHU Strasbourg - Hopital de Hautepierre /ID# 222450

location_facility: CHU de Nantes, Hotel Dieu -HME /ID# 225787

location_facility: Hospital Santa Creu i Sant Pau /ID# 231821

location_facility: Groupe Médical Spécialisé - Le Premium /ID# 223719

location_facility: CHU de SAINT ETIENNE - Hopital Nord /ID# 222456

location_facility: MVZ Ambulantes Rheumazentrum Erfurt /ID# 224812

location_facility: Centro Integral en Reumatologia S.A de C.V /ID# 224363

location_facility: CHU Amiens-Picardie Site Sud /ID# 222444

location_facility: CH Bigorre - Site de la Gespe /ID# 225141

location_facility: Dres. Teipel/Toussaint/Saech /ID# 226923

location_facility: Krankenhaus der Barmherzigen Brueder Trier /ID# 226927

location_facility: Fondazione Policlinico Universitario Agostino Gemelli IRCCS-Università Cattolica /ID# 229061

location_facility: A.0.Ordine Mauriziano/Ospedale Umberto I di Torino /ID# 228888

location_facility: General Hospital of Athens Gennimatas /ID# 225064

location_facility: MVZ für Rheumatologie Dr. M. Welcker GmbH /ID# 226926

location_facility: Centre Hospitalier d'Angouleme /ID# 226064

location_facility: Cabinet libéral du Dr PAUPIERE /ID# 238723

location_facility: Eisterhues, Braunschweig, DE /ID# 225186

location_facility: University General Hospital Attikon /ID# 224136

location_facility: General Hospital of Patras Agios Andreas /ID# 224132

location_facility: Azienda Ospedaliera Universitaria Paolo Giaccone /ID# 228160

location_facility: The Lady Davis Carmel Medical Center /ID# 223851

location_facility: CHU Clermont Ferand - Hopital Gabriel Montpied /ID# 223801

location_facility: Azienda Ospedaliero-Universitaria Policlinico Umberto I /ID# 228014

location_facility: Hospital Universitario de Jerez de la Frontera /ID# 231844

location_facility: Azienda Ospedaliera Civico Di Cristina Benfratelli- P.O. Civico /ID# 228912

location_facility: Moscow Regional Research and Clinical Institute n.a. Vladimirskiy (MONIKI) /ID# 224852

location_facility: General Hospital Asklepieio Voulas /ID# 224131

location_facility: Hospital Universitario de Getafe /ID# 231825

location_facility: St Vincent's University Hospital /ID# 224200

location_facility: Hopital de la Cavale Blanche /ID# 222462

location_facility: AP-HP - Hopital Bichat - Claude-Bernard /ID# 222449

location_facility: Centre Hospitalier de Boulogne Sur Mer /ID# 222991

location_facility: Private practice Sint-Niklaas /ID# 224123

location_facility: Hospital Universitario Virgen de Valme /ID# 231838

location_facility: CINTRE, Centro de Investigación y Tratamiento Reumatológico SC /ID# 240836

location_facility: Fondazione Policlinico Universitario Campus Bio-Medico di Roma /ID# 229063

location_facility: AP-HP - Hopital Saint-Antoine /ID# 222441

location_facility: International Medical Center /ID# 243235

location_facility: CIER Centro de Investigaciones en Enfermedades Reumaticas /ID# 231769

location_facility: CHU Montpellier - Hôpital Saint Eloi /ID# 222452

location_facility: GH Diaconesses Croix Saint-Simon /ID# 229126

location_facility: Hospital Universitario Virgen Macarena /ID# 231837

location_facility: Samara Regional Clinical Hospital n.a. V. D. Seredavin /ID# 227852

location_facility: Azienda Ospedaliero-Universitaria Senese-Ospedale Santa Maria delle Scotte /ID# 227938

location_facility: Die Fachaerzte im Rottal - Nephrologie, Rheumatologie /ID# 223866

location_facility: ELSAN - Clinique du Pont de Chaume /ID# 224898

location_facility: Azienda Ospedaliera Universitaria di Verona/Ospedale Borgo Trento /ID# 228553

location_facility: Consultorio Medico Privado - Miryam Eguia Bernal /Id# 243255

location_facility: Consultorio Privado Jorge Rojas Serrano /Id# 243258

location_facility: Hospital General Universitario Santa Lucia /ID# 238780

location_facility: CHRU Tours - Hopital Trousseau /ID# 222445

location_facility: ASST Gaetano Pini/Presidio Ospedaliero Pini /ID# 228556

location_facility: Kaohsiung Medical University Chung-Ho Memorial Hospital /ID# 241052

location_facility: Azienda Ospedaliera Universitaria Consorziale Policlinico /ID# 228580

location_facility: HFR Fribourg - Hôpital cantonal /ID# 224163

location_facility: Drt Sulaiman Al Habib Hospital /ID# 226575

location_facility: cabinet liberal- Dr CORNILLE /ID# 227869

location_facility: CH Roubaix - Hopital Victor Provo /ID# 225032

location_facility: 251 Airforce General Hospital /ID# 225065

location_facility: Centro de Estudios de Investigación Básica y Clínica, S.C. /ID# 224364

location_facility: ASL 3 Genovese - Ospedale la Colletta /ID# 228892

location_facility: Nort-Western State Medical University n.a. Mechnikov /ID# 223419

location_facility: Orenburg State Medical University /ID# 243615

location_facility: CHU Montpellier - Hôpital Saint Eloi /ID# 223394

location_facility: Linkou Chang Gung Memorial Hospital /ID# 241053

location_facility: Clinica de Investigacion en Reumatologia y Obesidad S.C. /ID# 224361

location_facility: Centre Hospitalier Jean Rougie /ID# 224242

location_facility: CHR Orleans - Hopital de la Source /ID# 223591

location_facility: Centre de Soins Osteoarticulaires Ambulatoires /ID# 224737

location_facility: Hospital General de Granollers /ID# 238778

location_facility: CHU de Rennes - Hospital Sud /ID# 222458

location_facility: Azienda Ospedaliera Universitaria "San Giovanni di Dio e Ruggi d'Aragona /ID# 229065

location_facility: ASST Spedali civili di Brescia /ID# 228970

location_facility: Military Medical Academy n.a. Kirov /ID# 242351

location_facility: University General Hospital of Alexandroupolis /ID# 224880

location_facility: Tallaght University Hospital /ID# 231260

location_facility: Clinic of Samara State Medical University /ID# 241168

location_facility: Azienda Ospedaliero-Universitaria di Ferrara-Arcispedale Sant Anna /ID# 228788

location_facility: RM Pharma Specialists S.A de C.V. /ID# 224359

location_facility: King Abdulaziz University Hospital /ID# 222724

location_facility: Hospital Universitario Canarias /ID# 231848

location_facility: CHU Lille - Hôpital Roger Salengro /ID# 223170

location_facility: Omsk Regional Clinic Hospital /ID# 232029

location_facility: Hospital Universitario Reina Sofia /ID# 231843

location_facility: Tel Aviv Sourasky Medical Center /ID# 222117

location_facility: Yaroslavl State Medicat University /ID# 224851

location_facility: Hospital Universitario Ramon y Cajal /ID# 241901

location_facility: Inselspital, Universitätsspital Bern /ID# 224951

location_facility: Republican hospital named after V.A. Baranov /ID# 227661

location_facility: CH Emile Roux Le Puy en Velay /ID# 223688

location_facility: Tri-Service General Hospital /ID# 241746

location_facility: Praxis internistische Rheumatologie /ID# 239226


summary: A multicenter study to evaluate the efficacy and safety of maintenance and long-term treatment administration of upadacitinib, an orally administered Janus kinase 1 inhibitor, in adult participants with Crohn's Disease.

location_facility: Hadassah Medical Center-Hebrew University /ID# 169926

location_facility: KL Ling Gastroenterology and Liver Clinic /ID# 205739

location_facility: Klinicki bolnicki centar Zagreb /ID# 171168

location_facility: CHU Toulouse - Hopital Rangueil /ID# 169784

location_facility: University Hospitals Birmingham NHS Foundation Trust /ID# 169058

location_facility: Lviv Railway Clinical Hospital of branch Healthcare Centers of Public Joint Stoc /ID# 167917

location_facility: Toronto Digestive Disease Asso /ID# 166988

location_facility: University Clinical Centre of the Republic of Srpska /ID# 200743

location_facility: CHRU Tours - Hopital Trousseau /ID# 169783

location_facility: Lahey Hospital and Medical Center /ID# 214724

location_facility: Allegiance Research Specialists /ID# 165298

location_facility: Centex Studies, Inc. - Houston /ID# 201212

location_facility: Duplicate_Tianjin Med Univ General Hosp /ID# 206979

location_facility: Centre Hospitalier de l'Universite de Montreal - CRCHUM /ID# 170122

location_facility: Universitaetsmedizin Essen St. Josef Krankenhaus Werden /ID# 203569

location_facility: Aichi Medical University Hospital /ID# 165989

location_facility: Sir Run Run Shaw Hospital,Meical School Zhejiang University /ID# 204050

location_facility: Polyclinic and Daily Hospital Dr. Al-Tawil /ID# 217843

location_facility: Carl R. Meisner Medical Clinic /ID# 171057

location_facility: CHU Grenoble - Hopital Michallon /ID# 222403

location_facility: Chung-Ang University Hostipal /ID# 207021

location_facility: Clinical Hosp Center Zvezdara /ID# 168216

location_facility: Options Health Research, LLC /ID# 164704

location_facility: A.O. Ospedali Riuniti Villa Sofia - Cervello /ID# 168157

location_facility: City Clinical Hospital No. 31 /ID# 208871

location_facility: Clinica de Investigacion en Reumatologia y Obesidad S.C. /ID# 206843

location_facility: Hospital Universitari Son Espases /ID# 201969

location_facility: The First Hospital of Jilin University /ID# 206865

location_facility: Hospital of Lithuanian University of Health Sciences Kaunas Clinics /ID# 207030

location_facility: Hospital Universitario de Salamanca /ID# 206359

location_facility: CRU Hungary Egeszsegugyi és Szolgaltato Kft. /ID# 205549

location_facility: Policlinico San Martino/Univer /ID# 168162

location_facility: Erciyes University Medical Fac /ID# 171325

location_facility: University Clinical Center Kragujevac /ID# 205856

location_facility: Digestive Health Associates (DHA) - Farmington Hills /ID# 206101

location_facility: Hometown Urgent Care and Resea /ID# 201289

location_facility: Southern California Res. Ctr. /ID# 169653

location_facility: Crystal Pharmacology Research /ID# 166118

location_facility: Digestive Disease Specialists /ID# 201063

location_facility: Pest Megyei Flor Ferenc Korhaz /ID# 206153

location_facility: AGA Clinical Research Associates, LLC /ID# 164641

location_facility: Istanbul University Istanbul Medical Faculty /ID# 171365

location_facility: Hiroshima University Hospital /ID# 165998

location_facility: CHU Amiens-Picardie Site Sud /ID# 171023

location_facility: GIRI Gastrointestinal Research Institute /ID# 166994

location_facility: Cleveland Clinic Main Campus /ID# 209230

location_facility: Chu de Nice-Hopital L'Archet Ii /Id# 171004

location_facility: Iwate Medical University Uchimaru Medical Center /ID# 202465

location_facility: Hospital Garcia de Orta, EPE /ID# 170209

location_facility: Peak Gastroenterology Associates, PC /ID# 170166

location_facility: Hospital das Clinicas da Faculdade de Medicina de Ribeirao Preto - USP /ID# 166859

location_facility: University of Alberta - Zeidler Ledcor Centre /ID# 166987

location_facility: Kaiser Clinica e Hospital Dia /ID# 166858

location_facility: Tokai University Hachioji Hospital /ID# 165984

location_facility: Hepato-Gastroenterologie HK, s.r.o. /ID# 171564

location_facility: Johns Hopkins University School of Medicine /ID# 211939

location_facility: Hospital Clinico Universitario de Valencia /ID# 209658

location_facility: Cabinet Particular Policlinic Algomed /ID# 167832

location_facility: South Eastern Health and Social Care Trust /ID# 205324

location_facility: Hospital Clinico Universidad De Los Andes /ID# 207463

location_facility: Yonsei University Health System Severance Hospital /ID# 167567

location_facility: Tzaneio general hospital of Piraeus /ID# 206435

location_facility: Warrington and Halton Hospitals NHS Foundation Trust /ID# 171396

location_facility: Zentrum für Gastroenterologie Saar MVZ GmbH /ID# 206739

location_facility: The Royal Wolverhampton NHS Trust /ID# 171395

location_facility: The Sixth Affiliated Hosp Sun /ID# 204054

location_facility: CHRU Lille - Hopital Claude Huriez /ID# 206653

location_facility: Digestive Disease Center Gastro /ID# 169518

location_facility: Azienda Ospedaliera San Camillo Forlanini /ID# 168152

location_facility: Taunton and Somerset NHS Foundation Trust /ID# 209666

location_facility: University General Hospital of Heraklion PA.G.N.I /ID# 167031

location_facility: The First Affiliated Hospital of Nanchang University /ID# 204052

location_facility: Clin Res Inst of Michigan, LLC /ID# 170163

location_facility: United Health Services Hospitals, Inc /ID# 217483

location_facility: Niigata University Medical & Dental Hospital /ID# 170042

location_facility: Pusan National University Hospital /ID# 167565

location_facility: Kharkiv City Clinical Hospital No.2 n.a. Prof. O.O. Shalimov /ID# 167918

location_facility: Professor Pasechnikov Gastroenterology and Pankreatology clinic /ID# 202996

location_facility: Hospital da Senhora da Oliveira Guimaraes, EPE /ID# 170204

location_facility: St.Helens and Knowsley Teaching Hospitals NHS Trust /ID# 209087

location_facility: General Hospital of Chest Diseases of Athens SOTIRIA /ID# 202102

location_facility: Centro Hospitalar Universitario de Sao Joao, EPE /ID# 170211

location_facility: Hospital Universitario A Coruna - CHUAC /ID# 203909

location_facility: Columbia Univ Medical Center /ID# 164692

location_facility: Tyler Research Institute, LLC /ID# 168679

location_facility: Mustafa Kemal University Medic /ID# 171328

location_facility: Toyama Prefectural Central Hospital /ID# 217836

location_facility: Fakultna nemocnica s poliklinikou F.D. Roosevelta Banska Bystrica /ID# 169960

location_facility: Hospital Guillermo Grant Benavente de Concepción /ID# 212421

location_facility: P.A. Bayandin Murmansk Regiona /ID# 169590

location_facility: Nemocnice Ceske Budejovice a.s. /ID# 224390

location_facility: Tokyo Medical And Dental University Hospital /ID# 165982

location_facility: Gastroenterology Associates, P.A. of Greenville /ID# 164643

location_facility: School of Medicine University of Puerto Rico-Medical Science Campus /ID# 166769

location_facility: Kazan State Medical University /ID# 169589

location_facility: Zhongshan Hospital Xiamen University /ID# 204986

location_facility: Agaplesion Markus Krankenhaus /ID# 168753

location_facility: Medizinisches Versorgungszentrum Portal 10 /ID# 200212

location_facility: Unidade Local de Saúde do Alto Minho, EPE - Hospital Conde de Bertiandos /ID# 200608

location_facility: Asahikawa Medical University Hospital /ID# 167148

location_facility: Hospital Universitario Virgen Macarena /ID# 202722

location_facility: The First Affiliated Hospital, Sun Yat-sen University /ID# 205227

location_facility: Tongji Hospital Tongji Medical College of HUST /ID# 204051

location_facility: Radboud Universitair Medisch Centrum /ID# 166931

location_facility: Instituto de Investigaciones Aplicadas a la Neurociencias A.C. /ID# 207681

location_facility: Duplicate_Hopital Saint Eloi /ID# 170039

location_facility: Plains Clinical Research Center, LLC /ID# 170169

location_facility: Arizona Arthritis & Rheumatology Research, PLLC /ID# 164702

location_facility: Hospital Universitario y Politecnico La Fe /ID# 202720

location_facility: The Newcastle Upon Tyne Hospitals NHS Foundation Trust /ID# 169063

location_facility: Velocity Clinical Research - Salt Lake City /ID# 166113

location_facility: Stockport NHS foundation trust /ID# 208717

location_facility: CHU de SAINT ETIENNE - Hopital Nord /ID# 171027

location_facility: Gastro Health & Nutrition - Victoria /ID# 167810

location_facility: Clinical Research Center, Faculty of Medicine, Alexandria university. /ID# 209561

location_facility: Debreceni Egyetem Kenezy Gyula Egyetemi Korhaz /ID# 200887

location_facility: Linkou Chang Gung Memorial Hospital /ID# 169804

location_facility: Toho University Sakura Medical Center /ID# 165978

location_facility: University of Chicago Medicine /ID# 165509

location_facility: Perm Clinical Center of the Federal Medical and Biological Agency /ID# 202989

location_facility: CHU UCL Namur - site Godinne /ID# 200295

location_facility: QEII - Health Sciences Centre /ID# 169308

location_facility: Tokyo Women's Medical University Hospital /ID# 205979

location_facility: Atrium Health Carolinas Medical Center /ID# 164632

location_facility: Ottawa Hospital Research Institute /ID# 212412

location_facility: Wake Radiology UNC REX Healthcare - Raleigh Office /ID# 164752

location_facility: Yokkaichi Hazu Medical Center /ID# 167201

location_facility: Duplicate_Care Access Research /ID# 164685

location_facility: Toyohashi Municipal Hospital /ID# 200176

location_facility: Klinicki bolnicki centar Sestre milosrdnice /ID# 171194

location_facility: Hospital Nossa Senhora das Graças /ID# 166856

location_facility: Sisli Etfal Train & Res Hosp /ID# 171327

location_facility: A.O. Per L'Emergenza Cannizzaro /ID# 168161

location_facility: Rapid City Medical Center - GI Research /ID# 201733

location_facility: ASST Fatebenefratelli Sacco - Ospedale Fatebenefratelli e Oftalmico /ID# 168149

location_facility: Azienda Ospedaliero Universitaria Pisana-Stabilimento di Cisanello /ID# 202419

location_facility: Universiti Kebangsaan Malaysia (UKM) Medical Centre /ID# 170780

location_facility: Clinical Research Trials of Florida, Inc. /ID# 203486

location_facility: Clinical Associates in Research Therapeutics of America, LLC /ID# 164675

location_facility: West Tallinn Central Hospital /ID# 202787

location_facility: Shiga University of Medical Science Hospital /ID# 167157

location_facility: University Clinical Center Serbia /ID# 168217

location_facility: Indianapolis Gastroenterology /ID# 164649

location_facility: General Hospital of Thessaloniki Hippokrateio /ID# 208823

location_facility: National Hospital Organization Hirosaki General Medical Center /ID# 165976

location_facility: Hospital Privado Univesitario /ID# 169229

location_facility: Gastroenterology Consultants PC - Roswell /ID# 218218

location_facility: Treasure Valley Medical Research /ID# 215030

location_facility: General Hospital of Athens Evaggelismos and Ophthalmiatrio of Athens Polyclinic /ID# 167033

location_facility: Yamagata University Hospital /ID# 200158

location_facility: Southern Star Research Institute, LLC /ID# 169756

location_facility: Hanyang University Gurihospital /ID# 167563

location_facility: Wakayama Medical University Hospital /ID# 169480

location_facility: Vilnius University Hospital Santaros Klinikos /ID# 203269

location_facility: CNE Vinnytsya Regional Clinical Hospital named after N.I.Pirogov /ID# 222111

location_facility: Soroka University Medical Center /ID# 169911

location_facility: United Medical Doctors - Murrieta /ID# 164602

location_facility: Caprock Gastro Research, LLC /ID# 215436

location_facility: Kyungpook National University Hospital /ID# 207020

location_facility: Froedtert Memorial Lutheran Hospital /ID# 202285

location_facility: Wake Forest Baptist Medical Center /ID# 164755

location_facility: Hospital San Vicente de Paul /ID# 200020

location_facility: Hoag Memorial Hosp Presbyterian /ID# 222538

location_facility: Fondazione Policlinico Universitario Campus Bio-Medico di Roma /ID# 168151

location_facility: Medical Centre of "Ukrainian German Antiulcer Gastroenterology Centre BYK-KYIV" /ID# 203739

location_facility: Sahlgrenska University Hospital /ID# 169170

location_facility: Texas Digestive Disease Consultants /ID# 209954

location_facility: Universitaetsklinikum Erlangen /ID# 203550

location_facility: Gastroenterology Associates of Central Georgia, LLC /ID# 165492

location_facility: Fondazione PTV Policlinico Tor Vergata /ID# 168156

location_facility: Ruijin Hospital, Shanghai Jiaotong University School of Medicine /ID# 204055

location_facility: Advanced Research - Coral Springs /ID# 218019

location_facility: Tel Aviv Sourasky Medical Center /ID# 206450

location_facility: National Taiwan University Hospital /ID# 169805

location_facility: Japanese Red Cross Wakayama Medical Center /ID# 200641

location_facility: Hospital Universitario Vall d'Hebron /ID# 202721

location_facility: Hamamatsu University Hospital /ID# 224402

location_facility: Sahlgrenska University Hospital /ID# 169032

location_facility: Malopolskie Centrum Kliniczne /ID# 202169

location_facility: CHRU Nancy - Hopitaux de Brabois /ID# 170970

location_facility: Inselspital, Universitätsspital Bern /ID# 170994

location_facility: Obudai Egeszsegugyi Centrum Kft. /ID# 201886

location_facility: Universitaetsklinikum Frankfurt /ID# 203567

location_facility: Clinical Research of West Florida, Inc /ID# 208119

location_facility: CB Flock Research Corporation /ID# 166239

location_facility: St George's University Hospitals NHS Foundation Trust /ID# 205550

location_facility: Clinical Research of West Florida, Inc /ID# 205828

location_facility: Hokkaido P.W.F.A.C. Sapporo-Kosei General Hospital /ID# 165975

location_facility: The Dudley Group NHS Foundation Trust /ID# 169057

location_facility: Nara Medical University Hospital /ID# 169213

location_facility: East View Medical Research, LLC /ID# 171132

location_facility: Hyogo Medical University Hospital /ID# 165991

location_facility: Debreceni Egyetem Klinikai Kozpont /ID# 216420

location_facility: Nagoya City University Hospital /ID# 165988

location_facility: Air Force Specialized Hospital /ID# 170993

location_facility: WIP Warsaw IBD Point Profesor Kierkus /ID# 224302

location_facility: Medical Research Center of CT /ID# 164614

location_facility: Houma Digestive Health Special /ID# 164727

location_facility: Faculdade de Medicina do ABC /ID# 166854

location_facility: NYU Langone Long Island Clinical Research Associates /ID# 164627

location_facility: Ctr for Advanced Gastroenterol /ID# 165306

location_facility: The second Affiliated hospital of Zhejiang University school of Medicine /ID# 204058

location_facility: University Clinical Center Tuzla /ID# 210323

location_facility: Private Practice Dr MN Rajabally /ID# 169851

location_facility: Concord Repatriation General Hospital /ID# 171506

location_facility: Royal Victoria Hospital / McGill University Health Centre /ID# 170011

location_facility: Morales Vargas Centro de Investigacion S.C. /ID# 203496

location_facility: Kobenhavns Universitet - Hvidovre Hospital (HH) /ID# 200787

location_facility: Union Hospital Tongji Medical College Huazhong University of Science and Technol /ID# 204065

location_facility: Magyar Honvedseg Egeszsegugyi Kozpont /ID# 200888

location_facility: Universitaetsklinikum Schleswig-Holstein Campus Kiel /ID# 168755

location_facility: Hospital Universitario de Girona Doctor Josep Trueta /ID# 202644

location_facility: Hospital Universitario La Paz /ID# 202725

location_facility: Richmond University Medical Center /ID# 201858

location_facility: Advanced Research Institute, Inc /ID# 164601

location_facility: Gastoenterology Group of Rochester /ID# 166235

location_facility: CHA University Bundang Medical Center /ID# 167569

location_facility: Charite Universitaetsklinikum Berlin - Campus Benjamin Franklin /ID# 169271

location_facility: Kyiv Municipal Clinical Hospital #18 /ID# 207890

location_facility: Dayton Gastroenterology, Inc. /ID# 167623

location_facility: University of Iowa Hospitals and Clinics /ID# 165405

location_facility: Taichung Veterans General Hospital /ID# 169802

location_facility: Healthcare Research Consultant /ID# 166244

location_facility: Clinical Center University of Sarajevo /ID# 201346

location_facility: Universitair Ziekenhuis Leuven /ID# 200031

location_facility: Duplicate_Sjaellands Universitets Hospital /ID# 200786

location_facility: UCSF Center for Colitis and Crohn's Disease /ID# 202372

location_facility: Rush University Medical Center /ID# 165470

location_facility: Landeskrankenhaus Salzburg-Universitätsklinikum der PMU (LKH) /ID# 214468

location_facility: Clin Hosp Ctr Bezanijska Kosa /ID# 168787

location_facility: Hospital Unversitario Marques de Valdecilla /ID# 202495

location_facility: IRCCS Ospedale Sacro Cuore Don Calabria /ID# 168154

location_facility: The Vancouver Clinic, INC. PS /ID# 164874

location_facility: Nanfang Hospital of Southern Medical University /ID# 204056

location_facility: Vanderbilt University Medical Center /ID# 164607

location_facility: Pauls Stradins Clinical University Hospital /ID# 169494

location_facility: Delsol Research Management, Ll /Id# 170164

location_facility: Texas Digestive Disease Consultants /ID# 209803

location_facility: Ohio State University/ Gastroe /ID# 170159

location_facility: Immanuel Kant Baltic Federal University /ID# 203810

location_facility: London Health Sciences Center /ID# 221039

location_facility: Japanese Red Cross Kyoto Daiichi Hosital /ID# 165990

location_facility: Republican hospital named after V.A. Baranov /ID# 206497

location_facility: Citrus Valley Gastroenterology /ID# 166230

location_facility: Clinical Research Center, Faculty of Medicine, Alexandria university. /ID# 171008

location_facility: China Medical University Hospital /ID# 169803

location_facility: East Tennessee Research Institute /ID# 203614

location_facility: Fukuoka University Chikushi Hospital /ID# 214402

location_facility: Gastrointestinal Biosciences Clinical Trials, LLC /ID# 164640

location_facility: Kanazawa University Hospital /ID# 169212

location_facility: Atlanta Gastroenterology Spec /ID# 164698

location_facility: Chikuba Hospital for Proctological and Gastrointestinal Diseases /ID# 165994

location_facility: Azienda Ospedaliero-Universitaria di Modena /ID# 200009

location_facility: Sapporo Medical University Hospital /ID# 167152

location_facility: Universitaetsklinikum Halle (Saale) /ID# 207453

location_facility: National Hospital Organization Takasaki General Medical Center /ID# 167151

location_facility: Hospital Provincial del Centenario /ID# 171251

location_facility: Marmara Universitesi Pendik Egitim ve Arastirma Hastanesi /ID# 171326

location_facility: King's College Hospital NHS Foundation Trust /ID# 169060

location_facility: Hospital Italiano de Buenos Aires /ID# 215542

location_facility: Coral Sea Clinical Research institute /ID# 212989

location_facility: TX Clinical Research Institute /ID# 164719

location_facility: Omega Research Maitland, LLC /ID# 203482

location_facility: Medizinische Universitaet Wien /ID# 169459

location_facility: Yokohama City University Medical Center /ID# 167156

location_facility: MGG Group Co, Inc.Chevy Chase Clinical Research /ID# 164647

location_facility: University of Michigan Comprehensive Cancer Center Michigan Medicine /ID# 164654

location_facility: MNI KRC Kyiv Regional Clinical Hospital /ID# 202456

location_facility: Inonu Universitesi Turgut Ozal /ID# 201266

location_facility: Baylor Scott & White Center for Inflammatory Bowel Diseases /ID# 170161

location_facility: Virginia Mason Medical Center /ID# 164862

location_facility: Allen Whey Khye Lim Professional Corporation /ID# 168047

location_facility: Gazi Universitesi Tip Fakultes /ID# 217445

location_facility: Universitatsklinikum Mannheim /ID# 168754

location_facility: Univ of California San Francis /ID# 164653

location_facility: Baylor College of Medicine - Baylor Medical Center /ID# 164609

location_facility: Faculty of Medicine Ain Shams Research Institute- Clinical Research Centre /ID# 209566

location_facility: Osaka Metropolitan University Hospital /ID# 165999

location_facility: Louisana Research Center, LLC /ID# 164694

location_facility: IRCCS Azienda Ospedaliero-Universitaria di Bologna /ID# 168155

location_facility: Hospital Universitario de Navarra /ID# 202354

location_facility: Gastroenterologie am Mexikoplatz /ID# 203574

location_facility: Inje University Haeundae Hospital /ID# 202631

location_facility: The Jikei University Hospital /ID# 167154

location_facility: London North West University Healthcare NHS Trust /ID# 169056

location_facility: Southern Therapy and Advanced Research (STAR) LLC /ID# 165295

location_facility: Quality Clinical Research Inc. /ID# 170162

location_facility: Instituto Goiano de Gastroenterologia e Endoscopia Digestiva /ID# 166853

location_facility: National Hepatology and Tropical Medicine Research Institute /ID# 170991

location_facility: CHU Bordeaux - Hopital Haut Leveque /ID# 207812

location_facility: General Hospital of Athens Ippokratio /ID# 167032

location_facility: Mentahaz Maganorvosi Kozpont /ID# 201888

location_facility: Great Lakes Gastroenterology Research, LLC /ID# 202006

location_facility: Fondazione Policlinico Universitario Agostino Gemelli IRCCS-Università Cattolica /ID# 168150

location_facility: Hospital Universitario Dr. Negrin /ID# 202723

location_facility: Karolinska University Hospital Solna /ID# 224489

location_facility: Ishida Clinic of IBD and Gastroenterology /ID# 167149

location_facility: Lenasia Clinical Trial Centre /ID# 205143

location_facility: Assaf Harofeh Medical Center /ID# 206449

location_facility: Scott Shulman Medicine Professional Corporation /ID# 169065

location_facility: The Second Xiangya Hospital of Central South University /ID# 204057

location_facility: Clinical Research Center, Faculty of Medicine, Alexandria university. /ID# 171017

location_facility: Hospital de Clinicas de Porto Alegre /ID# 166855

location_facility: Hospital Clinic de Barcelona /ID# 202726

location_facility: Encore Borland-Groover Clinical Research /Id# 203500

location_facility: HonorHealth Research Institute - Shea /ID# 164725

location_facility: Montefiore Medical Center - Moses Campus /ID# 166242

location_facility: ASST Grande Ospedale Metropolitano Niguarda /ID# 170906

location_facility: MediSphere Medical Research Center /ID# 166233

location_facility: Osaka Medical and Pharmaceutical University Hospital /ID# 206323

title: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Maintenance and Long-Term Extension Study of the Efficacy and Safety of Upadacitinib (ABT-494) in Subjects With Crohn's Disease Who Completed the Studies M14-431 or M14-433

location_country:
Germany
Ireland
Poland
Argentina
Australia
Brazil
Japan
Bosnia and Herzegovina
Turkey
Croatia
Chile
Czechia
Canada
Serbia
France
Slovenia
Lithuania
Colombia
Portugal
Slovakia
Hungary
Hong Kong
Denmark
Switzerland
United States
Latvia
Ukraine
Romania
Belgium
China
Malaysia
Estonia
Puerto Rico
Egypt
Italy
United Kingdom
Singapore
Sweden
Netherlands
Austria
Mexico
Korea, Republic of
Spain
Greece
South Africa
Taiwan
Bulgaria
Russian Federation
Israel